Molecular epidemiology and genotype distribution of Human Papillomavirus (HPV) among Arab women in the state of Qatar

Background: Human Papilloma Virus (HPV) infection is the major cause of cervical cancer worldwide. With limited data available on HPV prevalence in the Arab countries, this study aimed to identify the prevalence and genotypic distribution of HPV in the State of Qatar. Methods: 3008 cervical samples, exclusively of women with Arabic origin residing in Qatar were collected from the Women’s Hospital and Primary Health Care Corporation in Doha, State of Qatar. HPV DNA detection was done using GP5+/6+ primers based real time-polymerase chain reaction (RT-PCR) assay followed by the usage of HPV type specific primers based RT- PCR reactions and Sanger sequencing for genotype identification. Results: Similar prevalence rates of HPV infection was identified in both Qatari and non-Qatari women at 6.2% and 5.9% respectively. HPV prevalence rate of 5.8% and 18.4% was identified in women with normal cytology and in women with abnormal cytology respectively. HPV 81, 11 and 16, in decreasing order were the most commonly identified genotypes. HPV 81 was the most frequent low-risk genotype among women with both normal (74.0%) and abnormal (33.3%) cytology. HPV 16 (4.6%) was identified as the predominant high-risk HPV genotype among women with normal cytology and HPV 16, HPV 18, and HPV 56 (22.2% each) were the most common identified high-risk genotypes in women with abnormal cytology Conclusions: The overall HPV prevalence in Arab women in Qatar was identified as 6.1% with an increased HPV prevalence seen in women with abnormal cytology results and no significant trends seen with age. In contrast to Western countries, we report a varied genotypic profile of HPV with a high prevalence of low-risk HPV genotype 81 among the Arab women residing in Qatar.Weill Cornell Medical College in Qatar; and by a grant from the Qatar National Research Fund (NPRP- 09-344-3-082)

Elastic properties of TeO2-B2O3-Ag2O glasses.

A series of glasses [(TeO2) x (B2O3)1−x ]1−y [Ag2O] y with x = 70 and y = 10, 15, 20, 25 and 30 mol% were synthesised by rapid quenching. Longitudinal and shear ultrasonic velocity were measured at room temperature and at 5 MHz frequency. Elastic properties, Poisson's ratio, microhardness, softening temperature and Debye temperature have been calculated from the measured density and ultrasonic velocity at room temperature. The experimental results indicate that the elastic constants depend upon the composition of the glasses and the role of the Ag2O inside the glass network is discussed. Estimated parameters based on Makishima–Mackenzie theory and bond compression model were calculated in order to analyse the experimental elastic moduli. Comparison between the experimental elastic moduli data obtained in the study and the calculated theoretically by the mentioned above models has been discussed

Cystic Duct Cholangiography

A series of 837 cystic duct cholangiograms has been reviewed. The technique is simple and safe to carry out. It is not time consuming and does not require any unusual equipment. It has reduced the incidence of common duct exploration and has decreased the incidence of retained common duct stones. It is stressed that, unless the operative cholangiogram fulfills the criteria of a normal cholangiogram, especially in relation to size and tapering of the tower end of the duct, then common duct exploration should be earned out. Its almost routine use can only increase the general quality and accuracy of biliary tract surgery

Mapping and Review of Resources for, and Needs of Vulnerable and Marginalised Young People in the Asia Pacific Region on Digital Literacy, Safety and Participation

This report presents findings from the ‘Mapping and review of online resources for, and perceived needs among vulnerable and marginalized young people in the Asia-Pacific region on digital literacy, safety and participation’ commissioned by UNESCO and UNDP. This rapid assessment aims to understand the needs of LGBTI young people and Young Key Populations (YKP) in the AIDS response in the Asia-Pacific region, in their quest for more secure digital spaces and improved experiences of digital citizenship. The assessment will also act as key guidance material for Youth-led organizations (Youth Lead and Y-Peer) to develop their own tools and resources for their communities and support grassroot level organizations to build online platforms for advocacy. Findings from this assessment will inform follow-up action by UNDP and UNESCO, to close the gap on available and appropriate online digital citizenship resources and capacity-building opportunities for these groups