598 research outputs found

    T-cell cytotoxicity in the absence of viral protein synthesis in target cells

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    CYTOTOXIC T cells lyse only those virus infected target cells in vitro which express, in addition to the viral antigen(s), those K or D region products of the major histocompati-bility complex (MHC) which were present during anti-viral sensitisation in vivo. This 'associative recogniton' by cytotoxic T cells could reflect the interaction of two T-cell receptors with specificity for target K or D gene products and independently for the viral antigen, or one receptor with specificity for virally altered K or D region products (see ref. 1 and refs therein). There are various ways that the MHC antigens could be altered, including 'modification from within', where the virus modifies host protein synthesis by interfering with transcription2, translation or post-translational glycosylation; or 'modification from without' where enzymic or chemical alteration of cell membrane proteins are induced by virus activity at the cell surface. In this report we show that inactivated Sendai virus or isolated Sendai virus envelopes can serve to modify a cell and make it a specific target for Sendai-immune T-cell killing, thus excluding the possibility of 'modification from within' in this system

    A quantum mechanical description of the experiment on the observation of gravitationally bound states

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    Quantum states in the Earth's gravitational field were observed, when ultra-cold neutrons fall under gravity. The experimental results can be described by the quantum mechanical scattering model as it is presented here. We also discuss other geometries of the experimental setup which correspond to the absence or the reversion of gravity. Since our quantum mechanical model describes, particularly, the experimentally realized situation of reversed gravity quantitatively, we can practically rule out alternative explanations of the quantum states in terms of pure confinement effects.Comment: LaTeX, 10 pages, 4 figures, v2: references adde

    An adaptive inelastic magnetic mirror for Bose-Einstein condensates

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    We report the reflection and focussing of a Bose-Einstein condensate by a new pulsed magnetic mirror. The mirror is adaptive, inelastic, and of extremely high optical quality. The deviations from specularity are less than 0.5 mrad rms, making this the best atomic mirror demonstrated to date. We have also used the mirror to realize the analog of a beam-expander, producing an ultra-cold collimated fountain of matter wavesComment: 4 pages, 4 figure

    Quantum damping of position due to energy measurements

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    Quantum theory for measurements of energy is introduced and its consequences for the average position of monitored dynamical systems are analyzed. It turns out that energy measurements lead to a localization of the expectation values of other observables. This is manifested, in the case of position, as a damping of the motion without classical analogue. Quantum damping of position for an atom bouncing on a reflecting surface in presence of a homogeneous gravitational field is dealt in detail and the connection with an experiment already performed in the classical regime is studied. We show that quantum damping is testable provided that the same measurement strength obtained in the experimental verification of the quantum Zeno effect in atomic spectroscopy [W. M. Itano et al., Phys. Rev. A {\bf 41}, 2295 (1990)] is made available.Comment: 19 pages + 4 figures available upon request; Plain REVTeX; To be published in Phys. Rev.

    Quantum Revivals in Periodically Driven Systems close to nonlinear resonance

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    We calculate the quantum revival time for a wave-packet initially well localized in a one-dimensional potential in the presence of an external periodic modulating field. The dependence of the revival time on various parameters of the driven system is shown analytically. As an example of application of our approach, we compare the analytically obtained values of the revival time for various modulation strengths with the numerically computed ones in the case of a driven gravitational cavity. We show that they are in very good agreement.Comment: 14 pages, 1 figur

    Creating a low-dimensional quantum gas using dark states in an inelastic evanescent-wave mirror

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    We discuss an experimental scheme to create a low-dimensional gas of ultracold atoms, based on inelastic bouncing on an evanescent-wave mirror. Close to the turning point of the mirror, the atoms are transferred into an optical dipole trap. This scheme can compress the phase-space density and can ultimately yield an optically-driven atom laser. An important issue is the suppression of photon scattering due to ``cross-talk'' between the mirror potential and the trapping potential. We propose that for alkali atoms the photon scattering rate can be suppressed by several orders of magnitude if the atoms are decoupled from the evanescent-wave light. We discuss how such dark states can be achieved by making use of circularly-polarized evanescent waves.Comment: 8 pages, 4 figure

    Deconstructing Decoherence

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    The study of environmentally induced superselection and of the process of decoherence was originally motivated by the search for the emergence of classical behavior out of the quantum substrate, in the macroscopic limit. This limit, and other simplifying assumptions, have allowed the derivation of several simple results characterizing the onset of environmentally induced superselection; but these results are increasingly often regarded as a complete phenomenological characterization of decoherence in any regime. This is not necessarily the case: The examples presented in this paper counteract this impression by violating several of the simple ``rules of thumb''. This is relevant because decoherence is now beginning to be tested experimentally, and one may anticipate that, in at least some of the proposed applications (e.g., quantum computers), only the basic principle of ``monitoring by the environment'' will survive. The phenomenology of decoherence may turn out to be significantly different.Comment: 13 two-column pages, 3 embedded figure

    Substrate-based atom waveguide using guided two-color evanescent light fields

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    We propose a dipole-force linear waveguide which confines neutral atoms up to lambda/2 above a microfabricated single-mode dielectric optical guide. The optical guide carries far blue-detuned light in the horizontally-polarized TE mode and far red-detuned light in the vertically-polarized TM mode, with both modes close to optical cut-off. A trapping minimum in the transverse plane is formed above the optical guide due to the differing evanescent decay lengths of the two modes. This design allows manufacture of mechanically stable atom-optical elements on a substrate. We calculate the full vector bound modes for an arbitrary guide shape using two-dimensional non-uniform finite elements in the frequency-domain, allowing us to optimize atom waveguide properties. We find that a rectangular optical guide of 0.8um by 0.2um carrying 6mW of total laser power (detuning +-15nm about the D2 line) gives a trap depth of 200uK for cesium atoms (m_F = 0), transverse oscillation frequencies of f_x = 40kHz and f_y = 160kHz, collection area ~ 1um^2 and coherence time of 9ms. We discuss the effects of non-zero m_F, surface interactions, heating rate, the substrate refractive index, and the limits on waveguide bending radius.Comment: 12 pages, 4 figures, revtex, submitted to Phys. Rev. A Replaced: final version accepted by PRA v.61 Feb 2000. (2 paragraphs added

    Fractional quantum revivals in the atomic gravitational cavity

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    In this paper we discuss the quantum dynamics and fractional quantum revivals of an integrable nonlinear system, consisting of an atom bouncing vertically from an evanescent field, for two cases with the simplified infinite-potential and the more practical exponential potential, respectively. We study the two cases separately, then contrast and compare the results and reach the conclusion that provided the starting position of the atoms is not too close to the reflecting surface supporting the evanescent wave (this condition is always satisfied in present experiments in this field), the two cases will produce the same results. This means that the idealized infinite potential is a good approximation to the more realistic exponential potential. Because the quantum analysis of the infinite-potential case is quite simple and straighforward (since its Schrödinger equation has analytical solutions), this will greatly simplify the quantum analysis of the more complicated exponential potential case and hence has practical significance
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