Microsecond resolution of quasiparticle tunneling in the single-Cooper-pair-transistor

We present radio-frequency measurements on a single-Cooper-pair-transistor in which individual quasiparticle poisoning events were observed with microsecond temporal resolution. Thermal activation of the quasiparticle dynamics is investigated, and consequently, we are able to determine energetics of the poisoning and un-poisoning processes. In particular, we are able to assign an effective quasiparticle temperature to parameterize the poisoning rate.Comment: 4 pages, 4 fig

Effect of a home visit-based low vision rehabilitation intervention on visual function outcomes: an exploratory randomized controlled trial

Purpose: To examine the effect of a home visit–based visual rehabilitation intervention on: (1) self-reported visual function and (2) depression, wellbeing, loneliness, adjustment to visual loss, and generic health-related quality of life. Methods: In an exploratory, assessor-masked, individually randomized, single-center controlled trial, 67 participants (age: 75.22 ± 16.21 years) with low vision were allocated either to receive the home visit–based visual rehabilitation intervention (n = 35) or to a waiting list control arm (n = 32). Outcome measures were collected by telephone interview at baseline and 6 months later. The primary outcome measure was the 48-item Veterans Affairs Low Vision Visual Functioning Questionnaire (VA LV VFQ-48). Secondary outcome measures were: the Patient Health Questionnaire; the Warwick-Edinburgh Mental Well-being Scale, the Adjustment to Age-related Visual Loss Scale, the standardized health-related quality of life questionnaire, and the University of California, Los Angeles Loneliness Scale. Questionnaire scores at follow-up were analyzed using analysis of covariance, controlling for the baseline score and the variables, age, number of comorbidities, visual acuity, and baseline wellbeing score. Results: Visual function (VA LV VFQ-48) improved at follow-up in both groups, with a significantly greater improvement demonstrated by the intervention group (95% confidence interval, 0.33–0.68 logits, P = 0.031), with a moderate effect size (0.55). Secondary outcomes did not indicate any statistically significant differences between groups. Conclusions: The study provides preliminary evidence that a home visit–based visual rehabilitation intervention has a positive influence on vision-related functional outcomes. A larger trial with an expanded intervention to include a mental health component and cost-effectiveness analysis is needed

Development and operation of the twin radio frequency single electron transistor for solid state qubit readout

Ultra-sensitive detectors and readout devices based on the radio frequency single electron transistor (rf-SET) combine near quantum-limited sensitivity with fast operation. Here we describe a twin rf-SET detector that uses two superconducting rf-SETs to perform fast, real-time cross-correlated measurements in order to distinguish sub-electron signals from charge noise on microsecond time-scales. The twin rf-SET makes use of two tuned resonance circuits to simultaneously and independently address both rf-SETs using wavelength division multiplexing (WDM) and a single cryogenic amplifier. We focus on the operation of the twin rf-SET as a charge detector and evaluate the cross-talk between the two resonance circuits. Real time suppression of charge noise is demonstrated by cross correlating the signals from the two rf-SETs. For the case of simultaneous operation, the rf-SETs had charge sensitivities of $\delta q_{SET1} = 7.5 \mu e/\sqrt{Hz}$ and $\delta q_{SET2} = 4.4 \mu e/\sqrt{Hz}$.Comment: Updated version, including new content. Comments most welcome: [email protected] or [email protected]

Deed for sale from Davis Family to L. N. Box, H. Rutledge, and Nathaniel Jackson, 1878

From the Falcón Family Collection, contains personal, legal documents, photographs, family genealogy, and newspaper articles concerning various family members of the Falcón family. The largest of the series being that of correspondence between Clotilde Falcón and Alfredo Náñez. Deed for sale from Davis Family to L. N. Box, H. Rutledge, and Nathaniel Jackson, 1878, Container: 31, Box: 3, Folder: 126. University of Texas Rio Grande Valley Special Collections and Archives, Edinburg Campus. https://archives.lib.utrgv.edu/repositories/2/archival_objects/94842https://scholarworks.utrgv.edu/hidalgohist/1003/thumbnail.jp

