Key Problems to be solved in Supply Chain Collaboration Management

Supply chain members of independent enterprises are different from each other in strategies. Conflict in benefits is inevitable. The supply chain management system (SCMS) based on information system usually emphasizes on the function of the information technology. To achieve collaboration management, four main problems must be solved:1)Belief among supply chain members,2)Motivations of supply chain members, 3)Allocation of interests among supply chain members, 4)Integration of supply chain information system.This paper intends to analyze these key problems, and put forward some resolutions

NRAV, a Long Noncoding RNA, Modulates Antiviral Responses through Suppression of Interferon-Stimulated Gene Transcription

SummaryLong noncoding RNAs (lncRNAs) modulate various biological processes, but their role in host antiviral responses is largely unknown. Here we identify a lncRNA as a key regulator of antiviral innate immunity. Following from the observation that a lncRNA that we call negative regulator of antiviral response (NRAV) was dramatically downregulated during infection with several viruses, we ectopically expressed NRAV in human cells or transgenic mice and found that it significantly promotes influenza A virus (IAV) replication and virulence. Conversely, silencing NRAV suppressed IAV replication and virus production, suggesting that reduction of NRAV is part of the host antiviral innate immune response to virus infection. NRAV negatively regulates the initial transcription of multiple critical interferon-stimulated genes (ISGs), including IFITM3 and MxA, by affecting histone modification of these genes. Our results provide evidence for a lncRNA in modulating the antiviral interferon response

Comparative transcriptome analysis of genes involved in paradormant bud release response in ‘Summer Black’ grape

Grapevines possess a hierarchy of buds, and the fruitful winter bud forms the foundation of the two-crop-a-year cultivation system, yielding biannual harvests. Throughout its developmental stages, the winter bud sequentially undergoes paradormancy, endodormancy, and ecodormancy to ensure survival in challenging environmental conditions. Releasing the endodormancy of winter bud results in the first crop yield, while breaking the paradormancy of winter bud allows for the second crop harvest. Hydrogen cyanamide serves as an agent to break endodormancy, which counteracting the inhibitory effects of ABA, while H2O2 and ethylene function as signaling molecules in the process of endodormancy release. In the context of breaking paradormancy, common agronomic practices include short pruning and hydrogen cyanamide treatment. However, the mechanism of hydrogen cyanamide contributes to this process remains unknown. This study confirms that hydrogen cyanamide treatment significantly improved both the speed and uniformity of bud sprouting, while short pruning proved to be an effective method for releasing paradormancy until August. This observation highlights the role of apical dominance as a primary inhibitory factor in suppressing the sprouting of paradormant winter bud. Comparative transcriptome analysis revealed that the sixth node winter bud convert to apical tissue following short pruning and established a polar auxin transport canal through the upregulated expression of VvPIN3 and VvTIR1. Moreover, short pruning induced the generation of reactive oxygen species, and wounding, ethylene, and H2O2 collectively acted as stimulating signals and amplified effects through the MAPK cascade. In contrast, hydrogen cyanamide treatment directly disrupted mitochondrial function, resulting in ROS production and an extended efficacy of the growth hormone signaling pathway induction

3D-IDS: Doubly Disentangled Dynamic Intrusion Detection

Network-based intrusion detection system (NIDS) monitors network traffic for malicious activities, forming the frontline defense against increasing attacks over information infrastructures. Although promising, our quantitative analysis shows that existing methods perform inconsistently in declaring various unknown attacks (e.g., 9% and 35% F1 respectively for two distinct unknown threats for an SVM-based method) or detecting diverse known attacks (e.g., 31% F1 for the Backdoor and 93% F1 for DDoS by a GCN-based state-of-the-art method), and reveals that the underlying cause is entangled distributions of flow features. This motivates us to propose 3D-IDS, a novel method that aims to tackle the above issues through two-step feature disentanglements and a dynamic graph diffusion scheme. Specifically, we first disentangle traffic features by a non-parameterized optimization based on mutual information, automatically differentiating tens and hundreds of complex features of various attacks. Such differentiated features will be fed into a memory model to generate representations, which are further disentangled to highlight the attack-specific features. Finally, we use a novel graph diffusion method that dynamically fuses the network topology for spatial-temporal aggregation in evolving data streams. By doing so, we can effectively identify various attacks in encrypted traffics, including unknown threats and known ones that are not easily detected. Experiments show the superiority of our 3D-IDS. We also demonstrate that our two-step feature disentanglements benefit the explainability of NIDS.Comment: Accepted and appeared in the proceedings of the KDD 2023 Research Trac

