Primary Large Cell Neuroendocrine Carcinoma of the Breast: Radiologic and Pathologic Findings

Some breast neoplasms are classified as primary neuroendocrine carcinomas because they are positive for neuroendocrine markers. Although neuroendocrine carcinomas can originate from various organs of the body, primary neuroendocrine carcinomas of the breast are extremely rare. The diagnosis of primary neuroendocrine carcinoma of the breast can only be made if nonmammary sites are confidently excluded or if an in situ component can be found. Here we report a primary large-cell neuroendocrine carcinoma (LCNL) involving the left breast. Breast ultrasonography revealed a lobulated, heterogeneous, low-echoic mass in the left breast, and the lesion ap-peared as a well-defined, highly-enhancing mass on a chest computed tomography scan. Ultrasound-guided core needle biopsy was performed on the mass, and primary LCNC was confirmed by histopathologic examination

Imaging Findings of Invasive Micropapillary Carcinoma of the Breast

Purpose: The purpose of this study is to evaluate imaging and histopathologic findings including the immunohistochemical characteristics of invasive micropapillary carcinoma (IMPC) of the breast. Methods: Twenty-nine patients diagnosed with IMPC were included in the present study. Mammographic, sonographic, and magnetic resonance imaging (MRI) findings were analyzed retrospectively according to the American College of Radiology Breast Imaging Reporting and Data System lexicon. 18 F-fluorodeoxyglucose positron emission tomography-computed tomography (PET-CT) findings were also evaluated. Microscopic slides of surgical specimens were reviewed in consensus by two pathologists with a specialty in breast pathology. Results: Most IMPCs presented as a high density irregular mass with a non-circumscribed margin associated with microcalcifications on mammography, as an irregular hypoechoic mass with a spiculated margi

Endoscopic sinus surgery in the isolated paranasal sinus aspergilloma [La chirurgie endoscopique pour l'aspergillome d'un sinus paranasal]

PubMed ID: 10769567Fungal infections of the paranasal sinuses are in four clinical forms. Beside the acute fulminating form, chronic invasive form, allergic fungal sinusitis and fungus ball. Fungus ball is mostly encountered in only one paranasal sinus of an otherwise healthy person. Ten fungus balls of the paranasal sinuses are presented with their management and results

Inflammatory breast carcinoma: Mammographic, ultrasonographic, clinical, and pathologic findings in 142 cases

WOS: 000175757300033PubMed ID: 12034956PURPOSE: To determine and quantitate radiologic characteristics of inflammatory breast carcinoma and to report clinical and pathologic findings. MATERIALS AND METHODS: A retrospective review of records of 2,733 women who received a diagnosis of breast carcinoma between January 1988 and May 2000 revealed 142 histologically proved inflammatory carcinomas. Analysis included history; findings at physical examination, mammography, and ultrasonography (US); and histologic type of inflammatory carcinoma. RESULTS: At physical examination, skin changes (n = 115, 81%) were the most common findings. A palpable mass was noted in 62% (n = 88), with axillary lymph node involvement in 68% (n = 96) of the carcinomas. Mammography revealed findings in carcinomas: skin thickening, 84% (n = 119); diffusely increased density, 37% (n = 53); trabecular thickening, 81% (n = 115); mass, 16% (n = 23); asymmetric focal density, 61% (n = 87); microcalcifications, 56% (n = 80); nipple retraction, 43% (n = 61); and axillary lymphadenopathy, 24% (n = 34). US showed changes in carcinomas: skin thickening, 96% (n = 136); parenchymal echogenicity changes, 73% (n = 104); dilated lymphatic channels, 68% (n = 96); solid mass, 80% (n = 114); pectoral muscle invasion, 10% (n = 14); focal areas of parenchymal acoustic shadowing, 37% (n = 52); and axillary lymphadenopathy, 73% (n = 104). CONCLUSION: Presence of isolated inflammatory signs is sufficient to suggest inflammatory breast carcinoma clinically. Inflammatory breast carcinoma has a mammographic pattern of inflammatory changes, such as skin thickening and stromal coarsening and/or diffusely increased breast density with or without an associated mass and/or malignant-type microcalcifications. US is helpful not only in depiction of masses masked by the edema pattern but also in demonstration of skin and pectoral muscle invasion and axillary involvement. (C) RSNA, 2002

Mental substitution investigation test

[No abstract available

Breast metastasis from low-grade endometrial stromal sarcoma after a 17-year period

WOS: 000179925300026PubMed ID: 12439586Metastases to the breast are rare with an incidence of 0.5-3% of patients with extramammary carcinomas. We report a unique case of an endometrial stromal sarcoma metastasizing to the breast after a 17-year-period. Mammographic and ultrasonographic findings with histopathological correlation are described

Male breast disease: clinical, mammographic, and ultrasonographic features

WOS: 000178531200008PubMed ID: 12204407Purpose: To describe and quantitate the radiological (mammographic and ultrasonographic) characteristics of male breast disease and to report the clinical and pathological findings. Materials and methods: Two-hundred-thirty-six male patients with different male breast diseases, diagnosed at our institution between January 1990 and July 2001, were retrospectively evaluated. The history, physical examination, mammographic and ultrasonographic findings were analyzed. Results: The spectrum of the disease in 236 male patients were gynecomastia (n = 206), primary breast carcinoma (n = 14), fat necrosis (n = 5), lipoma (n = 3), subareolar abscess (n = 2), epidermal inclusion cyst (n = 1), sebaceous cyst (n = 1), hematoma (n = 1), myeloma (n = 1), and metastatic carcinoma (n = 2). The distribution of patterns of gynecomastia were; 34% (n = 71) nodular, 35% (n = 73) dendritic and 34% (n = 62) diffuse glandular. Gynecomastia was unilateral in 55% (n = 113) and bilateral in 45% (n = 93) of the patients. Male breast cancer presented as a mass without microcalcifications in 86% (n = 12) and with microcalcifications in 7% (n = 1) of patients. The mass was obscured by gynecomastia, partially in two, totally in one patient. The location of the mass was retroareolar in 46% (n = 6) and eccentric to the nipple in 54% (n = 7) of patients. On ultrasonography (US), the contours were well-circumscribed in 20% (n = 3) and irregular in 80% (n = 12) of the masses. Conclusion: Male breast has a wide spectrum of diseases, some of which have characteristic radiological appearances that can be correlated with their pathologic diagnosis. In the evaluation of the male breast, mammography and US are essential and should be performed along with physical examination. (C) 2002 Elsevier Science Ireland Ltd. All rights reserved