Electromagnetic radiation of baryons containing two heavy quarks

The two heavy quarks in a baryon which contains two heavy quarks and a light one, can constitute a scalar or axial vector diquark. We study electromagnetic radiations of such baryons, (i) \Xi_{(bc)_1} -> \Xi_{(bc)_0}+\gamma, (ii) \Xi_{(bc)_1}^* -> \Xi_{(bc)_0}+\gamma, (iii) \Xi_{(bc)_0}^{**}(1/2, l=1) -> \Xi_{(bc)_0}+\gamma, (iv) \Xi_{(bc)_0}^{**}(3/2, l=1) -> \Xi_{(bc)_0}+\gamma and (v) \Xi_{(bc)_0}^{**}(3/2, l=2) -> \Xi_{(bc)_0}+\gamma, where \Xi_{(bc)_{0(1)}}, \Xi^*_{(bc)_1} are S-wave bound states of a heavy scalar or axial vector diquark and a light quark, and \Xi_{(bc)_0}^{**}(l is bigger than 1) are P- or D-wave bound states of a heavy scalar diquark and a light quark. Analysis indicates that these processes can be attributed into two categories and the physical mechanisms which are responsible for them are completely distinct. Measurements can provide a good judgment for the diquark structure and better understanding of the physical picture.Comment: 15 pages, Late

Nrf2 Deficiency Augments the Activity of Hepatic Progenitor Cells during Cholestasis

poster abstractTranscription factor nuclear factor erythroid 2-related factor 2 (Nrf2) is a central regulator of cellular defense against oxidative stress and inflammation and is also involved in regulating liver regeneration. The aim of the study is to evaluate whether Nrf2 mediates hepatic repair response during cholestasis. Wild-type and Nrf2-null mice were subjected to bile duct ligation or sham operation. Various assessments were performed at 5, 10, 15, 25, and 40 days following surgery. Significant genotype-dependent differences in liver injury, cell proliferation, and collagen deposition were not seen over the time course of the study, in line with several reports. However, Nrf2-null mice exhibited a more prominent network of septual tissue containing laminin and α-fetal protein expressing cells at 15 days after injury, suggesting a stronger repair response, than their wild-type litter mates. In the livers of both genotypes of mice, cytokeratin 19 (CK19), a marker of bipotent liver epithelial progenitors and immature billiary epithelial cells, were expressed in the epithelial cells of newly formed bile ducts and a population of hepatocytic-appearing cells in parenchyma. Notably, Nrf2-null mice showed higher hepatic protein expression of CK19 at 5 days following BDL, indicating earlier onset of the activation of CK19+ progenitor cells, than wild-types. CD133, a marker of liver progenitors, were found to be expressed by newly generated bile duct epithelial cells and a population of hepatocytic-appearing parenchymal cells in the livers of the two genotypes of mice. Hepatic CD133 protein expression was gradually elevated, paralleling continuous increase in the number of CD133+ hepatocytic-appearing cells, as the cholestasis progressed. Remarkably, the lack of Nrf2 led to markedly higher magnitudes of the increases in hepatic CD133 protein level and in the number of CD133+ hepatocytic-appearing cells. Collectively, our data demonstrate that Nrf2 deficiency evokes higher activity of liver progenitor cells and thus stronger liver repair response. The findings indicate that Nrf2 is an important regulator of the activity of hepatic progenitor/stem cells during chronic liver injury

On converse bounds for classical communication over quantum channels

We explore several new converse bounds for classical communication over quantum channels in both the one-shot and asymptotic regimes. First, we show that the Matthews-Wehner meta-converse bound for entanglement-assisted classical communication can be achieved by activated, no-signalling assisted codes, suitably generalizing a result for classical channels. Second, we derive a new efficiently computable meta-converse on the amount of classical information unassisted codes can transmit over a single use of a quantum channel. As applications, we provide a finite resource analysis of classical communication over quantum erasure channels, including the second-order and moderate deviation asymptotics. Third, we explore the asymptotic analogue of our new meta-converse, the $\Upsilon$-information of the channel. We show that its regularization is an upper bound on the classical capacity, which is generally tighter than the entanglement-assisted capacity and other known efficiently computable strong converse bounds. For covariant channels we show that the $\Upsilon$-information is a strong converse bound.Comment: v3: published version; v2: 18 pages, presentation and results improve

Power of linkage analysis using traits generated from simulated longitudinal data of the Framingham Heart Study

