Uso de materiales de evaluación e intervención psicológica adaptados a personas con discapacidad como recurso didáctico innovador en el ámbito de la Psicología Clínica

Depto. de Personalidad, Evaluación y Psicología ClínicaFac. de PsicologíaFALSEsubmitte

Informe sobre el impacto físico y psicológico de la situación derivada de la COVID-19

El objetivo del proyecto fue estudiar el impacto físico y psicológico sobre la población de la situación de crisis sanitaria y de confinamiento derivada de la COVID-19. Un total de 3253 personas procedentes de toda España participaron en el estudio. La recogida de datos se realizó en formato on-line durante las 3 primeras semanas de confinamiento (15 marzo a 6 de abril 2020). Se aplicaron los siguientes instrumentos: Cuestionario de salud del paciente (PHQ-15), Escala Hospitalaria de Ansiedad y Depresión (HADS) y Escala de resiliencia Connor-Davidson (CD-RISC-10).Depto. de Personalidad, Evaluación y Psicología ClínicaFac. de PsicologíaFALSEunpu

Propuesta de aplicación de metodologías activas e inductivas en la enseñanza del Máster en Psicología General Sanitaria

Preparación de clases interactivas sobre algunos temas del Máster en Psicología General Sanitaria, siguiendo metodologías activas e inductivas en modelos educativos de aula inversa, utilizando estrategias de desarrollo profesional colaborativo

Substance use, stressful life events and mental health: A longitudinal study among homeless women in Madrid (Spain)

The objectives of this study were: (1) to assess the prevalence of substance use among homeless women; (2) to examine the correlates for drug abuse; (3) to analyze linkages between early stressful life events, drug abuse and mental health. The methodology was a longitudinal study of women homeless in Madrid (Spain), who were followed for a 24 months period. There were 138 participants interviewed at baseline and 73 participants interviewed at follow-up. We ran bivariate and multivariate analysis to examine the correlates for drug abuse. We also performed path analysis to test the interconnections between stressful life events, drug abuse and mental health. The results showed that tobacco, sedatives and alcohol were the most widely used substances in the previous month (70.1%, 48.6% and 36.2%, respectively). Women who abused drugs were more likely to be younger, report adverse experiences during childhood, have engaged in prostitution, and ever-attempted suicide. Path analysis provided support for our hypothesis that early stressful life events increased the vulnerability for subsequent negative outcomes amongst homeless women. These findings have significant implications for the understanding of how orienting prevention and intervention programs for homeless women in Spai

“Pasapalabra” de la Psicología Clínica: Una herramienta de aprendizaje basada en el juego

Depto. de Personalidad, Evaluación y Psicología ClínicaFac. de PsicologíaFALSEsubmitte

“Pasapalabra” de la Psicología Clínica 2: Una herramienta de aprendizaje basada en el juego

El objetivo general del proyecto de innovación “Pasapalabra” de la Psicología Clínica 2: Una herramienta de aprendizaje basada en el juego era potenciar el aprendizaje activo de términos y conceptos relativos a la Psicología Clínica a través de una herramienta basada en las nuevas tecnologías y el juego. Se basa en el popular concurso “Pasapalabra”, concretamente en la prueba final denominada “El rosco”, en la cual el/la participante debe averiguar palabras a partir de su definición y teniendo como pista la letra inicial de la palabra o una letra contenida en ella. Este proyecto surgió como la continuación del proyecto de innovación concedido en la convocatoria PIMCD 2018-2019. Su propósito era dar continuidad, profundizar y divulgar el proyecto “Pasapalabra” de la Psicología Clínica

Proyecto Puentes: conectando la universidad con la salud mental comunitaria

Se presenta la memoria del Proyecto Puentes, cuya finalidad es explorar e implementar vías de participación entre la comunidad universitaria y las personas con problemas de salud mental. Es decir, tender puentes entre lo académico y la realidad de esas personas, con el propósito de conseguir una fuente de aprendizaje significativo para el estudiantado de la UCM, pero también herramientas útiles en los procesos de recuperación e integración de las personas con problemáticas de salud mental.Depto. de Personalidad, Evaluación y Psicología ClínicaFac. de PsicologíaFALSEsubmitte

Standardized incidence ratios and risk factors for cancer in patients with systemic sclerosis: Data from the Spanish Scleroderma Registry (RESCLE)

