Schistosoma mansoni Infection in Finchaa Sugar Estate: Public health Problem Assessment based on Clinical Records and Parasitological Surveys, Western Ethiopia

The survey of Schistosoma mansoni (S. mansoni) in Finchaa Sugar Estate, Western Ethiopia, was conducted to investigate the prevalence and health problems of schistosomiasis with some of the risk factors. The examination was undertaken based on the analysis of retrospective clinical data from the health center and a cross-sectional parasitological examinations using Kato-thick smear slides in April-June 2012/2013. Over the period 2008 to 2013 average prevalence among suspected patients at the health centre was 30.9%. Examination of double kato-thick smear slides from a random sample of 602 individuals from most schistosomiasis affected camp 7 revealed the prevalence of 37.5%. S. mansoni infection is become a year-round public health problem in Finchaa, Sugar Estate possibly due to permanent streams, water bodies and water contact behaviors and also reduced effectiveness of current control measures. Among the 7th camps, village A (camp 7) is the most schistosomiasis affected area (37.5%) followed by Kuyisa (25%). This is attributed to the presence of permanent stream (Fekerie stream) near camp 7. The present finding shows that the prevalence and intensity of schistosomiasis in the more affected camp 7 of Finchaa Sugar Estate was significantly higher among males than in females and its prevalence and intensity was found to be higher among study population within the age group of 11-20 years old. This study indicates that schistosomiasis is a major health problem in Finchaa Sugar Estate with moderate prevalence. The study results will provide an additional clinical and parasitological data on the current status of S. mansoni in Finchaa Sugar Estate and could serve as a guide in designing, developing and implementing intervention strategies to mitigate morbidity due to S. mansoni especially in highly risk groups under the Ethiopian health service system.Keywords: Egg per gram; Finchaa Sugar Estate; Kato-katz; Schistosomiasis; S. mansoni; Public healt

The effects of chest wall loading on perceptions of fatigue, exercise performance, pulmonary function, and muscle perfusion.

BACKGROUND: Load carriage (LC), which directly affects the chest wall and locomotor muscles, has been suggested to alter the ventilatory and circulatory responses to exercise, leading to increased respiratory muscle work and fatigue. However, studies exploring the impact of LC on locomotion increased internal work, complicating their interpretation. To overcome this issue, we sought to determine the effect of chest wall loading with restriction (CWL + R) on cycling performance, cardiopulmonary responses, microvascular responsiveness, and perceptions of fatigue. METHODS: In a randomized crossover design, 23 young healthy males (22 \ub1 4 years) completed a 5 km cycling time trial (TT) in loaded (CWL + R; tightened vest with 10% body weight) and unloaded conditions. After baseline pulmonary function testing (PFT; forced expiratory volume in 1 s, FEV1; forced vital capacity, FVC), cardiopulmonary indices (HR, heart rate; O2 uptake, VO2; ventilation, VE; tidal volume, VT; and breathing frequency, Bf), rating of perceived exertion (RPE), lactate (BLa), and microvascular responses (oxy-, deoxy-, total hemoglobin; and tissue saturation; StO2) of the vastus lateralis using near infrared spectroscopy were collected during the TT; and PFT was repeated post-exercise. RESULTS: Pre-exercise, CWL + R reduced (p < 0.05) FVC (5.6 \ub1 0.8 versus 5.5 \ub1 0.7 L), FEV1 (4.8 \ub1 0.7 versus 4.7 \ub1 0.6 L), and FEV1/FVC (0.9 \ub1 0.1 versus 0.8 \ub1 0.1). CWL + R modified power output (PO) over time (interaction, p = 0.02), although the 5 km time (461 \ub1 24 versus 470 \ub1 27 seconds), VT (3.0 \ub1 0.3 versus 2.8 \ub1 0.8 L), Bf, VE, HR, VO2, microvascular and perceptual (visual analog scale, or VAS, and RPE) responses were unchanged (p > 0.05). CWL + R increased (p < 0.05) the average BLa (7.6 \ub1 2.6 versus 8.6 \ub1 3 mmol/L). CONCLUSIONS: Modest CWL + R negatively affects pre-exercise pulmonary function, modifies cycling power output over time, and increases lactate production during a 5 km cycling trial, although the cardiorespiratory, microvascular, and perceptual responses were unaffected

COMPASS: a 2.6m telescope for CMBR polarization studies

COMPASS (COsmic Microwave Polarization at Small Scale) is an experiment devoted to measuring the polarization of the CMBR. Its design and characteristics are presented

Temperature inversion symmetry in the Casimir effect with an antiperiodic boundary condition

We present explicitly another example of a temperature inversion symmetry in the Casimir effect for a nonsymmetric boundary condition. We also give an interpretation for our result.Comment: 4 page