HPV-Reactive T-Cell Receptor Expand in Combination Therapy

https://openworks.mdanderson.org/sumexp22/1001/thumbnail.jp

Development of an Augmented Reality Equipped Composites Bonded Assembly and Repair for Aerospace Applications

The prosperity of aircraft transportation together with revolutionary promotion of composite components used in commercial aircraft pose enormous challenges to the aircraft composite assembly and repair (especially uncertainties associated with polymer process parameters control, barely visible defects and non-destructive inspection capability to inspect zero-thickness defects). Therefore, an industry solution owning merits on reliability and repeatability of assembly process is at high demand. Augmented Reality (AR), a human computer interaction technology, possesses its exclusive superiority on its capability of inflicting digital mock-up into physical environment. The above property of AR provides colossal opportunities to be utilised into industrial applications to contribute the realisation of automated, efficient, streamlined and reliable process and assembly. The current ongoing research aims at developing an AR System integrated into aircraft composite bonded assembly and repair as a guidance tool to instruct technicians’ repairing operation, mitigate human errors, and reduce duration of repair and assembly. Upon the accomplishment of the System, the researchers would aim to investigate the incorporation of machine learning and deep network algorithms to enable and significantly improve the interactions between the multitude of process parameters involved in the composites assembly control procedures, solely relying upon the AR geometric data. This will ultimately lead to dramatic reduction of sensors in aircraft assembly, mitigation of in-process analysis time, reduction of process and post-process inspection time, and a higher quality assembly. Stepped scarf composite repair embedded with soft composite patches was selected as the archetype to be brought into effect though hard patches were partially examined as well. The AR System has focused on composite patches assembly and vacuum bagging process to address the predicament of miscellaneous steps and fibre directions

Persistence of DNA from laundered semen stains: Implications for child sex trafficking cases

In sexual assault cases, particularly those involving internal child sex trafficking (ICST), victims often hide their semen-stained clothing. This can result in a lag time of several months before the items are laundered and subsequently seized during a criminal investigation. Although it has been demonstrated previously that DNA can be recovered from clothing washed immediately after semen deposition, laundered items of clothing are not routinely examined in ICST cases, due to the assumption that the time delay and washing would result in no detectable DNA. The aim of this study was to examine whether viable DNA profiles could be recovered from laundered semen stains where there has been a significant lag time between semen deposition from one or more individuals and one or more washes of the stained clothing. Items of UK school uniform (T-shirts, trousers, tights) were stained with fresh semen (either from a single donor or a 1:1 mixture from two donors) and stored in a wardrobe for eight months. Stained and unstained items (socks) were then washed at 30°C or 60°C and with non-biological or biological detergent. DNA samples extracted from the semen-stained sites and from the unstained socks were quantified and profiled. High quantities of DNA, (6-18μg) matching the DNA profiles of the semen donors, were recovered from all semen-stained clothing that had been laundered once, irrespective of wash conditions. This quantity,and profile quality,did not decline significantly with multiple washes. The two donor semen samples yielded ∼10-fold more DNA from the T-shirts than from the trousers. This disparity resulted in the T-shirts yielding a ∼1:1 mixture of DNA from the two donors, whereas the trousers yielded a major DNA profile matching only that of the second donor. The quantities of DNA recovered from the unstained socks were an order of magnitude lower, with most of the DNA being attributable to the donor of the semen on the stained clothing within the same wash, demonstrating the transfer of semen-derived DNA among items of clothing in the washing machine. This study demonstrates that complete DNA profiles can be obtained from laundered semen stains on school uniform-type clothing, with an eight-month lag time between semen deposition and laundering, despite multiple washes and stains from two semen donors. These data emphasise the need to recover and examine the clothing of victims for semen and DNA evidence, even if the clothing has been stored for several months or washed multiple times since the sexual offence took place