Deliverable 1.3: The economics of technological innovations to mitigate ecosystem effects of fishing: the pulse trawl in the North Sea

In this study we focused on the mitigation of the benthic impacts of the beam trawl fisheries for sole through the use of electricity as a technological innovation (pulse trawls replacing traditional beam trawl) and particularly on the economics of the gear transition. We identify drivers that probably influenced the technological change and got insight in the factors that may promote or hamper the use pulse trawl. The studies show that the pulse trawl is economically more profitable than the traditional beam trawl when targeting sole. This is particularly true when fuel prices are high and also when the landing obligation is implemented (because the catch is more selective). In the Dutch fishery, the wages of the crew operating with pulse are also higher which probably explain the support that the pulse trawl received from the crew. However this is not the case in the Belgian fleet where crew wages are based on value of landings only (as opposed to value of landings minus fuel price in the Dutch fishery). In addition to the good economic performances of the pulse trawl, non-economic factors have played a role in the uptake of the pulse trawl in the sole fishery. In particular, the information sharing amongst fisher through study groups and demonstration days have accelerated the process in the Netherlands. The support of the Dutch government was also influential. In contrast, barriers such as limiting days at sea in the North Sea for Belgian fishers and the controversial image of the pulse in Belgium may have hindered the adoption of pulse in Belgium

PROCESS AND MATERIAL OPTIMISATIONS FOR INTEGRATION OF CHOPPED GLASS FIBRES IN LASER SINTERED POLYMER PARTS

Additively manufactured polymer composites gain popularity in a variety of industries such as aerospace, biomedical and automotive. Laser sintering (LS) is a well-known AM process that typically uses polyamide which can serve as matrix material. Hence LS has the potential to produce reinforced polymers that can meet demanding requirements. In previous research, issues with powder flowability and poor fibre dispersion led to limited increase of mechanical properties. To overcome this, a novel fibre deposition system was recently developed and optimised at KU Leuven to successfully produce fibre reinforced LS samples with random inter- and intralayer fibre orientations. A limited but promising influence of deposited glass fibres on produced LS parts was noted after mechanical testing. In this work, the influence of different (heat) treatments on glass fibres used during LS will be discussed as well as the resulting differences in the fibre/matrix behaviour as analysed through hot stage microscopy.Mechanical Engineerin

A prospective study on rapid exome sequencing as a diagnostic test for multiple congenital anomalies on fetal ultrasound

Objective: Conventional genetic tests (quantitative fluorescent-PCR [QF-PCR] and single nucleotide polymorphism-array) only diagnose ~40% of fetuses showing ultrasound abnormalities. Rapid exome sequencing (rES) may improve this diagnostic yield, but includes challenges such as uncertainties in fetal phenotyping, variant interpretation, incidental unsolicited findings, and rapid turnaround times. In this study, we implemented rES in prenatal care to increase diagnostic yield. Methods: We prospectively studied 55 fetuses. Inclusion criteria were: (a) two or more independent major fetal anomalies, (b) hydrops fetalis or bilateral renal cysts alone, or (c) one major fetal anomaly and a first-degree relative with the same anomaly. In addition to conventional genetic tests, we performed trio rES analysis using a custom virtual gene panel of ~3850 Online Mendelian Inheritance in Man (OMIM) genes. Results: We established a genetic rES-based diagnosis in 8 out of 23 fetuses (35%) without QF-PCR or array abnormalities. Diagnoses included MIRAGE (SAMD9), Zellweger (PEX1), Walker-Warburg (POMGNT1), Noonan (PTNP11), Kabuki (KMT2D), and CHARGE (CHD7) syndrome and two cases of Osteogenesis Imperfecta type 2 (COL1A1). In six cases, rES diagnosis aided perinatal management. The median turnaround time was 14 (range 8-20) days. Conclusion: Implementing rES as a routine test in the prenatal setting is challenging but technically feasible, with a promising diagnostic yield and significant clinical relevance

Challenging the ‘artisanal vs. industrial’ dichotomy in French Atlantic fisheries: An organizational typology of multi-vessel fishing firms

We put under scrutiny the ‘artisanal vs. industrial’ dichotomy used by French fisheries management for classifying fishing operations. Recent evolutions in the Atlantic fishing sector urge us to question its applicability. In particular the definition of the so-called ‘artisanal fishing model’ is under pressure (e.g., decline of family-based fishing, multi-vessel companies increasingly common, emergence of new forms of firm governance). Using mixed-method research (interviews, multiple correspondence analysis (MCA) and hierarchical clustering), we propose a new typology for classifying multi-vessel fishing firms, based on six organizational attributes (ownership structure, firm structure, management strategy, firm size, fishing strategy and valorization strategy). We have carried out a three-step analysis. First, the MCA suggests that the diversity of organizational forms can be described to a great extent in terms of the profile of the owner and the firm’s management and valorization strategies. The cluster analysis then separates organizational configurations in five types, based on cluster-specific modalities: access to key information, legal form, vessel maintenance and standardization, growth objectives and management structure. The final description of the types draws from additional interview data as well as variables that were not used in the analysis. The typology captures the diversity of governance configurations currently existing in the sector, while providing some insight into their origins and future trajectories. We conclude that the artisanal model is outdated and insufficient for describing the organizational diversity of modern-day fishing firms, especially those in the 12–18 m and 18–24 m segments

Systemic biochemical markers of joint metabolism and inflammation in relation to radiographic parameters and pain of the knee : Data from CHECK, a cohort of early-osteoarthritis subjects

Objective: To investigate associations of biochemical markers of joint metabolism and inflammation with minimum joint space width (JSW) and osteophyte area (OP area) of knees showing no or doubtful radiographic osteoarthritis (OA) and to investigate whether these differed between painful and non-painful knees. Design: Serum (s-) and urinary (u-) levels of the cartilage markers uCTX-II, sCOMP, sPIIANP, and sCS846, bone markers uCTX-I, uNTX-I, sPINP, and sOC, synovial markers sPIIINP and sHA, and inflammation markers hsCRP and erythrocyte sedimentation rate (ESR) were assessed in subjects from CHECK (Cohort Hip and Cohort Knee) demonstrating Kellgren and Lawrence grade ≤1 OA on knee radiographs. Minimum JSW and OP area of these knees were quantified in detail using Knee Images Digital Analysis (KIDA). Results: uCTX-II levels showed negative associations with minimum JSW and positive associations with OP area. sCOMP and sHA levels showed positive associations with OP area, but not with minimum JSW. uCTX-I and uNTX-I levels showed negative associations with minimum JSW and OP area. Associations of biochemical marker levels with minimum JSW were similar between painful and non-painful knees, associations of uCTX-II, sCOMP, and sHA with OP area were only observed in painful knees. Conclusions: In these subjects with no or doubtful radiographic knee OA, uCTX-II might not only reflect articular cartilage degradation but also endochondral ossification in osteophytes. Furthermore, sCOMP and sHA relate to osteophytes, maybe because synovitis drives osteophyte development. High bone turnover may aggravate articular cartilage loss. Metabolic activity in osteophytes and synovial tissue, but not in articular cartilage may be related to knee pain