The effect of regular physical activity on women's self-confidence levels: An exploratory research

Introduction: It is known that physical activity is good for many diseases such as obesity, heart diseases, various types of cancer, musculoskeletal disorders. Compared to men, women's participation in physical activity is more limited. Physical activity, on the other hand, contributes to both the increase in the quality of life and the socialization of people. In this context, the aim of this study is to determine the self-confidence levels of women who regularly participate in physical activity. Method: In the research, besides the personal information form prepared by the researchers, the self-confidence scale was used. The sample population survey in Turkey Kocaeli province has created 408 women participating regularly in physical activity. In the analysis of the data, arithmetic means, frequency and percentage values were taken. As a result of the normality test, it was seen that it showed a normal distribution. Accordingly, independent sample t-test was used in the analysis of paired groups and one way Anova tests were used in the analysis of multiple groups. Results: As a result of the analysis, no significant difference was found in any sub-dimension according to the marital status variable. Significant differences were observed in the sub-dimensions of the scale according to the variables of income level, physical activity duration, education level and age. Conclusion: It has been observed that as the duration of physical activity increases, the level of self-confidence increases. In addition, it was concluded that age and educational status were directly related to self-confidence, and as education level and age increased, self-confidence increased

In situ identification of Gram-negative bacteria in human lungs using a topical fluorescent peptide targeting lipid A

Acknowledgment to AAAS for publishing this manuscript with DOI 10.1126/scitranslmed.aal0033 https://www.science.org/doi/10.1126/scitranslmed.aal0033Respiratory infections in mechanically ventilated patients caused by Gram-negative bacteria are a major cause of morbidity. Rapid and unequivocal determination of the presence, localization, and abundance of bacteria is criti cal for positive resolution of the infections and could be used for patient stratification and for monitoring treat ment efficacy. Here, we developed an in situ approach to visualize Gram-negative bacterial species and cellular infiltrates in distal human lungs in real time. We used optical endomicroscopy to visualize a water-soluble optical imaging probe based on the antimicrobial peptide polymyxin conjugated to an environmentally sensitive fluoro phore. The probe was chemically stable and nontoxic and, after in-human intrapulmonary microdosing, enabled the specific detection of Gram-negative bacteria in distal human airways and alveoli within minutes. The results suggest that pulmonary molecular imaging using a topically administered fluorescent probe targeting bacterial lipid A is safe and practical, enabling rapid in situ identification of Gram-negative bacteria in humans.This work was supported by Wellcome Trust, the Department of Health Healthcare Innovation Challenge Fund (HICF-0510-069), and the Engineering and Physical Sciences Research Council Interdisciplinary Research Collaboration “Proteus” (EP/K03197X/1). The GMP activities were supported by the National Institute for Health Research (NIHR) BRC GMP Unit at Guy’s and St. Thomas’ NHS Foundation Trust and NIHR Biomedical Research Centre based at Guy’s and St. Thomas’ NHS Foundation Trust and King’s College London

Association between intra-radicular posts and periapical lesions in endodontically treated teeth

Introduction: A significant number of endodontically treated teeth restored with posts have associated periapical lesions, and several authors have discussed the probable causes of the development of these. Attention has been focused on restorative procedures performed after endodontic treatment and their association with the prognosis of endodontic therapy because a number of root-filled teeth will require post- and core-retained restorations. Purpose: The purpose of this study was to evaluate, by examination of periapical radiographs, whether the placement of intra-radicular posts in endodontically treated teeth may act as a risk factor for development of periapical lesions. Material and Methods: This case-control study analyzed periapical radiographs of 72 endodontically treated teeth with coronal restorations. All radiographs were obtained from a single private practice. Specimens were assigned to 2 groups: Group 1 (control) was composed of teeth without periapical lesions and Group 2 (case) was composed of teeth with periapical lesions. The number of teeth with and without posts in each group was recorded. Three calibrated examiners analyzed the radiographs visually under X4 magnification. Results: In Group 1, 28 (65.1%) out of 43 teeth were restored with posts. In Group 2, 24 (82.8%) out of 29 teeth had intra-radicular posts. The interpretation of chi-square test showed that these percentages were not significantly different (x²=2.687; p=0.101). Odds ratio was 2.571 (0.815-8.118), which indicates that there was no statistically significant association between periapical lesions and posts. Conclusion: Intra-radicular posts placed in endodontically treated teeth were not a significant risk factor for development of periapical lesions in the practice where the cohort of patients was treated

Cross-sectional evaluation of the periapical status as related to quality of root canal fillings and coronal restorations in a rural adult male population of Turkey

<p>Abstract</p> <p>Background</p> <p>To determine the prevalence of periapical lesions in root canal-treated teeth in a rural, male adult, Turkish population and to investigate the influence of the quality of root canal fillings on prevalence of periapical lesions.</p> <p>Methods</p> <p>The sample for this cross-sectional study consisted of 552 adult male patients, 18-32 years of age, presenting consecutively as new patients seeking routine dental care at the Dental Sciences of Gulhane Military Medicine, Ankara. The radiographs of the 1014 root canal-treated teeth were evaluated. The teeth were grouped according to the radiographic quality of the root canal filling and the coronal restoration. The criteria used for the examination were slightly modified from those described by De Moor. Periapical status was assessed by the Periapical Index scores (PAI) proposed by Orstavik.</p> <p>Results</p> <p>The overall success rate of root canal treatment was 32.1%. The success rates of adequately root canal treatment were significantly higher than inadequately root canal treatment, regardless of the quality or presence of the coronal restoration (P < .001). In addition, the success rate of inadequate root canal treatment was also significantly affected by the quality of coronal restorations.</p> <p>Conclusions</p> <p>Our results revealed a high prevalence of periapical lesions in root canal treatment, which is comparable to that reported in other methodologically compatible studies from diverse geographical locations. In addition, the results from the present study confirm the findings of other studies that found the quality of the root canal treatment to be a key factor for prognosis with or without adequate coronal restoration.</p