Health (including Clinical Studies)

Politics, science, research and the public base their discussions on comprehensive, valid and systematic health care data. Data based information is needed in order to measure the results or success of a policy of procedure. In Germany, the Information System of the Federal Health Monitoring (IS-GBE) comprises of a comprehensive health system data collection. Currently, the information system contains health data and information from over a 100 different sources, for instance surveys done by the statistical offices of the federation or the Länder, as well as many other surveys done within the health care system. Apart from the IS-GBE additional official and non-official health care data sources exist in Germany. Within this expertise changes made from 2001 on to existing health data sources as well as newly established data sources are presented. Data sources dealt with in other expertise are not considered. The up until now one time insuree sample collected in 2001 was, for example, collected in the course of the reform of the risk structure adjustment within the statutory health insurance is one of the more recent samples. From our point of view we highly recommend an update of this representative sample.Information System of the Federal Health Monitoring (IS-FHM), Microcensus, Inpatient Diagnosis Data, Hospital statistics by Diagnosis Related Groups (DRG Statistics), Cancer Registries, Kidney Replacement Therapy Statistics (QuaSi Niere), External Comparative Quality Assurance of the In-patient Sector (BQS), Structured Reports on Quality (SQB), Compulsory Health Insurance (CHI) Claims Data: Insuree Sample, GEK Claims Data

Freie Fahrt für die Versorgungsforschung?

Zu Vergangenheit, Gegenwart und Zukunft der Nutzung der GKV-Routinedaten für die Versorgungsforschung: Für die Versorgungsforschung, aber auch für viele andere Beteiligte, die im und für das Gesundheitswesen tätig sind, sind Zugang und Verfügbarkeit natürlich in besonderer Weise wichtig. Das noch von der Vorgängerregierung verabschiedete „Datennutzungsgesetz“ (DNG) (Bundesministerium der Justiz 2021) hat hierzu den Stein ins Rollen gebracht, unter anderem den Begriff der „Forschungsdaten“ eingeführt, aber letztlich mehr Fragen aufgeworfen, als dass brauchbare Regulierungen dabei herausgekommen sind

Influence on persistence and adherence with oral bisphosphonates on fracture rates in osteoporosis

Background and Aim: Oral bisphosphonates have been shown to reduce the risk of fractures in patients with osteoporosis. It can be assumed that the clinical effectiveness of oral bisphosphonates depends on persistence with therapy. Methods: The influence of persistence with and adherence to oral bisphosphonates on fracture risk in a real-life setting was investigated. Data from 4451 patients with a defi ned index prescription of bisphosphonates were included. Fracture rates within 180, 360, and 720 days after index prescription were compared between persistent and non-persistent patients. In an extended Cox regression model applying multiple event analysis, the influence of adherence was analyzed. Persistence was defined as the duration of continuous therapy; adherence was measured in terms of the medication possession ratio (MPR). Results: In patients with a fracture before index prescription, fracture rates were reduced by 29% (p = 0.025) comparing persistent and non-persistent patients within 180 days after the index prescription and by 45% (p < 0.001) within 360 days. The extended Cox regression model showed that good adherence (MPR ≥ 0.8) reduced fracture risk by about 39% (HR 0.61, 95% CI 0.47–0.78; p < 0.01). Conclusions: In patients with osteoporosis-related fractures, good persistence and adherence to oral bisphosphonates reduced fracture risk significantly

Health (including Clinical Studies)

Politics, science, research and the public base their discussions on comprehensive, valid and systematic health care data. Data based information is needed in order to measure the results or success of a policy of procedure. In Germany, the Information System of the Federal Health Monitoring (IS-GBE) comprises of a comprehensive health system data collection. Currently, the information system contains health data and information from over a 100 different sources, for instance surveys done by the statistical offices of the federation or the Länder, as well as many other surveys done within the health care system. Apart from the IS-GBE additional official and non-official health care data sources exist in Germany. Within this expertise changes made from 2001 on to existing health data sources as well as newly established data sources are presented. Data sources dealt with in other expertise are not considered. The up until now one time insuree sample collected in 2001 was, for example, collected in the course of the reform of the risk structure adjustment within the statutory health insurance is one of the more recent samples. From our point of view we highly recommend an update of this representative sample