1,410 research outputs found
Low Voltage Thin Layer Electrophoresis of Anions on Silica Gel-G And Titanium (IV) Tungstate Layers
The low voltage thin layer electrophoresis of anions has been studied on Silica Gel-G and titanium (iv) tungstate layers in in v arious complexing acid media such as Oxalic acid (O.A), Citric acid(C.A), Tartaric acid (T.A) and Succinic acid (S.A).The electrophoretic migration of anions also correlated with lyotropic number, N. The Spots are well defined in electrophoresis
Solubility Enhancement of Water Insoluble Drug for Ophthalmic Formulation
Product development of ophthalmic preparations has received considerable attention in the last few years. With the increasing emphasis on their sterility, some of the differences between them and parenteral preparations are becoming less evident. Both classes of preparations employ similar added substances and manufacturing procedures. The successful formulation of poorly water-soluble drugs is one of the major problems in pharmaceutical manufacturing. Poorly water-soluble drugs, such as indomethacin, may show low and erratic oral bioavailability due to poor dissolution of the drug in the fluids of the gastrointestinal tract. Indomethacin is a water insoluble drug, so problems of formulating an aqueous eye-drop are well known. Moreover, unstability of Indomethacin aqueous preparations is also a great challenge. In this research work, considering pharmacological importance of drug Indomethacin, we tried to overcome the problem of poor water solubility by making a salt of it and thus formulating an aqueous ophthalmic preparation.Keywords: ophthalmic preparation, indomethacin salt, aqueous eye drops, poor water soluble drugs
Charge multiplicity in relativistic heavy ion collisions: A statistical model approach
We use fireball geometry and a statistical model to calculate charged particle associated multiplicity in relativistic heavy ion reactions. General expressions for multiplicity distributions based upon this model are derived. The constraints of charge and baryon number conservation are shown to lead to modified Poisson distributions. The expressions developed are applicable to all nonstrange particles and composites. Comparison is made with existing data. NUCLEAR REACTIONS Relativistic heavy ion collisions; charge multiplicity; Fireball; statistical model
A Study on Incidence and Patterns of Acute Poisoning Cases in an Emergency Department of Western Region of Nepal
Introduction: Poisoning is a common cause of morbidity and mortality in the Nepal. The objective of our study is to evaluate the incidence and pattern of acute poisoning cases admitted to the Gandaki Medical Teaching Hospital.
Methods: This is cross-sectional observational study carried out among acute poisoning cases attending emergency department from January 2015 to December 2017.
Results: A total of 156 poisoning cases were treated of which female patients were 71% and the highest numbers (36.5%) of patients were in the age group 21 to 30 years. Organophosphates poisoning was the commonest poison diagnosed among 28.8%, followed by rodenticide poisoning found among 27.5%. Psychiatric illnesses were present among 94.8% of our patients. The most common diagnosis were Anxiety and depression 46.6% followed by family dispute among 30.4%. Above fifty percent of our patients attended our emergency department within 2 hours our ingestion of poisons.