Breaking the Redshift Deadlock - I: Constraining the star formation history of galaxies with sub-millimetre photometric redshifts

Future extragalactic sub-millimetre and millimetre surveys have the potential to provide a sensitive census of the level of obscured star formation in galaxies at all redshifts. While in general there is good agreement between the source counts from existing SCUBA (850um) and MAMBO (1.25mm) surveys of different depths and areas, it remains difficult to determine the redshift distribution and bolometric luminosities of the sub-millimetre and millimetre galaxy population. This is principally due to the ambiguity in identifying an individual sub-millimetre source with its optical, IR or radio counterpart which, in turn, prevents a confident measurement of the spectroscopic redshift. Additionally, the lack of data measuring the rest-frame FIR spectral peak of the sub-millimetre galaxies gives rise to poor constraints on their rest-frame FIR luminosities and star formation rates. In this paper we describe Monte-Carlo simulations of ground-based, balloon-borne and satellite sub-millimetre surveys that demonstrate how the rest-frame FIR-sub-millimetre spectral energy distributions (250-850um) can be used to derive photometric redshifts with an r.m.s accuracy of +/- 0.4 over the range 0 < z < 6. This opportunity to break the redshift deadlock will provide an estimate of the global star formation history for luminous optically-obscured galaxies [L(FIR) > 3 x 10^12 Lsun] with an accuracy of 20 per cent.Comment: 14 pages, 22 figures, submitted to MNRAS, replaced with accepted versio

On the eigenproblems of PT-symmetric oscillators

We consider the non-Hermitian Hamiltonian H= -\frac{d^2}{dx^2}+P(x^2)-(ix)^{2n+1} on the real line, where P(x) is a polynomial of degree at most n \geq 1 with all nonnegative real coefficients (possibly P\equiv 0). It is proved that the eigenvalues \lambda must be in the sector | arg \lambda | \leq \frac{\pi}{2n+3}. Also for the case H=-\frac{d^2}{dx^2}-(ix)^3, we establish a zero-free region of the eigenfunction u and its derivative u^\prime and we find some other interesting properties of eigenfunctions.Comment: 21pages, 9 figure

CMB anisotropy predictions for a model of double inflation

We consider a double-inflationary model with two massive scalar fields interacting only gravitationally in the context of a flat cold dark matter (CDM) Universe. The cosmic microwave background (CMB) temperature anisotropies produced in this theory are investigated in great details for a window of parameters where the density fluctuation power spectrum P(k) is in good agreement with observations. The first Doppler (``acoustic'') peak is a crucial test for this model as well as for other models. For the ``standard'' values of the cosmological parameters of CDM, our model is excluded if the height of the Doppler peak is sensibly higher than about three times the Sachs-Wolfe plateau.Comment: 12 pages LaTeX using revtex, to be published in Phys. Rev.

Determination of Inflationary Observables by Cosmic Microwave Background Anisotropy Experiments

Inflation produces nearly Harrison-Zel'dovich scalar and tensor perturbation spectra which lead to anisotropy in the cosmic microwave background (CMB). The amplitudes and shapes of these spectra can be parametrized by $Q_S^2$, $r\equiv Q_T^2/Q_S^2$, $n_S$ and $n_T$ where $Q_S^2$ and $Q_T^2$ are the scalar and tensor contributions to the square of the CMB quadrupole and $n_S$ and $n_T$ are the power-lawspectral indices. Even if we restrict ourselves to information from angles greater than one third of a degree, three of these observables can be measured with some precision. The combination $130^{1-n_S}Q_S^2$ can be known to better than $\pm 0.3\%$. The scalar index $n_S$ can be determined to better than $\pm 0.02$. The ratio $r$ can be known to about $\pm 0.1$ for $n_S \simeq 1$ and slightly better for smaller $n_S$. The precision with which $n_T$ can be measured depends weakly on $n_S$ and strongly on $r$. For $n_S \simeq 1$ $n_T$ can be determined with a precision of about $\pm 0.056(1.5+r)/r$. A full-sky experiment with a $20'$beam using technology available today, similar to those being planned by several groups, can achieve the above precision. Good angular resolution is more important than high signal-to-noise ratio; for a given detector sensitivity and observing time a smaller beam provides significantly more information than a larger beam. The uncertainties in $n_S$ and $r$ are roughly proportional to the beam size. We briefly discuss the effects of uncertainty in the Hubble constant, baryon density, cosmological constant and ionization history.Comment: 28 pages of uuencoded postscript with 8 included figures. A postscript version is also available by anonymous ftp at ftp://astro.uchicago.edu/pub/astro/knox/fullsim.p