Histological changes in the heart and the proximal aorta in experimental diabetic rats fed with Piper sarmentsoum

Cardiovascular complications are one of the major causes of death in diabetes mellitus. Piper sarmentosum (P.s) is an herb that possesses antihyperglycaemic effects. The main aim of the study was to observe the histological changes in the heart and the proximal aorta of streptozotocin-induced diabetic rats following P.s administration. Twenty-four male Sprague-Dawley rats (n=24) were equally randomized into four groups: control group supplemented with normal saline (C); control group supplemented with P.s (CTx) ; diabetic group supplemented with normal saline (D) and, diabetic group supplemented with P.s (DTx). Diabetes was induced by STZ (50mg/kg body weight) intramuscularly. P.s extract (0.125g/kg) was administered orally for 28 days, following four weeks of STZ induction. The cardiac and aortic tissues were collected and processed under different stains: Haematoxylin and Eosin (H & E), Verhoeff-Van Gieson (VVG), Masson’s Trichome (MT) and Periodic Acid- Schiff (PAS). There were abnormal cardiomyocytes nuclei, disarray of myofibres and increase in connective tissue deposits in cardiac tissues of the diabetic untreated group. The thickness of tunica media and ratio of tunica intima to media were found to be significantly increased in the aorta of diabetic untreated group (P < 0.05) compared to the control group. There weredegenerative changes in the proximal aorta in diabetic untreated groups. All the histological damages of cardiac and aortic tissues were found to be lesser in the diabetic treated groups. Supplementation with P.s extract prevented the oxidative damage arising from diabetes mellitus, and reduced its complications

The cientificWorldJOURNAL Research Article Immunostimulant Effect of Egyptian Propolis in Rabbits

The present experiment was conducted to study the effect of ethanolic extract of Egyptian propolis given alone or in combination with inactivated Pasteurella multocida vaccine on rabbits challenged with a virulent strain of Pasteurella multocida. Fifty-six NewZealand rabbits, 6-8 weeks old and non-vaccinated against pasteurellosis, were randomly divided into eight equal groups. The first group was kept as a control for the experiment. The other groups received different treatments with propolis extract, inactivated vaccine, or both. The experiment continued for seven weeks during which clinical signs, body weight, and mortality rate were monitored, and blood samples were collected weekly for evaluating the leukogram, serum biochemistry, and immune response in all groups of animals. At the end of the seventh week, the animals were subjected to challenge with a virulent strain of Pasteurella multocida. Two weeks later, tissue specimens were collected from different organs for histopathological examination. Results showed that rabbits of the groups treated with both propolis and the vaccine by different routes appeared healthy after challenge. It has been concluded that alcoholic extract of propolis administrated in combination with inactivated Pasteurella multocida vaccine has no adverse effects on the general health conditions and enhances immune response in rabbits

ANTIVIRAL AND IMMUNE STIMULANT ACTIVITIES OF GLYCYRRHIZIN AGAINST DUCK HEPATITIS VIRUS

This study was conducted to investigate the effect of glycyrrhizin as an immune stimulant against duck hepatitis virus (DHV). In vitro study was carried out to determine cytotoxic and antiviral effects of glycyrrhizin in VERO cells. In vivo study was performed on 40 one-day-old White Pekin ducklings. –and the birds weres divided into 4 groups: control, glycyrrhizin treated, vaccinated with live attenuated DHV vaccine and glycyrrhizin treated and vaccinated; to investigate the changes in immunity and challenge test. Blood samples were collected from each duckling for evaluation of cellular and humeral immunity. The in vitro results revealed that glycyrrhizin had antiviral and no toxic effects till 106 dilutions. Higher antibody titer was observed from the 5th week till the end of experiment in glycyrrhizin and vaccinated group. Treatment with glycyrrhizin alone or with DHV vaccine demonstrated a pronounced lymphocytic proliferation response after 4 days post-inoculation till the end of experiment, while vaccinated group revealed a pronounced proliferation response after 24 days post-inoculation. Treatment with glycyrrhizin alone or combination with DHV vaccine revealed good immune stimulant and antiviral effect against DHV

Performance analysis of wireless transmission of compressed images using DCT‐OFDMA system with different compression schemes

