Computer Tomograph Measurements in Shear and Gravity Particle Flows

The paper reports the recent results obtained on the applicability of cross-sectional digital imaging method to study particle flow characteristics in 3D particle beds forced to move by gravity or shear. X-ray CT imaging technique is widely used in medical diagnostics and, during the last decades, its spatial and temporal resolution has been improved significantly. In this study, an attempt was made to use this technique for engineering purposes. Two experimental set-ups with different types of particle flows were investigated using Siemens Somatom Plus type CT equipment. A series of trials were carried out in a small model hopper with flat bottom and almost cylindrical side wall slightly deviating from verticality. Non steady-state flow was studied during the outflow of particulate material from this vessel, through a central hole at the bottom. Further investigation was fulfilled in a modified Cuette-type shearing device to study steady-state shear flow. This equipment consisted of an almost cylindrical vessel identical to that used for gravity flow measurements, and a smaller inner cylinder rotating within this vessel concentrically, around its vertical axis. The surface of the inner cylinder was notched vertically, i.e. perpendicularly to the direction of rotation to increase wall friction between the particles and the cylinder. Almost spherical sucrose granules, also used for gravity flow measurements, were filled into the gap between the rotating cylinder and the outer wall of the equipment. Movement of particles took place due to shear, generated within the particle bed. By using X-ray CT technique, cross-sectional digital images were obtained in every two seconds for both types of particle flows. For this, the cross-sectional variation of the local Hounsfield density values were measured in a matrix of 0.1x0.1x2.0 mm space elements. It was proved that the applied non-invasive crosssectional imaging technique was suitable to distinguish the stationary and moving particle regions, and by this, to estimate the location of the boundary zone between them

Deviation from the Fourier law in room-temperature heat pulse experiments

We report heat pulse experiments at room temperature that cannot be described by Fourier's law. The experimental data is modelled properly by the Guyer--Krumhansl equation, in its over-diffusion regime. The phenomenon is due to conduction channels with differing conductivities, and parallel to the direction of the heat flux.Comment: 9 pages, 4 figure

Poloxamers for Surface Modification of Hydrophobic Drug Carriers and Their Effects on Drug Delivery

Tri-block copolymer poloxamers are successfully employed for reducing adsorption of proteinous molecules onto hydrophobic surfaces, which will protect them from quick engulfing by macrophages. For sustained systemic circulation of hydrophobic drug carriers, particle surfaces need suitable modification for avoiding phagocytosis and this can be successfully done by poloxamers. They can affect the drug release profile, which makes them a very promising agent for targeted delivery. This review discusses the structure, characteristics and advantages of poloxamers. Poloxamer adsorption onto hydrophobic surfaces and adlayer thickness, relative phagocytic uptake and drug release profiles of coated drug loaded particles have been described in detail

Quasiparticle Interference on the Surface of Topological Crystalline Insulator Pb(1-x)Sn(x)Se

Topological crystalline insulators represent a novel topological phase of matter in which the surface states are protected by discrete point group-symmetries of the underlying lattice. Rock-salt lead-tin-selenide alloy is one possible realization of this phase which undergoes a topological phase transition upon changing the lead content. We used scanning tunneling microscopy (STM) and angle resolved photoemission spectroscopy (ARPES) to probe the surface states on (001) Pb$_{1-x}$Sn$_{x}$Se in the topologically non-trivial (x=0.23) and topologically trivial (x=0) phases. We observed quasiparticle interference with STM on the surface of the topological crystalline insulator and demonstrated that the measured interference can be understood from ARPES studies and a simple band structure model. Furthermore, our findings support the fact that Pb$_{0.77}$Sn$_{0.23}$Se and PbSe have different topological nature.Comment: 5 pages, 4 figure

Borehole-wall scanning for Mars research – testing the ExoMars 2020 rover’s work at Tabernas Desert

Overview of the borehole-wall scanning results from the ExoFIT field test of the ExoMars 2020 rover in Tabernas Desert, Spain

Co-encapsulation of human serum albumin and superparamagnetic iron oxide in PLGA nanoparticles: Part II. Effect of process variables on protein model drug encapsulation efficiency.

This study investigates encapsulation efficiency of model drug, encapsulated by magnetic poly d,l-lactic-co-glycolic acid (PLGA) nanoparticles (NPs). This is the following part of our preceding paper, which is referred in this paper as Part I. Magnetic nanoparticles and model drug human serum albumin (HSA)-loaded PLGA NPs were prepared by the double emulsion solvent evaporation method. Among five important process variables, concentration of PLGA and concentration of HSA in the inner aqueous phase along with their cross-effect had the strongest influence on the encapsulation efficiency. Encapsulation efficiency of nanoparticles ranged from 18% to 97% depending on the process conditions. Higher encapsulation efficiencies can be achieved by using low HSA and high PLGA concentrations. The optimization process, carried out by exact mathematical tools using GAMSTM/MINOS software makes it easier to find out optimum process conditions to achieve comparatively high encapsulation efficiency (e.g. 92.3%) for relatively small-sized PLGA NPs (e.g. 155 nm)

Bulk crystal growth and electronic characterization of the 3D Dirac Semimetal Na3Bi

High quality hexagon plate-like Na3Bi crystals with large (001) plane surfaces were grown from a molten Na flux. The freshly cleaved crystals were analyzed by low temperature scanning tunneling microscopy (STM) and angle-resolved photoemission spectroscopy (ARPES), allowing for the characterization of the three-dimensional (3D) Dirac semimetal (TDS) behavior and the observation of the topological surface states. Landau levels (LL) were observed, and the energy-momentum relations exhibited a linear dispersion relationship, characteristic of the 3D TDS nature of Na3Bi. In transport measurements on Na3Bi crystals the linear magnetoresistance and Shubnikov-de Haas (SdH) quantum oscillations are observed for the first time.Comment: To be published in a special issue of APL Material