Infinity

Prose by Eric Baugh. Finalist in the 2018 Manuscripts Prose Contest

Research and Use of Nuclear Energy — Its Ambivalence(s) in Historical Context

The discovery of a scientific fact is initially not ambivalent; only in its possibilities of use does its ambivalence become apparent. But the socially evaluated positive uses and negative misuses of scientific knowledge cannot be clearly distinguished, and both can also appear ambivalent in turn. In this sense, consequently, scientists already bear responsibility for their discoveries. Moreover, in the case of experimental research, the question must be asked, to what extent its realization already interferes with what is happening and thus acquires an ambivalent character (which, however, must be distinguished from the ambivalence of its use). With those issues in mind, the article discusses the questions raised by the discovery and early use of nuclear energy

Cubic Augmentation of Planar Graphs

In this paper we study the problem of augmenting a planar graph such that it becomes 3-regular and remains planar. We show that it is NP-hard to decide whether such an augmentation exists. On the other hand, we give an efficient algorithm for the variant of the problem where the input graph has a fixed planar (topological) embedding that has to be preserved by the augmentation. We further generalize this algorithm to test efficiently whether a 3-regular planar augmentation exists that additionally makes the input graph connected or biconnected. If the input graph should become even triconnected, we show that the existence of a 3-regular planar augmentation is again NP-hard to decide.Comment: accepted at ISAAC 201

Combinatorial Properties of Triangle-Free Rectangle Arrangements and the Squarability Problem

We consider arrangements of axis-aligned rectangles in the plane. A geometric arrangement specifies the coordinates of all rectangles, while a combinatorial arrangement specifies only the respective intersection type in which each pair of rectangles intersects. First, we investigate combinatorial contact arrangements, i.e., arrangements of interior-disjoint rectangles, with a triangle-free intersection graph. We show that such rectangle arrangements are in bijection with the 4-orientations of an underlying planar multigraph and prove that there is a corresponding geometric rectangle contact arrangement. Moreover, we prove that every triangle-free planar graph is the contact graph of such an arrangement. Secondly, we introduce the question whether a given rectangle arrangement has a combinatorially equivalent square arrangement. In addition to some necessary conditions and counterexamples, we show that rectangle arrangements pierced by a horizontal line are squarable under certain sufficient conditions.Comment: 15 pages, 13 figures, extended version of a paper to appear at the International Symposium on Graph Drawing and Network Visualization (GD) 201

A novel mechanism of RNase L inhibition: Theiler\u27s virus L* protein prevents 2-5A from binding to RNase L

<div><p>The OAS/RNase L pathway is one of the best-characterized effector pathways of the IFN antiviral response. It inhibits the replication of many viruses and ultimately promotes apoptosis of infected cells, contributing to the control of virus spread. However, viruses have evolved a range of escape strategies that act against different steps in the pathway. Here we unraveled a novel escape strategy involving Theiler’s murine encephalomyelitis virus (TMEV) L* protein. Previously we found that L* was the first viral protein binding directly RNase L. Our current data show that L* binds the ankyrin repeats R1 and R2 of RNase L and inhibits 2’-5’ oligoadenylates (2-5A) binding to RNase L. Thereby, L* prevents dimerization and oligomerization of RNase L in response to 2-5A. Using chimeric mouse hepatitis virus (MHV) expressing TMEV L*, we showed that L* efficiently inhibits RNase L <i>in vivo</i>. Interestingly, those data show that L* can functionally substitute for the MHV-encoded phosphodiesterase ns2, which acts upstream of L* in the OAS/RNase L pathway, by degrading 2-5A.</p></div

Synchrotron x-ray study of lattice vibrations in CdCr2O4

Using inelastic x-ray scattering we have investigated lattice vibrations in a geometric frustrated system CdCr2O4 that upon cooling undergoes a spin-Peierls phase transition at TN = 7.8 K from a cubic and paramagnetic to a tetragonal and Neel state. Phonon modes measured around Brillouin zone boundaries show energy shifts when the transition occurs. Our analysis shows that the shifting can be understood as the ordinary effects of the lowering of the crystal symmetry

Frege on the Generality of Logical Laws

Frege claims that the laws of logic are characterized by their “generality,” but it is hard to see how this could identify a special feature of those laws. I argue that we must understand this talk of generality in normative terms, but that what Frege says provides a normative demarcation of the logical laws only once we connect it with his thinking about truth and science. He means to be identifying the laws of logic as those that appear in every one of the scientific systems whose construction is the ultimate aim of science, and in which all truths have a place. Though an account of logic in terms of scientific systems might seem hopelessly antiquated, I argue that it is not: a basically Fregean account of the nature of logic still looks quite promising