9 research outputs found
Clinical significance of proliferative potential of occult metastatic cells in bone marrow of patients with breast cancer
Illegitimate villin transcripts in normal bone marrow precludes detection of colon cancer micrometastases.
Villin is a specific marker for normal and tumoral colon tissue. We have developed a highly sensitive assay using reverse transcription (RT) and real-time PCR to detect villin transcripts. The sensitivity of detection is one colon cancer cell. However, high levels of illegitimate villin transcripts were observed in normal bone marrow, precluding the use of villin RT-PCR for routine detection of colon cancer cells in bone marrow of patients with colon cancer
Amélioration du contrôle de qualité pour les dosages de récepteurs stéroïdiens: analyse des distributions dans plus de 40 000 cancers primitifs du sein
The resistance of B-CLL cells to DNA damage-induced apoptosis defined by DNA microarrays
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