Conclusion: Female and young people are at greater risk of acute poisoning. Pesticides were the most common agent. The reasons for the poisoning need to be carefully evaluated and proper support and advice must be given in poisoning cases
Spin and energy transfer in nanocrystals without transport of charge
We describe a mechanism of spin transfer between individual quantum dots that
does not require tunneling. Incident circularly-polarized photons create
inter-band excitons with non-zero electron spin in the first quantum dot. When
the quantum-dot pair is properly designed, this excitation can be transferred
to the neighboring dot via the Coulomb interaction with either {\it
conservation} or {\it flipping} of the electron spin. The second dot can
radiate circularly-polarized photons at lower energy. Selection rules for spin
transfer are determined by the resonant conditions and by the strong spin-orbit
interaction in the valence band of nanocrystals. Coulomb-induced energy and
spin transfer in pairs and chains of dots can become very efficient under
resonant conditions. The electron can preserve its spin orientation even in
randomly-oriented nanocrystals.Comment: 13 pages, 3 figure
The impact of the FREDDA dedispersion algorithm on H0 estimations with fast radio bursts
Fast radio bursts (FRBs) are transient radio signals of extragalactic origins that are subjected to propagation effects such as dispersion and scattering. It follows then that these signals hold information regarding the medium they have traversed and are hence useful as cosmological probes of the Universe. Recently, FRBs were used to make an independent measure of the Hubble constant H0, promising to resolve the Hubble tension given a sufficient number of detected FRBs. Such cosmological studies are dependent on FRB population statistics, cosmological parameters, and detection biases, and thus it is important to accurately characterize each of these. In this work, we empirically characterize the sensitivity of the Fast Real-time Engine for Dedispersing Amplitudes (FREDDA) which is the current detection system for the Australian Square Kilometre Array Pathfinder (ASKAP). We coherently redisperse high-time resolution data of 13 ASKAP-detected FRBs and inject them into FREDDA to determine the recovered signal-to-noise ratios as a function of dispersion measure. We find that for 11 of the 13 FRBs, these results are consistent with injecting idealized pulses. Approximating this sensitivity function with theoretical predictions results in a systematic error of 0.3 km s-1 Mpc-1 on H0 when it is the only free parameter. Allowing additional parameters to vary could increase this systematic by up to ⌠1 km s-1 Mpc-1. We estimate that this systematic will not be relevant until âŒ400 localized FRBs have been detected, but will likely be significant in resolving the Hubble tension
Inelastic production in polarized photon-hadron collisions
Presented here is a calculation of inelastic production in polarized
photon-hadron collisions under the framework of NRQCD factorization formalism.
We consider the photoproduction of \jpsi in the energy range relevant to
HERA. The Weizs\"acker-Williams approximation is adopted in the evaluation of
the cross sections for collisions. We found that this process can give
another independent test for the color-octet mechanism, and the different
features for the two color-octet processes may provide further informations on
the mechanism for inelastic \jpsi photoproduction. And the discrepancy on the
production asymmetry between various sets of polarized gluon distribution
functions is also found to be distinctive.Comment: 14pages, 6 PS figure
Delivering climate risk information to farmers at scale: the Intelligent agricultural Systems Advisory Tool (ISAT)
One of the strategies for helping smallholder farmers cope with climate variability and change is the provision of climate services that better decision making around the planning and management of agricultural systems. However, providing such services with location specific timely and actionable information to millions of farmers operating across diverse conditions requires innovative solutions. ICRISAT and its partners have developed and piloted one such system called âIntelligent agricultural Systems Advisory Tool â ISATâ capable of generating and disseminating data driven location specific advisories that assist farmers in anticipating and responding to the emerging conditions through the season. Using a decision tree approach, a structured and systematic approach to decision making was devised that considers the insights obtained from the analysis of historical climatic conditions, climate and weather forecasts and prevailing environmental conditions. Microsoft India developed a platform to access real time data from various âpublicâ sources, perform the data analytics, implement the decision tree and generate and disseminate messages to farmers and associated actors. The ISAT generated advisories are designed to support both pre-season planning and in-season management.
During the 2017 monsoon, ISAT was piloted with 417 farmers across four different locations. The messaging system worked extremely well in picking appropriate location specific message from the database and delivering the same to the mobiles of the registered farmers. Mid and end season surveys revealed that more than 80% of the farmers from all villages were satisfied with the frequency, relevance and understandability of the messages delivered. About 58% of the farmers rated the messages are reliable by being correct more than 75% of the times and helped them in managing their farms better by conducting farm operations timely with reduced risk. Compared to farmers in the control villages, groundnut yields of farmers in 5 treatment villages are higher by ~ 16% but this results varied between -7.7 to 56.2%. This study has demonstrated the opportunities available to harness the untapped power of digital technologies to provide actionable advisories timely to smallholder farmers using appropriate data analytics and information dissemination systems
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