1,678 research outputs found

    Analysis and Synthesis Prior Greedy Algorithms for Non-linear Sparse Recovery

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    In this work we address the problem of recovering sparse solutions to non linear inverse problems. We look at two variants of the basic problem, the synthesis prior problem when the solution is sparse and the analysis prior problem where the solution is cosparse in some linear basis. For the first problem, we propose non linear variants of the Orthogonal Matching Pursuit (OMP) and CoSamp algorithms; for the second problem we propose a non linear variant of the Greedy Analysis Pursuit (GAP) algorithm. We empirically test the success rates of our algorithms on exponential and logarithmic functions. We model speckle denoising as a non linear sparse recovery problem and apply our technique to solve it. Results show that our method outperforms state of the art methods in ultrasound speckle denoising

    Ormeloxifene versus combined oral contraceptive pills to control blood loss in cases of dysfunctional uterine bleeding

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    Background: Dysfunctional uterine bleeding is one of the most often encountered gynecologic problems causing anemia, reduced quality of life and unnecessary hysterectomies. A prospective study was conducted on women with DUB to study the effect of ormeloxifene versus combined oral contraceptive pills in controlling blood loss in them.Methods: 100 Women with DUB were enrolled randomly in three groups. After baseline assessment each patient in group A was treated with iron tablets, containing 100 mg elemental iron and folic acid 1.5 mg, for three months and were termed as control group. Group B patients were treated with ormeloxifene in dose of 60 mg twice a week for twelve weeks. Group C patients were treated with combined oral contraceptive pills for twenty- one days starting from third day of their LMP. The treatment was continued for three consecutive cycles. The efficacy of the studied drugs was analyzed by comparing the baseline and post treatment PBAC score, haemoglobin level and endometrial thickness, using appropriate statistical tests.Results: Ormeloxifene was more effective than only iron or combined oral contraceptive therapy in controlling menstrual blood loss (79.11% versus 58.57%). There was a reduction in endometrial thickness in group receiving ormeloxifene as well as in the group receiving combined oral contraceptive pills (p=0.486), however this was statistically not significant.Conclusions: Ormeloxifene was significantly better than combined OCP in reduction of menstrual blood flow in cases of DUB. It has better compliance and marked improvement in subjective symptoms as compared to OCP

    A comparison of hysterosalpingography and laparoscopy in the evaluation of tubal factors in female infertility

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    Background: WHO defines infertility as “failure to conceive after having regular, unprotected intercourse for one year. Factors responsible - male factors (20-30%), female factors (40-55%), combined male and female factors (10-40%) and unexplained infertility (10-20%). Amongst female factors, tubal factors are responsible for 25-30% of infertility. Hysterosalpingography and diagnostic laparoscopy with chromopertubation are widely used in the evaluation of tubal factors of infertility. The aim of this study was to compare findings of HSG and diagnostic laparoscopy with chromopertubation for tubal patency in infertile women.Methods: An observational study, done on a total of 125 females suffering from primary and secondary infertility who underwent HSG and then 97 patients who gave consent, underwent diagnostic laparoscopy with chromopertubation. The data was entered in MS excel spreadsheet and analysis was done using statistical package for social sciences (SPSS) version 21.0.Results: Primary infertility cases were more than secondary infertility cases. Mean age of patients was found to be 28.92±5.33 years. Most common tubal abnormality found on hysterosalpingography and chromopertubation was bilateral tubal block. Inter rater kappa agreement used and significant agreement found between hysterosalpingography and chromopertubation with kappa value of 0.612.Conclusions: From this study authors conclude that HSG and laparoscopy with chromopertubation are complimentary to each other. Laparoscopy helps in identification of tubal and non-tubal factors like intra-abdominal and pelvic adhesions, endometriosis etc. and simultaneously they can be treated while HSG helps in evaluation of tubal factors as well as of intra-uterine factors like synechiae, polyps etc

    QUANTUM PHENOMENA IN ZERO DIMENSIONS: QUANTUM DOTS

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    Quantum phenomena in zero dimensions: quantum dots because of many interesting and important applications currently in use by this nanotechnology. The use fulness and application of quantum dots technologically continues to expand and research is striving to bring their benefits to more and more technologically applied fields. SMALLER...smaller...smaller-In the semiconductor industry, this mantra translates to faster...... faster.....faster. The question is, how small can we go? At Lawrence Livermore National Laboratory, the answer may be: as small as quantum dots. Quantum dot has some attractive advantages: long-term photostability, higher fluorescent outcome, narrower fluorescence emission, sensitivity to the electric and magnetic f

