Non-Markovian Queueing System, Mx/G/1 with Server Breakdown and Repair Times

This paper deals with the steady state behavior of an MX/G/1 queue with breakdown. It assumed that customers arrive to the system in batches of variable size, but serve one by one. The main new assumption in this paper is that the repair process does not start immediately after a breakdown and there is a delay time waiting for repairs to start. We obtain steady state results in explicit and closed form in terms of the probability generating functions for the number of customers in the queue, the average waiting time in the queue

Biological Deterioration and their Chemical Conservation with Reference to Chandraditya Temple, Barsoor

Chandraditya temple is made up of sand stone which is sedimentary rock & its masonry is ashlars, but now is presently discoloured and deteriorated by growth and activity of living organism such as algae, fungus and lichen on stone surface had affected the structure badly; developing cracks as well as porosity of stones. Sand stone due to its porous nature absorbs more water in comparison to other stone & this water itself is main factor for the deterioration of stone structure.  The exterior portion of temple had become blackish due to deposition of dried moss, lichen and bacterial slime. Accumulation of dust, dirt was also a base for the growth of micro vegetation which secretes organic acid for causing the harmful to the structures. This paper deals with the biodeterioration and biodegradation of Chandraditya temple by fungi and their remedial measure applied on the monuments

Operator Duals of Vector Sequence Spaces

T. Balasubramaniam and A. Pandiarani [1] have defined the sequence spaces G(x). l (x), G(x) and have studied some topological property of their Köthe-Toeplitz duals in operator form. In this paper we define the new sequence spaces G0(x, p), Ge(x, p) and G¥(x,p) and have studied some topological property of their Köthe-Toeplitz duals in operator form

BIOANALYTICAL METHOD DEVELOPMENT AND VALIDATION OF NIRAPARIB IN PLASMA SAMPLES BY LC-MS/MS

In this manuscript, authors developed a simple, sensitive and specific liquid chromatography–tandem mass spectrometry (LC–MS/MS) method was used for quantification of Niraparib in plasma samples. Zorbax SB-C18, 4.6 x 75 mm, 3.5 μm, 80 Å column, 5mM ammonium acetate: methanol (30:70 v/v) mobile phase was used for Chromatographic separation of Niraparib. MRM positive mode was used to detect the Niraparib at 321.5195.4. Liquid-liquid extraction was employed in the extraction of analytes from human plasma. This method is validated over a linear concentration range of 10.0 – 10000.0 pg/mL with a correlation coefficient (r) of ≥ 0.9997. The developed method was validated and found to be table in plasma samples

Design and Development of Novel Matrix Converter Performance Enhancement Technique for Induction Motor Drive

Matrix converter is a direct AC-AC converter topology that directly converts energy from an AC source to an AC load without the need of a bulky and limited lifetime energy storage element. Due to the significant advantages offered by matrix converter, such as adjustable power factor, capability of regeneration and high quality sinusoidal input/output waveforms. Matrix converter has been one of the AC–AC topologies that hasreceived extensive research attention for being an alternative to replace traditional AC-DC-AC converters in the variable voltage and variable frequency AC drive applications. In the present paper an indirect space vector modulated matrix converter is proposed. The basic idea of an indirect modulation scheme is to separately apply SVM to the rectification and inversion stages, before combining their switching states to produce the final gating signals. The paper encompasses development of a laboratory prototype of 230V, 250VA three phase to three phase DSP controlled matrix converter fed induction motor drive. The observations and real time testings have been carried out to evaluate and improve the stability of system under various typical abnormal input voltage condition

Smokeless Tobacco dependence and cessation measures in India

India being the largest smokeless tobacco (SLT) producer and consumer in the South East Asia Region (SEAR) entitled with a range of products. SLT consumption is very common because it is associated with socio-economic and cultural perspectives in the India. After the implementation of the first treaty of the World Health Organization Framework Convention on Tobacco Control (WHO-FCTC), public health standards were reaffirmed and improvised through successful implementation of articles since 2007 as reported in the global progress factsheet. Many measures have been implemented for achieving the success of WHO-FCTC in India and to control the huge disease burden induced by tobacco use. The objective of the present study was to understand and explore the factors involved in the SLT demand reduction by revealing the dependence and cessation implementation in India in the context of strategies and policies. For this study, we searched for SLT dependence and SLT cessation literature survey in PubMed and obtained 102 literatures consisting of studies and reviews, which were further scrutinized by excluding the reviews, studies conducted abroad and studies conducted within the last 5 years (after 2015). No statistical significance was observed in comparison of National to International SLT dependence and an attempt to quit SLT following the tenure of a year. This is in-line with GATS-2 and international data. We have also discussed a diverse approach in the control of SLT at different levels-such as SLT users, healthcare professional, policy advocates supplier, labeling, legal policies, and educating at various platforms. Effective strategies for the cessation of SLT is mandatory with proper guidance for the manufacturer, users and sellers in controlling SLT products

High resolution ultrasonography of the tibial nerve in diabetic peripheral neuropathy

Aim of the study: High-resolution ultrasonography of the tibial nerve is a fast and non invasive tool for diagnosis of diabetic peripheral neuropathy. Our study was aimed at finding out the correlation of the cross sectional area and maximum thickness of nerve fascicles of the tibial nerve with the presence and severity of diabetic peripheral neuropathy. Material and methods: 75 patients with type 2 diabetes mellitus clinically diagnosed with diabetic peripheral neuropathy were analysed, and the severity of neuropathy was determined using the Toronto Clinical Neuropathy Score. 58 diabetic patients with no clinical suspicion of diabetic peripheral neuropathy and 75 healthy non-diabetic subjects were taken as controls. The cross sectional area and maximum thickness of nerve fascicles of the tibial nerves were calculated 3 cm cranial to the medial malleolus in both lower limbs. Results: The mean cross sectional area (22.63 +/– 2.66 mm2 ) and maximum thickness of nerve fascicles (0.70 mm) of the tibial nerves in patients with diabetic peripheral neuropathy compared with both control groups was significantly larger, and statistically significant correlation was found with the Toronto Clinical Neuropathy Score (p < 0.001). The diabetic patients with no signs of peripheral neuropathy had a larger mean cross sectional area (14.40 +/– 1.72 mm2 ) and maximum thickness of nerve fascicles of the tibial nerve (0.40 mm) than healthy non-diabetic subjects (12.42 +/– 1.01 mm2 and 0.30 mm respectively). Conclusion: The cross sectional area and maximum thickness of nerve fascicles of the tibial nerve is larger in diabetic patients with or without peripheral neuropathy than in healthy control subjects, and ultrasonography can be used as a good screening tool in these patients