Bulk and contact-sensitized photocarrier generation in single layer TPD devices

In this paper, we report on the photoelectronic properties of TPD studied in sandwich geometry. In particular, we have obtained from both forward and reverse bias measurements the "mew-tau" product for holes in TPD. "mew" is the hole mobility and "tau" the carrier trapping time. The "mew-tau" product is a measure of the electronic quality of the material and allows a quantitative comparison of different samples. We have carried out numerical simulations to understand the photocurrent in these structures. We show that in reverse bias, the photocurrent (PC) is due to bulk. The carrier generation is governed by field assisted exciton dissociation at electric fields greater than 10^6 V/cm. At lower fields the generation of carriers occurs spontaneously in the bulk of the sample. In forward bias, the photocurrent is due to exciton dissociation at the ITO contact. We also obtain a "mew-tau" product for holes from forward bias PC measurements which is in agreement with the value obtained from reverse bias measurements. Based on our experiments, we demonstrate that TPD in a sandwich structure is a good candidate for cheap large area solar blind UV detector arrays.Comment: Submitted to J. Appl. Phy

The effect of Coulombic friction on spatial displacement statistics

The phenomenon of Coulombic friction enters the stochastic description of dry friction between two solids and the statistic characterization of vibrating granular media. Here we analyze the corresponding Fokker-Planck equation including both velocity and spatial components, exhibiting a formal connection to a quantum mechanical harmonic oscillator in the presence of a delta potential. Numerical solutions for the resulting spatial displacement statistics show a crossover from exponential to Gaussian displacement statistics. We identify a transient intermediate regime that exhibits multiscaling properties arising from the contribution of Coulombic friction. The possible role of these effects during observations in diffusion experiments is shortly discussed.Comment: 11 pages, 9 figure

Acupuncture Point Localization Varies Among Acupuncturists

Background: Studies assessing the point-specific effect of acupuncture or the characteristics of acupuncture points (APs) tend to yield inconclusive results. In order to identify a possible confounding factor, we aimed to examine the variability in AP localization by means of a survey. Material and Methods: Attendees of the 14th ICMART (International Council of Medical Acupuncture and Related Techniques) congress as well as DAGfA (German Medical Society of Acupuncture) lecturers and students were asked to locate and mark the APs LI 10 and TH 5 on a research assistant's arm. Identified points were transferred into a coordinate system, and the respective bivariate distribution function was calculated. Additionally, participants filled out a questionnaire about their acupuncture education and experience, the acupuncture style and point localization techniques used most frequently, and their estimation of the size of an AP. Results: The areas of the ellipses, theoretically containing 95% of AP localizations, varied between 44.49 and 5.18 cm(2). The largest distance between 2 identified points was 8.45 cm for LI 10 and 5.3 cm for TH 5. Apart from being trained at the same school, no other factor could be identified that determined the variability in AP localization. Conclusion: Our results indicate that congruity of AP localization among experienced acupuncturists might be low. Although there are some limitations to our results, this possible bias should be taken into account when conducting acupuncture trials and interpreting results of previous acupuncture studies

Determination of the trap-assisted recombination strength in polymer light emitting diodes

The recombination processes in poly(p-phenylene vinylene) based polymer light-emitting diodes (PLEDs) are investigated. Photogenerated current measurements on PLED device structures reveal that next to the known Langevin recombination also trap-assisted recombination is an important recombination channel in PLEDs, which has not been considered until now. The dependence of the open-circuit voltage on light intensity enables us to determine the strength of this process. Numerical modeling of the current-voltage characteristics incorporating both Langevin and trap-assisted recombination yields a correct and consistent description of the PLED, without the traditional correction of the Langevin prefactor. At low bias voltage the trap-assisted recombination rate is found to be dominant over the free carrier recombination rate.

Ultrastructural visualization of cytoskeletal mRNAs and their associated proteins using double-label in situ hybridization

