The New Testament Teaches Planned Giving

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Evaluation of composting latrines

This paper presents the interim findings of a sanitation research project, undertaken in an urban informal settlement, with the support of the Greater Johannesburg Transitional Metropolitan Council (GJMC) and the Water Research Commission. A locally developed comporting latrine called the “Enviro Loo” is being evaluated in terms of health impacts and technical performance. Thirty comporting latrines were installed in the Elias Motswaledi settlement, south of Johannesburg, for trial use and monitoring over a period of one year. Results of the monitoring and the acceptability of these latrines as compared to a control group of thirty communal chemical latrine users, is discussed

Recognition without identification, erroneous familiarity, and déjà vu

Déjà vu is characterized by the recognition of a situation concurrent with the awareness that this recognition is inappropriate. Although forms of déjà vu resolve in favor of the inappropriate recognition and therefore have behavioral consequences, typical déjà vu experiences resolve in favor of the awareness that the sensation of recognition is inappropriate. The resultant lack of behavioral modification associated with typical déjà vu means that clinicians and experimenters rely heavily on self-report when observing the experience. In this review, we focus on recent déjà vu research. We consider issues facing neuropsychological, neuroscientific, and cognitive experimental frameworks attempting to explore and experimentally generate the experience. In doing this, we suggest the need for more experimentation and amore cautious interpretation of research findings, particularly as many techniques being used to explore déjà vu are in the early stages of development.PostprintPeer reviewe

The role of perceived environment, neighbourhood characteristics, and attitudes in walking behaviour: evidence from a rapidly developing city in China

The associations between objective and subjective dimensions of the built environment and walking behaviour have been examined extensively in existing studies. However, the interaction effects of those dimensions of the built environment on walking behaviour are understudied and may be more complex than hitherto suggested. Apart from the subjective dimensions of the built environment, walking attitudes also play a role in moderating these relationships. This paper investigates the independent and joint effects of objective neighbourhood characteristics, people’s perceptions of the neighbourhood environment, and walking attitudes on the frequency of walking by using Shenzhen as a case study. Since those effects may vary across different kinds of walking trips, the analysis looks separately at three major types of walking at the neighbourhood level—walking for work/school, walking for leisure/recreation, and walking for household responsibilities. Logistic regression analyses confirm that the correlates of people’s walking frequency vary considerably among different types of walking. Statistically significant interaction effects of objective neighbourhood characteristics and perceived environment are found. The results suggest that positive perceptions of the environment can compensate for the effect that low objective walkability of neighbourhoods has on people’s walking frequency. When seeking to encouraging walking at the neighbourhood level, policymakers should not only concentrate on improving objective neighbourhood characteristics but also consider people’s perception of the neighbourhood environment and their attitudes towards walking

Comparative evaluation of three TSPO PET radiotracers in a LPS-induced model of mild neuroinflammation in rats.

PURPOSE: Over the past 20 years, neuroinflammation (NI) has increasingly been recognised as having an important role in  many neurodegenerative diseases, including Alzheimer's disease. As such, being able to image NI non-invasively in patients is critical to monitor pathological processes and potential therapies targeting neuroinflammation. The translocator protein (TSPO) has proven a reliable NI biomarker for positron emission tomography (PET) imaging. However, if TSPO imaging in acute conditions such as stroke provides strong and reliable signals, TSPO imaging in neurodegenerative diseases has proven more challenging. Here, we report results comparing the recently developed TSPO tracers [(18)F]GE-180 and [(18)F]DPA-714 with (R)-[(11)C]PK11195 in a rodent model of subtle focal inflammation. PROCEDURES: Adult male Wistar rats were stereotactically injected with 1 μg lipopolysaccharide in the right striatum. Three days later, animals underwent a 60-min PET scan with (R)-[(11)C]PK11195 and [(18)F]GE-180 (n = 6) or [(18)F]DPA-714 (n = 6). Ten animals were scanned with either [(18)F]GE-180 (n = 5) or [(18)F]DPA-714 (n = 5) only. Kinetic analysis of PET data was performed using the simplified reference tissue model (SRTM) with a contralateral reference region or a novel data-driven input to estimate binding potential BPND. Autoradiography and immunohistochemistry were performed to confirm in vivo results. RESULTS: At 40-60 min post-injection, [(18)F]GE-180 dual-scanned animals showed a significantly increased core/contralateral uptake ratio vs. the same animals scanned with (R)-[(11)C]PK11195 (3.41 ± 1.09 vs. 2.43 ± 0.39, p = 0.03); [(18)]DPA-714 did not (2.80 ± 0.69 vs. 2.26 ± 0.41). Kinetic modelling with a contralateral reference region identified significantly higher binding potential (BPND) in the core of the LPS injection site with [(18)F]GE-180 but not with [(18)F]DPA-714 vs. (R)-[(11)C]PK11195. A cerebellar reference region and novel data-driven input to the SRTM were unable to distinguish differences in tracer BPND. CONCLUSIONS: Second-generation TSPO-PET tracers are able to accurately detect mild-level NI. In this model, [(18)F]GE-180 shows a higher core/contralateral ratio and BPND when compared to (R)-[(11)C]PK11195, while [(18)F]DPA-714 did not