Abstract Transmitting images over an Orthogonal Frequency Division Multiplexing Access (OFDMA) system poses a significant challenge. The process entails sending a substantial amount of data, which consumes a significant amount of bandwidth. Consequently, compressing the transmitted image becomes essential to reduce the required bandwidth. The aim of this paper is to examine and analyse the wireless transmission of a compressed image via Discrete Cosine Transform (DCT‐OFDMA). A comparison is made with Discrete Fourier Transform (DFT‐OFDMA), across various subcarrier mapping schemes (localized and inter‐leaved), and different modulation schemes (16 Quadrature Amplitude Modulation (16QAM) and Quadrature Phase Shift Keying (QPSK)) using vehicular A, Stanford University Interim (SUI3), and uniform channel models. To evaluate the performance of the system, the minimum Signal‐to‐Noise Ratio (SNR) necessary to recover the transmitted compressed image is calculated. This work considers nine standard compression techniques. The results are carried out using the MATLAB simulator. According to the simulation results, the minimum SNR required to recover the transmitted compressed image was found to be 19 dB. This result was achieved when using Discrete Cosine Transform‐Loaclized‐Orthogonal Frequency Division Multiplexing Access (DCT‐LOFDMA) with QPSK modulation and set partitioning in hierarchical trees (SPIHT) compression method over the SUI3 channel model. Moreover, it was observed that the DCT‐LOFDMA and DFT‐IOFDMA systems attained equal SNR while utilizing the SPIHT_3D compression technique and QPSK modulation on the SUI3 channel model. Overall, the results suggest that the performance of DCT‐based localized OFDMA is somewhat superior to DFT‐based localized OFDMA, particularly when utilizing the SUI3 channel model and the QPSK modulation scheme. Therefore, it is feasible to transmit and receive a compressed image effectively over an OFDMA system with DCT

Performance analysis of wireless compressed-image transmission over DST-based OFDMA systems

Abstract Multimedia data, like images, consumes significant bandwidth when transmitted over wireless systems. Therefore, compressing transmitted images becomes crucial to reduce the required bandwidth and improve energy efficiency. This work aims to analyze the performance of transmitting wireless compressed images over a recent Discrete Sine Transform (DST)-Based Orthogonal Frequency Division Multiple Access (DST-OFDMA) system. It investigates the effectiveness of several image compression methods by determining the minimum Signal-to-Noise Ratio (SNR) required for each method to achieve error-free image recovery at the receiver. This work considers different modulation schemes including 16QAM and QPSK, as well as different subcarrier mapping schemes (localized and interleaved) over vehicular A, SUI3, and uniform channels. Nine standard compression methods are used for analyzing the performance of the DST-OFDMA system and compared it with that of the conventional Discrete Fourier Transform (DFT)-based OFDMA (DFT-OFDMA) system. The results show that the performance of DST-OFDMA outperforms that of DFT-OFDMA, especially when QPSK modulation is used. Simulation results demonstrate that the interleaved DST-OFDMA (DST-IOFDMA) system, employing the SPIHT_3D compression method and QPSK modulation (over the SUI3 channel model), achieves the lowest SNR value required for compressed image recovery, approximately 18 dB. This indicates that the SPIHT_3D compression method exhibits lower power consumption compared to other methods as well as high bandwidth efficiency

Immunostimulant Effect of Egyptian Propolis in Rabbits

The present experiment was conducted to study the effect of ethanolic extract of Egyptian propolis given alone or in combination with inactivated Pasteurella multocida vaccine on rabbits challenged with a virulent strain of Pasteurella multocida. Fifty-six New-Zealand rabbits, 6–8 weeks old and non-vaccinated against pasteurellosis, were randomly divided into eight equal groups. The first group was kept as a control for the experiment. The other groups received different treatments with propolis extract, inactivated vaccine, or both. The experiment continued for seven weeks during which clinical signs, body weight, and mortality rate were monitored, and blood samples were collected weekly for evaluating the leukogram, serum biochemistry, and immune response in all groups of animals. At the end of the seventh week, the animals were subjected to challenge with a virulent strain of Pasteurella multocida. Two weeks later, tissue specimens were collected from different organs for histopathological examination. Results showed that rabbits of the groups treated with both propolis and the vaccine by different routes appeared healthy after challenge. It has been concluded that alcoholic extract of propolis administrated in combination with inactivated Pasteurella multocida vaccine has no adverse effects on the general health conditions and enhances immune response in rabbits