Malign catatonia, treatment-resistant benzodiazepine but treated successfully With electroconvulsive treatment: A case report

Catatonia is a neuropsychiatric syndrome that can occur in schizophrenia, major depression and general medical condition. It presents with decrease in psychomotor activity or increase in motor symptoms or a change in motor activity in time. It is known that acute catatonia and malign catatonia responds to benzodiazepine treatment to a great extent. Here, we report a case of acute and malign catatonia which did not respond to benzodiazepine treatment and treated successfully with electroconvulsive treatment. As we know, there are many case reports and studies about catatonia in our country, but our case is the first case which is resistant to benzodiazepine treatment although it has an acute beginning, we think that our case has a clinical importance in this aspect

A study on the effects of quetiapine on social cognitive functions of schizophrenia patients

Objective: The objective of this study is to investigate the effects of quetiapine on social cognitive functions of schizophrenia patients

Efficacy of aripiprazole augmentation in treatment resistant obsessive compulsive disorder: A preliminary report

Objective: To investigate efficacy of aripiprazole augmentation in treatment resistant obsessive compulsive disorder

Steroid induced psychosis and hypersexuality in adolescents: A case report

Steroid-induced psychotic disorder is an important adverse effect of steroid treatment and is characterized by hallucinations and delusions. Although it is known that steroid treatment and psychosis may result in hypersexuality in adults, this relationship is not reported in children and adolescents. Here, we report a case of an adolescent who developed psychosis due to steroid treatment and had hypersexuality as presenting symptom. We think that our case is the first in children and adolescent age group regarding its clinical presentation and treatment

Psychiatric assessment of children with nonsyndromic cleft lip and palate

Objective: The aim of the study was to determine whether children with nonsyndromic cleft lip and palate (NSCLP) are more likely to be diagnosed with psychiatric disorders and whether cleft-related factors are related to psychopathology

Investigating Predictors of Clozapine Response in Adolescents with Schizophrenia and Schizoaffective Disorder

Objectives: We aimed to determine the clinical predictors of clozapine response in patients with early-onset schizophrenia (EOS)/schizoaffective disorder and the effect of substance use disorder (SUD) on treatment outcomes. Methods: Medical records of patients with treatment-resistant EOS receiving clozapine were identified for data analysis dated between January 2015 and April 2020. Patients on clozapine were followed in an inpatient unit of a tertiary care mental health hospital. Using the Positive and Negative Symptom Scale (PANSS), >= 30% reduction was defined as the response criteria after clozapine treatment. Results: Of 50 subjects (age: 16.3 +/- 1.3 years, 36.0% female), 22 subjects (44.0%) met the defined response criteria. Clozapine responder (CLZ-R) and clozapine nonresponder (CLZ-NR) groups were similar regarding age at illness onset, sex, and duration of untreated psychosis. The CLZ-R group had higher baseline positive PANSS scores (24.8 +/- 8.1 vs. 17.1 +/- 6.6, p = 0.001, d = 1.0) and total PANSS scores (94.8 +/- 17.2 vs. 80.1 +/- 19.8, p = 0.008, d = 0.8) compared with the CLZ-NR counterparts. The duration of hospital stay was longer in the CLZ-NR group (122.3 +/- 48.2 vs. 87.3 +/- 36.2 days, p = 0.007). Among 32 male patients, the presence of SUD (n = 9, 28.1%) was associated with a less reduction in total PANSS scores (F = 7.5, p = 0.010) and higher levels of positive symptoms at the end of the treatment (12.8 +/- 4.1 vs. 18.8 +/- 7.4, p = 0.006, d = 1.0). Synthetic cannabinoids were the most common substance type used among males with treatment-refractory EOS (25.0%). Conclusions: Our results did not support the role of sociodemographic variables in clozapine response. Positive symptoms and SUD yielded a prognostic value in patients receiving clozapine

Epidemiology of depression in an urban population of Turkish children and adolescents

Background: In Turkey, studies of childhood depression have been limited to those using only scales

Psychiatric disorders and their association with burn-related factors in children with burn injury

BACKGROUND: The aim of this study was to assess psychiatric disorders and their association with burn-related factors in a population of Turkish children with burns