297 research outputs found
An Esophageal Leiomyoma Mistaken as an Esophageal Duplication Cyst
Esophageal leiomyoma is a benign tumor that accounts for two-thirds of esophageal benign tumors. In general, patients with esophageal leiomyoma are asymptomatic; however, as the tumor grows in size, symptoms such as dysphagia, chest discomfort, obstruction, or bleeding can appear. A 65-year-old man visited our clinic to receive treatment for a subepithelial tumor in the lower esophagus, which was incidentally found during endoscopy for work-up of chest discomfort and indigestion. On endoscopic ultrasonography (EUS), the tumor was 2.6Ă—1.9 cm in size, with a cystic lesion located in the submucosal and proper muscle layers and thick cystic wall. Therefore, it was highly likely to be a duplication cyst. As the patient had symptoms such as chest discomfort, surgical resection was performed. The tumor was finally diagnosed as a leiomyoma with cystic degeneration. Leiomyoma with cystic change that has similar EUS features to duplication cyst is rare. Thus, we report the case with a literature review
WSPMaker: a web tool for calculating selection pressure in proteins and domains using window-sliding
Freshwater and Terrestrial Algae from Ny-Ålesund and Blomstrandhalvøya Island (Svalbard)
A field survey of algae and cyanobacteria from terrestrial and freshwater habitats in the vicinity of Ny-Ålesund and on Blomstrandhalvøya Island (Svalbard) was performed in June 2009, and results were compared with data from our fieldwork in June 2006. In total, we identified 30 taxa belonging to 23 genera from the specimens collected near Ny-Ålesund (26 taxa) and on Blomstrandhalvøya Island (24 taxa). Five species previously unrecorded from this locality are depicted, including astaxanthin-containing Haematococcus sp. collected from Blomstrandhalvøya Island. This is the first report on a Haematococcus species from the High Arctic.Une étude sur le terrain portant sur les algues et les cyanobactéries d’habitats terrestres et dulçaquicoles dans les environs de Ny-Ålesund et de l’île Blomstrandhalvøya (Svalbard) a été réalisée en juin 2009, et les résultats ont été comparés aux données de notre travail sur le terrain effectué en juin 2006. En tout, nous avons identifié 30 taxons appartenant à 23 genres à partir de spécimens prélevés près de Ny-Ålesund (26 taxons) et de Blomstrandhalvøya (24 taxons). Cinq espèces qui n’avaient jamais été répertoriées dans cette localité sont illustrées, dont l’Haematococcus sp. contenant de l’astaxanthine recueillie à l’île Blomstrandhalvøya. Il s’agit de la première fois que l’espèce Haematococcus a été signalée dans l’Extrême-Arctique
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Atrophic Gastritis: A Related Factor for Osteoporosis in Elderly Women
Purpose Osteoporosis poses a great threat to the aging society. Hypochlorhydric or achlorhydric conditions are risk factors for osteoporosis. Atrophic gastritis also decreases gastric acid production; however, the role of atrophic gastritis as a related factor for osteoporosis is unclear. We investigated the relationship between atrophic gastritis and osteoporosis in postmenopausal women over 60 years of age. Subjects and Methods A total of 401 postmenopausal women were included in this cross-sectional study, which was conducted during their medical check-ups. Bone mineral densitometry was measured using a dual energy X-ray absorptiometry. Atrophic gastritis was defined endoscopically if gastric mucosa in the antrum and the body were found to be atrophied and thinned and submucosal vessels could be well visualized. Results: The proportion of people with atrophic gastritis was higher in the osteoporotic group than in the group without osteoporosis. A linear relationship was observed in the proportion of atrophic gastritis according to the categories of normal, osteopenia, and osteoporosis at the lumbar spine (p for trend = 0.039) and femur (p for trend = 0.001). A multiple logistic regression analysis revealed that the presence of atrophic gastritis was associated with an increased odds of osteoporosis after adjusting for age, body mass index, triglyceride, high-density lipoprotein cholesterol, alcohol consumption, and smoking status (odds ratio 1.89, 95% confidence interval 1.15–3.11). Conclusions: Atrophic gastritis is associated with an increased likelihood of osteoporosis in Korean elderly women
Methotrimeprazine-induced Corneal Deposits and Cataract Revealed by Urine Drug Profiling Test
Two schizophrenic patients who had been taking medication for a long period presented with visual disturbance of 6-month duration. Slit-lamp examination revealed fine, discrete, and brownish deposits on the posterior cornea. In addition, bilateral star-shaped anterior subcapsular lens opacities, which were dense, dust-like granular deposits, were noted. Although we strongly suspected that the patient might have taken one of the drugs of the phenothiazine family, we were unable to obtain a history of medications other than haloperidol and risperidone, which were taken for 3 yr. We performed a drug profiling test using urine samples and detected methotrimeprazine. The patient underwent surgery for anterior subcapsular lens opacities. Visual acuity improved in both eyes, but the corneal deposits remained. We report an unusual case of methotrimeprazine-induced corneal deposits and cataract in a patient with psychosis, identified by using the urine drug profiling test
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