The neglected social dimensions to a vehicle-to-grid (V2G) transition: a critical and systematic review

Vehicle-to-grid (V2G) refers to efforts to bi-directionally link the electric power system and the transportation system in ways that can improve the sustainability and security of both. A transition to V2G could enable vehicles to simultaneously improve the efficiency (and profitability) of electricity grids, reduce greenhouse gas emissions for transport, accommodate low-carbon sources of energy, and reap cost savings for owners, drivers, and other users. To understand the recent state of this field of research, here we conduct a systematic review of 197 peer-reviewed articles published on V2G from 2015 to early 2017. We find that the majority of V2G studies in that time period focus on technical aspects of V2G, notably renewable energy storage, batteries, or load balancing to minimize electricity costs, in some cases including environmental goals as constraints. A much lower proportion of studies focus on the importance of assessing environmental and climate attributes of a V2G transition, or on the role of consumer acceptance and knowledge of V2G systems. Further, there is need for exploratory work on natural resource use and externalities, discourses and narratives as well as social justice, gender, and urban resilience considerations. These research gaps need to be addressed if V2G is to achieve the societal transition its advocates seek

Early detection of neovascular age-related macular degeneration : an economic evaluation based on data from the EDNA study

Funding: The project was funded by the National Institute for Health Research (NIHR) Health Technology Assessment Programme (grant number: 12/142/07) and will be published in full in Health Technology Assessment. The funder was not involved in the study design; in the collection, analysis and interpretation of the data; in the writing of the report; and in the decision to submit the paper for publication. The Health Services Research Unit (HSRU) and the Health Economics Research Unit (HERU) are core funded by the Chief Scientist Office of the Scottish Government Health and Social Care Directorate (HSRU/2021-2024, HERU/2021-2024).Peer reviewedPostprin

Building future societies? A brief analysis of Braga’s school bus project

This paper seeks to demonstrate the importance of implementing trans- port policies that meet home to school (and vice versa) mobility needs of children and young people. Over the last few years families’ mobility has been given increasing attention. One of the most investigated aspects is home to work mobil- ity. Nowadays there is an urgent need to study and propose intervention measures regarding children’s mobility to school. In fact, studies show that the car is the preferred mode of transportation in Portugal. This trend has undoubtedly negative social, environmental and health consequences. Based on an evaluation study on the School Bus project in Braga (a research- intervention activity of BUILD-Braga Urban Innovation Laboratory Demonstrator), this paper discusses the difficulties in implementing sustainable mobility initiatives, pointing out anticipatory mea- sures that can be taken in medium-sized cities in order to stop the expansion of children’s transportation by car, and give them back spaces in the cities.UIDB/00736/202

Successful ageing : perceptions of adults aged between 70 and 101 years

In this research, content analysis was employed to investigate older adults\u27 perceptions of successful aging and the relationship of these perceptions to definitions given in the literature to date. Participants were 18 males and 42 females between the ages of 70 and 101 years. Analyses revealed older adults mentioned only 1 or 2 criteria of successful aging if asked for a definition; however, when prompted, they rated almost all the criteria emerging from the literature as highly important. Participants reported adjusting to the situations they were in by compensating for losses that occurred and selecting activities that best suited their capabilities. Overall, older adults\u27 perceptions of successful aging were similar to aspects identified in the literature. Not all aspects, however, were seen as important by all participants, and only low to moderate correlations were found between some aspects of successful aging. (Contains 3 figures and 4 tables.)<br /