27 research outputs found
High resolution electron energy loss spectroscopy of GaAs and AlAs grown by molecular beam epitaxy
International audienc
Investigation of the AlAsGaAs interface by high resolution electron energy loss spectroscopy
International audienc
Trypanosoma brucei: a surface antigen mRNA is discontinuously transcribed from two distinct chromosomes.
The mRNAs for variant surface glycoproteins (VSGs) and many other proteins in Trypanosoma brucei start with the same sequence of 35 nucleotides, encoded by a separate mini-exon. There are approximately 200 mini-exon genes per trypanosome and these are highly clustered on large chromosomes. We have found two trypanosome variants that express a VSG gene located on a small, 225-kb chromosome. Each gene yields a mRNA containing the 35-nucleotide sequence even though the 225-kb chromosome does not contain a complete mini-exon gene. These results provide a strong support for the hypothesis that transcription of protein-coding genes in trypanosomes is discontinuous
Analysis of the chromosomal location of the VSG genes and their expression sites in two trypanosome clone derivations
info:eu-repo/semantics/publishe
Trypanosoma brucei: a surface antigen mRNA is discontinuously transcribed from two distinct chromosomes
The mRNAs for variant surface glycoproteins (VSGs) and many other proteins in Trypanosoma brucei start with the same sequence of 35 nucleotides, encoded by a separate mini-exon. There are approximately 200 mini-exon genes per trypanosome and these are highly clustered on large chromosomes. We have found two trypanosome variants that express a VSG gene located on a small, 225-kb chromosome. Each gene yields a mRNA containing the 35-nucleotide sequence even though the 225-kb chromosome does not contain a complete mini-exon gene. These results provide a strong support for the hypothesis that transcription of protein-coding genes in trypanosomes is discontinuous.Journal ArticleResearch Support, Non-U.S. Gov'tFLWINinfo:eu-repo/semantics/publishe