An experimental and theoretical aided 2D MoS2 nanoflowers strategy for rapid visual sensing of Gallic acid in food and clinical matrixes

This is the final version. Available on open access from Elsevier via the DOI in this recordData availability: No data was used for the research described in the article.Gallic acid (GA), an important phenolic component, is gaining popularity due to its biological and industrial applications. However, its rapid expansion can be hazardous, causing cancer and gene damage, making the design of a low-cost and fast GA sensor difficult. We used a single-step hydrothermal approach to synthesize MoS2 nanoparticles for colorimetric detection of GA. The nanoparticles were analyzed using techniques like; UV–Vis spectroscopy, FT-IR spectroscopy, SEM, EDX and XRD. The optimization of key parameters such as MoS2 concentration (2.0 mg), temperature (30 °C), and pH (7) resulted in a limit of detection (LOD) of 0.125 × 10−6 M with a dynamic range of 0.5 to 36 × 10−6 M. MoS2 nanoflowers performed as nanozymes in the filter paper-based sensor, catalyzing 3, 3′, 5, 5′-tetramethylbenzidine (TMB) oxidation, while GA acted as an inhibitor to prevent further reaction progression. The detection was made feasible through capturing an image support by an ordinary smartphone and the steady-state kinetic study validated MoS2 nanoflowers' affinity for sensing H2O2. The sensor performed well in real-world samples such as diet tea, green tea, water, blood serum, and urine, with recovery rates ranging from 93.2 % to 102.1 %. Density functional theory calculations were applied to provide an insight into GA-MoS2 binding interactions and changes in electronic properties. With all of these merits, we believe MoS2 nanoparticles can provide low-cost and portable filter paper-based strips as a sensing platform for visual assessment of GA

Impact of the Coronavirus Pandemic (COVID-19) Lockdown on Mental Health and Well-Being in the United Arab Emirates

United Arab Emirates (UAE) has taken unprecedented precautionary measures including complete lockdowns against COVID-19 to control its spread and ensure the well-being of individuals. This study investigated the impact of COVID-19 and societal lockdown measures on the mental health of adults in the UAE. A cross-sectional study was conducted using an English and Arabic online questionnaire between May and June 2020. The psychological impact was assessed by the Impact of Event Scale-Revised (IES-R), and the social and family support impact was evaluated using questions from the Perceived Support Scale (PSS). A total of 4,426 participants (3,325 females and 1,101 males) completed the questionnaire. The mean IES-R score was 28.0 ± 14.6, reflecting a mild stressful impact with 27.3% reporting severe psychological impact. Over 36% reported increased stress from work, home and financial matters. Also, 43–63% of the participants felt horrified, apprehensive or helpless due to COVID-19. Females, younger participants, part-timers, and college or University graduates were more likely to have a high IES-R score (p \u3c 0.05). The majority of participants reported receiving increased support from family members, paying more attention to their mental health, and spending more time to rest and relax. The results of this study demonstrate the impact of the COVID-19 pandemic on mental health among the UAE residents and highlight the need to adopt culturally appropriate interventions for the general population and vulnerable groups, such as females and younger adults

Identification of GBV-D, a Novel GB-like Flavivirus from Old World Frugivorous Bats (Pteropus giganteus) in Bangladesh

Bats are reservoirs for a wide range of zoonotic agents including lyssa-, henipah-, SARS-like corona-, Marburg-, Ebola-, and astroviruses. In an effort to survey for the presence of other infectious agents, known and unknown, we screened sera from 16 Pteropus giganteus bats from Faridpur, Bangladesh, using high-throughput pyrosequencing. Sequence analyses indicated the presence of a previously undescribed virus that has approximately 50% identity at the amino acid level to GB virus A and C (GBV-A and -C). Viral nucleic acid was present in 5 of 98 sera (5%) from a single colony of free-ranging bats. Infection was not associated with evidence of hepatitis or hepatic dysfunction. Phylogenetic analysis indicates that this first GBV-like flavivirus reported in bats constitutes a distinct species within the Flaviviridae family and is ancestral to the GBV-A and -C virus clades

Evaluation de l'appui à l'ajustement structurel de la Commission Européenne au Cameroun

Ce rapport établi pour le compte de la Commission des Communautés Européennes développe les points suivants : l'historique des programmes d'ajustement structurel, l'appui à l'ajustement structurel de la C.E., la pertinence du programme et l'éligibilité du Cameroun à l'AAS de la communauté, l'impact des politiques d'ajustement structurel, l'impact des AAS de la communauté et le niveau d'attente des objectifs spécifiques de la C.E. (efficacité), l'efficience et la viabilité. En conclusion de cette évaluation, les auteurs font état d'un certains nombre de recommandations tirer pour la C.

World Allergy Organization Study on Aerobiology for Creating First Pollen and Mold Calendar With Clinical Significance in Islamabad, Pakistan; A Project of World Allergy Organization and Pakistan Allergy, Asthma & Clinical Immunology Centre of Islamabad

Pollen and mold allergies are highly problematic in Islamabad. This study was conducted to investigate the type and concentration of airborne pollens/molds causing allergic diseases in susceptible individuals. A volumetric spore trap (Burkard) was placed at the height of 11 m and ran continuously for 3 years. Once a week, the collecting drum was prepared by affixing Melinex tape with a double sided adhesive that was coated with a thin layer of silicone grease. Every Sunday at 9:00 AM the drum was replaced by another drum and the pollen/mold spores were removed and permanently mounted on slides. Using a microscope, the trapped particles were identified and recorded as counts per cubic meter of air per hour. From these data, the pollen and mold calendars were constructed and expressed as counts per cubic meter of air per day. Skin prick tests were performed on more than 1000 patients attending the Pakistan Allergy, Asthma & Clinical Immunology Centre of Islamabad. The results indicated that there were 2 main pollen plants that contributed to seasonal allergies. These were Broussonetia papyrifera and Cannabis sativa during the March/April season and the July/September season, respectively. Although mold spores were continuously detected throughout the year, the most prominent mold was undetected mold and unconfirmed mold species similar to Stachybotrys species, which was high from July to September/October. Two additional molds contributing to allergic reactions were Pithomyces species and Cladosporium species, which were active during January and April, with the latter also being detected between October and November. These results may prove beneficial to both patients and physicians in planning a therapeutic protocol for avoidance and amelioration. Keywords: pollen and mold calendar, aerobiology, Islamabad, Burkard spore trap, Broussonetia papyrifera, Cannabis sativa, skin prick test, SPT, asthma, allergic rhiniti