The Framingham Heart Study is a very successful longitudinal research for cardiovascular diseases. The completion of a 10-cM genome scan in Framingham families provided an opportunity to evaluate linkage using longitudinal data. Several descriptive traits based on simulated longitudinal data from the Genetic Analysis Workshop 13 (GAW13) were generated, and linkage analyses were performed for these traits. We compared the power of detecting linkage for baseline and slope genes in the simulated data of GAW13 using these traits. We found that using longitudinal traits based on multiple follow-ups may not be more powerful than using cross-sectional traits for genetic linkage analysis

Genome-wide linkage analysis using cross-sectional and longitudinal traits for body mass index in a subsample of the Framingham Heart Study

To evaluate linkage evidence for body mass index (BMI) using both cross-sectional and longitudinal data, we performed genome-wide multipoint linkage analyses on subjects who had complete data at four selected time points (initial, 8(th), 12(th), and 16(th )year following the initial visit) from the Framingham Heart Study. The cross-sectional measures included BMI at each of the four selected time points and the longitudinal measure was the within-subject mean of BMI at the above four time points. Using the variance components method, we consistently observed the maximum LOD score out of the genome scan using BMI at each time point and the mean of BMI between 049xd2 and GATA71H05 on chromosome 16. The highest LOD score (3.0) was at time point 1, while the lowest (1.9) was at time point 4. We also observed other suggestive linkages on chromosome 6, 10, and 18 at time point 1 only. The longitudinal measure we studied (mean of BMI) did not provide greater power to identify a positive linkage than some of the cross-sectional measures (e.g., time point 1). The changing of linkage evidence over time provided some insights on the variation of genetic effect on BMI with aging. There may be a QTL on chromosome 16 that contributes to BMI and this locus, and maybe others, is more likely to affect BMI during early adulthood

Observation of giant nonreciprocal charge transport from quantum Hall edge states of single surface in topological insulator

Symmetry breaking in quantum materials is of great importance and leads to novel nonreciprocal charge transport. The topological insulator system provides a unique platform to study nonreciprocal charge transport due to the exotic surface state. But it is typically small in magnitude because the contributions from the top and bottom surface of topological insulator are usually opposite. Here, we report the observation of giant nonreciprocal charge transport mediated by the quantum Hall state in intrinsic topological insulator Sn-Bi1.1Sb0.9Te2S devices, which is attributed to the coexistence of quantum Hall states and Dirac surface states. A giant nonreciprocal coefficient of up to 2.26*10^5 A^-1 is found, because only a single surface of topological insulator contributes to the nonreciprocal charge transport. Our work not only reveals the intrinsic properties of nonreciprocal charge transport in topological insulators, but also paves the way for future electronic devices

Spin waves in the block checkerboard antiferromagnetic phase

Motivated by the discovery of new family 122 iron-based superconductors, we present the theoretical results on the ground state phase diagram, spin wave and dynamic structure factor of the extended $J_{1}-J_{2}$ Heisenberg model. In the reasonable physical parameter region of $K_{2}Fe_{4}Se_{5}$, we fi{}nd the block checkerboard antiferromagnetic order phase is stable. There are two acoustic branches and six optical branches spin wave in the block checkerboard antiferromagnetic phase, which has analytic expression in the high symmetry points. To compare the further neutron scattering experiments, we discuss the saddlepoint structure in the magnetic excitation spectrum and calculate the predicted inelastic neutron scattering pattern based on linear spin wave theory

Identification of a novel reactive oxygen species (ROS)-related genes model combined with RT-qPCR experiments for prognosis and immunotherapy in gastric cancer

Reactive oxygen species play a crucial role in the prognosis and tumor microenvironment (TME) of malignant tumors. An ROS-related signature was constructed in gastric cancer (GC) samples from TCGA database. ROS-related genes were obtained from the Molecular Signatures Database. Consensus clustering was used to establish distinct ROS-related subtypes related to different survival and immune cell infiltration patterns. Sequentially, prognostic genes were identified in the ROS-related subtypes, which were used to identify a stable ROS-related signature that predicted the prognosis of GC. Correlation analysis revealed the significance of immune cell iniltration, immunotherapy, and drug sensitivity in gastric cancers with different risks. The putative molecular mechanisms of the different gastric cancer risks were revealed by functional enrichment analysis. A robust nomogram was established to predict the outcome of each gastric cancer. Finally, we verified the expression of the genes involved in the model using RT-qPCR. In conclusion, the ROS-related signature in this study is a novel and stable biomarker associated with TME and immunotherapy responses