    OPTIMIZATION AND CHARACTERIZATION OF ION ACTIVATED OCULAR IN-SITU GEL FORMULATION FOR BACTERIAL CONJUNCTIVITIS

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    Objective: The present research work aims at describing the formulation, optimization and evaluation of ion activated ocular in-situ gel of gatifloxacin for treatment of bacterial conjunctivitis so as to overcome patient inconvenience, precorneal drug elimination, variation in efficacy, vision blurring and frequent instillation associated with conventional eye drops and ointments. Methods: In-situ gel was prepared using gellan gum as an ion activated phase transition polymer and HPMC K100M as release retardant. Gatifloxacin was characterized by spectrophotometry. Crystalline state of the drug was determined using X Ray Diffraction study. The developed formulation exhibited instantaneous gel formation in simulated lacrimal fluid (pH 7.4), which was further evaluated for its rheology, irritancy parameters, in vitro release, trans-corneal permeation and antimicrobial activity. Results: Gatifloxacin exhibited λmax 286 nm obeying Beer Lambert’s law and pH-dependent solubility at a pH range of 2 to 4. 0.6% gellan gum and 0.4% HPMC K100M were optimized in the formulation which exhibited a viscosity of 55 cps in sol form and 325 cps in gel form with pseudoplastic behavior and prolonged in vitro release. Permeation of formulation was 75.8% in 7 h with log P of drug 0.59. Developed isotonic and non-irritant formulation had a lower apparent permeability coefficient of 8.15 x 10-5 cm/sec as compared to marketed formulation. Conclusion: A Formulation can be viewed as an efficacious medicine by virtue of its higher zone of inhibition, ability to enhance precorneal residence time and consequently ocular bioavailability with lesser frequency of administration attributed to slow and prolonged diffusion of the drug from the polymeric solutions

    Imbursement Array in Dental Practice Management A Review

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    Dentistry is a dignified healthcare profession but due to transient transformation in dental practice, dentistry has reached to its peak level. The main barrier to cater the dental services throughout all area including rural and urban is financial which has to be removed. Thus, to maintain the glory of the profession and to reach the people at their doorsteps, proper practice management of finance in terms of payment is very important. We present a review on imbursement array in dental practice management which was obtained from the literature search of published articles, online manuals and books

    Immense Potential of Ayurveda in Improving Dental Health: A Holistic Approach

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    There has been a change in thinking of the people across the world with a growing tendency towards “GO NATURAL” especially in the field of health sciences. Ayurveda is the ancient Indian system of health-care and longevity and should be considered as an alternative by integrating it with the modern dentistry. The present review aims to discuss various Ayurvedic plants and their significance in dentistry. Along with the PUBMED, MEDLINE, Medknow indexed journals, peer-reviewed and non-indexed journals were also reviewed using aloe vera, turmeric, honey, licorice, triphala and oral health as the keywords. The incorporation of Ayurveda into modern oral health-care practices will make dentistry much safer, affordable and more accessible for the lower socio-economic groups in society

    Multimapper: Data Density Sensitive Topological Visualization

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    Mapper is an algorithm that summarizes the topological information contained in a dataset and provides an insightful visualization. It takes as input a point cloud which is possibly high-dimensional, a filter function on it and an open cover on the range of the function. It returns the nerve simplicial complex of the pullback of the cover. Mapper can be considered a discrete approximation of the topological construct called Reeb space, as analysed in the 11-dimensional case by [Carriere et al.,2018]. Despite its success in obtaining insights in various fields such as in [Kamruzzaman et al., 2016], Mapper is an ad hoc technique requiring lots of parameter tuning. There is also no measure to quantify goodness of the resulting visualization, which often deviates from the Reeb space in practice. In this paper, we introduce a new cover selection scheme for data that reduces the obscuration of topological information at both the computation and visualisation steps. To achieve this, we replace global scale selection of cover with a scale selection scheme sensitive to local density of data points. We also propose a method to detect some deviations in Mapper from Reeb space via computation of persistence features on the Mapper graph.Comment: Accepted at ICDM

    A REVIEW ON PHYSIOLOGY OF MANASA (PSYCHE) IN AYURVEDA

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    Mental health is given equal importance at various places in Ayurvedic texts. Ayurveda emphasizes that Sharira (body) and Sattva (mind) both interact with one another in all spheres of life. The Ayurvedic approach towards health and disease is entirely psychosomatic in its nature. Ayurveda greatly emphasizes on the phenomena of mind than that of the body. This can be expounded by the definition of health, the causes of disease, the approach to the examination of the patient, the concept of the psychosomatic constitution i.e. Prakruti, the regimen of mental and physical hygiene. Therefore it is imperative to understand about the physiology, functions and enactments of Mind i.e. Manasa in Ayurveda. This review article is based upon the fundamentals describing Manasa and its functions and physiology. It is very important to understand each and every aspect of Manas for an Ayurvedic scholar or physician for complete knowledge of human body and behavior
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