Investigation of the chemical residuals on the fused silica during chemical mechanical polishing

Chemical residuals on fused silica after chemical mechanical polishing with silica and ceria have been analyzed. The surface of fused silica terminates with silanol after being polished with silica abrasives but ends up with Ce‐O−Si in a ceria‐based slurry under the CMP environment. The silanol firstly synthesizes on a fused silica surface polished with ceria, but then further reacts with hydroxyl cerium groups scattering in the slurry forming Ce‐O−Si. It also reveals that polishing fused silica with silica abrasives is an alternative way giving an ultra smooth surface

Luxury uptake of aerosol iron by Trichodesmium in the western tropical North Atlantic

Dust transported from North Africa carries micronutrient iron (Fe) to the western tropical North Atlantic (WTNA) which may significantly influence the metabolism of the N2-fixing cyanobacteria, Trichodesmium. For the first time, we conducted shipboard incubation experiments using freshly collected aerosol, seawater, and Trichodesmium colonies. Trichodesmium assimilated significant amount of aerosol Fe up to 14 times higher than the control. The uptake amount increased proportionally to the P: Fe ratio that Trichodesmium initially contained and to the aerosol Fe added and leached to the incubation solution. Trichodesmium assimilated more aerosol Fe than needed for its maximum growth (0.14 d-1) demonstrating a high capacity of luxury uptake of Fe from the dust. Copyright 2011 by the American Geophysical Union.This work is sponsored by China Shanghai Pujiang Program (09PJ1401200), China National Natural Science Foundation (41005075), and Program for New Century Excellent Talents in University (NCET-09-0308).Peer Reviewe

An Optimized Implementation of Activation Instruction Based on RISC-V

Activation is an important component of the neural network, and the standard instructions of RISC-V are difficult to use to effectively handle the activation of the array. In this paper, we propose an optimized implementation of activation instruction based on RISC-V. Based on the opensource RISC-V processor Hummingbird E203, we designed a special instruction for the implementation of activation functions. A single instruction is chosen to implement the entire activation operation, including data loading, data arithmetic and data write-back. At the hardware level, we designed a method of alternate reading and writing that only needs a small hardware storage unit to meet the requirements of the activation operation for long arrays without affecting the activation efficiency. In addition, we added the length of the array as a new parameter to instruct our designed hardware to adapt to any length of arrays. Finally, the scheduling method of some instructions in the activation process was optimized in accordance with the law of instructions, which improves the execution efficiency of instructions. Considering an activation process with an array length of 15, our design demonstrates a 4.89-fold increase in speed compared to RISC-V standard instructions while consuming only 7.78% of the energy

Hysteresis effect on austenite-martensite interface in Ni-Mn-Ga single crystal

The experiments on Ni-Mn-Ga single crystal shape memory alloy under a heating-cooling cycle demonstrate that the automatically generated twin laminate structure of the compatible austenite-martensite interface in the forward martensitic phase transition is significantly different from that in the reverse phase transition, even though the temperature hysteresis is small (As - Ms around 4 ◦C). Moreover, after the cooling-induced austenite → martensite transition, the remaining twin laminate is so fine (layer width around 1 μm) that the neighbouring twin boundaries merge with each other and disappear, making the fine twin laminate evolve into a single martensite variant (i.e., spontaneous detwinning). These observations provide insights into the relation betweenthe hysteresis (phase-transition driving forces), austenite-martensite interface, and the basic material parameters such as twin boundary energy and softening modulus during the phase transition