Aim: Patients with systemic sclerosis (SSc) are at increased risk of cancer, a growing cause of non-SSc-related death among these patients. We analyzed the increased cancer risk among Spanish patients with SSc using standardized incidence ratios (SIRs) and identified independent cancer risk factors in this population. Material and methods: Spanish Scleroderma Registry data were analyzed to determine the demographic characteristics of patients with SSc, and logistic regression was used to identify cancer risk factors. SIRs with 95% confidence intervals (CIs) relative to the general Spanish population were calculated. Results: Of 1930 patients with SSc, 206 had cancer, most commonly breast, lung, hematological, and colorectal cancers. Patients with SSc had increased risks of overall cancer (SIR 1.48, 95% CI 1.36-1.60; P < 0.001), and of lung (SIR 2.22, 95% CI 1.77-2.73; P < 0.001), breast (SIR 1.31, 95% CI 1.10-1.54; P = 0.003), and hematological (SIR 2.03, 95% CI 1.52-2.62; P < 0.001) cancers. Cancer was associated with older age at SSc onset (odds ratio [OR] 1.22, 95% CI 1.01-1.03; P < 0.001), the presence of primary biliary cholangitis (OR 2.35, 95% CI 1.18-4.68; P = 0.015) and forced vital capacity <70% (OR 1.8, 95% CI 1.24-2.70; P = 0.002). The presence of anticentromere antibodies lowered the risk of cancer (OR 0.66, 95% CI 0.45-0.97; P = 0.036). Conclusions: Spanish patients with SSc had an increased cancer risk compared with the general population. Some characteristics, including specific autoantibodies, may be related to this increased risk

Complement component C4 structural variation and quantitative traits contribute to sex-biased vulnerability in systemic sclerosis

Altres ajuts: Fondo Europeo de Desarrollo Regional (FEDER), "A way of making Europe".Copy number (CN) polymorphisms of complement C4 play distinct roles in many conditions, including immune-mediated diseases. We investigated the association of C4 CN with systemic sclerosis (SSc) risk. Imputed total C4, C4A, C4B, and HERV-K CN were analyzed in 26,633 individuals and validated in an independent cohort. Our results showed that higher C4 CN confers protection to SSc, and deviations from CN parity of C4A and C4B augmented risk. The protection contributed per copy of C4A and C4B differed by sex. Stronger protection was afforded by C4A in men and by C4B in women. C4 CN correlated well with its gene expression and serum protein levels, and less C4 was detected for both in SSc patients. Conditioned analysis suggests that C4 genetics strongly contributes to the SSc association within the major histocompatibility complex locus and highlights classical alleles and amino acid variants of HLA-DRB1 and HLA-DPB1 as C4-independent signals

Treatment with tocilizumab or corticosteroids for COVID-19 patients with hyperinflammatory state: a multicentre cohort study (SAM-COVID-19)

Objectives: The objective of this study was to estimate the association between tocilizumab or corticosteroids and the risk of intubation or death in patients with coronavirus disease 19 (COVID-19) with a hyperinflammatory state according to clinical and laboratory parameters. Methods: A cohort study was performed in 60 Spanish hospitals including 778 patients with COVID-19 and clinical and laboratory data indicative of a hyperinflammatory state. Treatment was mainly with tocilizumab, an intermediate-high dose of corticosteroids (IHDC), a pulse dose of corticosteroids (PDC), combination therapy, or no treatment. Primary outcome was intubation or death; follow-up was 21 days. Propensity score-adjusted estimations using Cox regression (logistic regression if needed) were calculated. Propensity scores were used as confounders, matching variables and for the inverse probability of treatment weights (IPTWs). Results: In all, 88, 117, 78 and 151 patients treated with tocilizumab, IHDC, PDC, and combination therapy, respectively, were compared with 344 untreated patients. The primary endpoint occurred in 10 (11.4%), 27 (23.1%), 12 (15.4%), 40 (25.6%) and 69 (21.1%), respectively. The IPTW-based hazard ratios (odds ratio for combination therapy) for the primary endpoint were 0.32 (95%CI 0.22-0.47; p < 0.001) for tocilizumab, 0.82 (0.71-1.30; p 0.82) for IHDC, 0.61 (0.43-0.86; p 0.006) for PDC, and 1.17 (0.86-1.58; p 0.30) for combination therapy. Other applications of the propensity score provided similar results, but were not significant for PDC. Tocilizumab was also associated with lower hazard of death alone in IPTW analysis (0.07; 0.02-0.17; p < 0.001). Conclusions: Tocilizumab might be useful in COVID-19 patients with a hyperinflammatory state and should be prioritized for randomized trials in this situatio