Coxsackie B2 Virus Infection Causing Multiorgan Failure and Cardiogenic Shock in a 42-Year-Old Man

Infections from coxsackie B2 viruses often cause viral myocarditis and, only rarely, multisystem organ impairment. We present the unusual case of a 42-year-old man in whom coxsackie B2 virus infection caused multiorgan infection, necessitating distal pancreatectomy, splenectomy, renal dialysis, and venoarterial extracorporeal membrane oxygenation with mechanical ventilation. In addition, the patient had a rapid-eye-movement sleep-related conduction abnormality that caused frequent sinus pauses of longer than 10 s, presumably due to myocarditis from the coxsackievirus infection. He recovered after permanent pacemaker placement and was discharged from the hospital. We discuss our aggressive supportive care and the few other reports of multiorgan impairment from coxsackieviruses

Heritability estimates of hatching time in the fayoumi chickens

International audienc

InVitro-Q: A High-throughput Biosensor Used to Evaluate the Mechanism of Phagocytosis of Macrophages Using Different Particles

The method of phagocytosis of a particle can provide information on how macrophages respond to a detected particle. The response elicited varies based on the nature of the particle and in turn changes which receptor-mediated phagocytosis is initiated. We have developed a multi-well cell-based sensor that can monitor real-time biological changes in living cells, such as mass redistribution, and viscoelasticity. This system provides unique kinetic information regarding the phenotypic change in the cells post treatment. As a proof of principle study, we evaluate macrophage phagocytosis using three different particles: latex beads, Zymosan A, and Staphylococcus aureus. These studies show the InVitro-Q’s ability to distinguish and differentiate the unique physiological method of macrophage phagocytosis of an indigestible particle (latex beads), and digestible particles of different origins (Zymosan A (yeast cell wall) and S. aureus (wood bacteria). The real-time data generated illustrates the unique phenotypic signatures of macrophages in response to particle specific phagocytosis. The traces then dictate time points at which visualization will occur, and guides the elucidation of the mechanism of action

DFIG fault ride through improvement during VSC faults

The sensitivity of the doubly fed induction generator (DFIG) to external faults has motivated researchers to investigate the impact of various grid disturbances such as voltage sag and short circuit faults on the fault ride through (FRT) capability of the DFIG. However, no attention has been given to the impact of internal faults within voltage source converters (VSCs) that interface the DFIG with the grid, on the dynamic performance of the machine. This paper investigates the impact of various VSC faults on the dynamic performance and the FRT capability of the DFIG. Faults such as fire-through and flashover within the VSC switches are considered in this paper. Moreover, faults across the DC-link capacitor are included in this study as a common problem in the VSCs. The impact of these faults when they occur within the grid side converter (GSC) and rotor side converter (RSC) are investigated. A proper STATCOM controller to mitigate the effects of these faults on the FRT is proposed. The DFIG compliance with numerous and recently released FRT grid codes under these faults with and without the STATCOM are examined and compared. Furthermore, the capability of a proposed controller to bring the voltage profile at the point of common coupling (PCC) to the nominal steady-state level under five possible VSC faults cases is examined. The proposed controller is efficient, simple, and easy to implement

Estimation of general and specific combining abilities from a diallel cross of three inbred lines of Fayoumi chicks

International audienc

Coxsackie B2 Virus Infection Causing Multiorgan Failure and Cardiogenic Shock in a 42-Year-Old Man

Infections from coxsackie B2 viruses often cause viral myocarditis and, only rarely, multisystem organ impairment. We present the unusual case of a 42-year-old man in whom coxsackie B2 virus infection caused multiorgan infection, necessitating distal pancreatectomy, splenectomy, renal dialysis, and venoarterial extracorporeal membrane oxygenation with mechanical ventilation. In addition, the patient had a rapid-eye-movement sleep-related conduction abnormality that caused frequent sinus pauses of longer than 10 s, presumably due to myocarditis from the coxsackievirus infection. He recovered after permanent pacemaker placement and was discharged from the hospital. We discuss our aggressive supportive care and the few other reports of multiorgan impairment from coxsackieviruses

Heterosis in Fayoumi strain incrossing

International audienc