We have been able to visualize cytoskeletal messenger RNA molecules at high resolution using nonisotopic in situ hybridization followed by whole-mount electron microscopy. Biotinated cDNA probes for actin, tubulin, or vimentin mRNAs were hybridized to Triton-extracted chicken embryo fibroblasts and myoblasts. The cells were then exposed to antibodies against biotin followed by colloidal gold-conjugated antibodies and then critical-point dried. Identification of mRNA was possible using a probe fragmented to small sizes such that hybridization of several probe fragments along the mRNA was detected as a string of colloidal gold particles qualitatively and quantitatively distinguishable from nonspecific background. Extensive analysis showed that when eight gold particles were seen in this iterated array, the signal to noise ratio was greater than 30:1. Furthermore, these gold particles were colinear, often spiral, or circular suggesting detection of a single nucleic acid molecule. Antibodies against actin, vimentin, or tubulin proteins were used after in situ hybridization, allowing simultaneous detection of the protein and its cognate message on the same sample. This revealed that cytoskeletal mRNAs are likely to be extremely close to actin protein (5 nm or less) and unlikely to be within 20 nm of vimentin or tubulin filaments. Actin mRNA was found to be more predominant in lamellipodia of motile cells, confirming previous results. These results indicate that this high resolution in situ hybridization approach is a powerful tool by which to investigate the association of mRNA with the cytoskeleton

A simple measure of memory for dynamical processes described by the generalized Langevin equation

Memory effects are a key feature in the description of the dynamical systems governed by the generalized Langevin equation, which presents an exact reformulation of the equation of motion. A simple measure for the estimation of memory effects is introduced within the framework of this description. Numerical calculations of the suggested measure and the analysis of memory effects are also applied for various model physical systems as well as for the phenomena of ``long time tails'' and anomalous diffusion

Examining the mechanical influences upon the sciatic nerve at the sciatic nerve-hamstring muscle interface during active and passive knee extension

Background: Ultrasound imaging has been used to examine movement of the peripheral nervous system in response to normal body movements and therapeutic exercises, such as neural mobilisation. Researchers have clearly established that peripheral nerves must be able to move in relation to their surrounding interfacing tissues. However, to date the mechanical influences that these interfacing tissues have upon nerve movement has yet to be determined. Purpose: We sought to examine the different mechanical influences that the surrounding hamstring muscles have upon the sciatic nerve during lower limb movements. A better understanding of the mechanical influences imposed upon the sciatic nerve, from surrounding tissues, would be beneficial to then examine these relationships in clinical populations including lumbar-related leg pain. Methods: A cross-sectional, observational laboratory study was conducted in ten healthy participants (2 males, 8 females; age 24 ± 5 years (mean ± SD); height 169 ± 7 cm; weight, 65 ± 9 kg; body mass index, 23 ± 3 kg/m2) who underwent knee extension movements (active and passive) in upright sitting and side-lying positions. High-resolution ultrasound imaging was used to assess lateral displacement of the sciatic nerve and hamstring muscles (superficial and deep regions). Ultrasound elastography was used to calculate the shear strain between the sciatic nerve-hamstring muscle interface. Electromyography was used to assess the electrical activity of the hamstring muscles during the active and passive limb movements. Range of motion of the pelvis, hip and knee joints was measured with inertial sensors in order to standardize the limb movements among participants. Results: In both the sitting and side-lying positions, passive knee extension resulted in greater differential lateral displacement of the sciatic nerve versus the hamstring muscles along with greater shear strain at the sciatic nerve-hamstring muscle interface when compared to active knee extension. Conclusion: The findings of the study suggest that the greatest amount of differential lateral displacement between the sciatic nerve and the hamstring muscles occurs during passive knee extension compared to active knee extension. Furthermore, this greater differential movement was associated with increased sciatic nerve-hamstring muscle shear strain in the passive compared to the active condition. Implications: Treatment interventions, such as neural mobilisation exercises, employ either active of passive limb movements to induce peripheral nerve movement in disorders where nerve movement is believed to be compromised. Knee extension, whether active or passive, is commonly utilised to induce movement of the sciatic nerve relative to the interfacing hamstring muscles. It would appear from this research that although passive knee extension resulted in greater movement of the sciatic nerve relative to the hamstring muscles, this was accompanied by an increase in nerve-muscle interface shear strain. In many clinical populations where nerve movement is believed to be compromised, it may be clinically prudent to avoid increases in shear strain as this may cause adverse effects from an already mechanosensitised nervous system. Keywords: Sciatic nerve, ultrasound, elastography Funding acknowledgements: Nil

Neutron and proton drip lines using the modified Bethe-Weizsacker mass formula

Proton and neutron separation energies have been calculated using the extended Bethe-Weizsacker mass formula. This modified Bethe-Weizsacker mass formula describes minutely the positions of all the old and the new magic numbers. It accounts for the disappearance of some traditional magic numbers for neutrons and provides extra stability for some new neutron numbers. The neutron and proton drip lines have been predicted using this extended Bethe-Weizsacker mass formula. The implications of the proton drip line on the astrophysical rp-process and of the neutron drip line on the astrophysical r-process have been discussed.Comment: 5 pages, 2 figure