8,444 research outputs found
ATLAS RPC offline monitoring and data quality assessment
In this work several aspects of ATLAS RPC offline monitoring and data quality
assessment are illustrated with cosmics data selected by RPC trigger. These
correspond to trigger selection, front-end mapping, detection efficiency and
occupancy, which are studied in terms of low level quantities such as: RPC
off-line hits and standalone tracks. The tools and techniques presented are
also extended to the forthcoming LHC p-p beam collisions.Comment: Poster section at ICHEP08, Philadelphia, USA, July 2008. 3 pages,
LaTeX, 3 eps figure
Measuring walking accessibility to public transport for the elderly: the case of Naples
Demographic ageing represents an essential challenge for local authorities and public transport providers. Decision-makers should not ignore the speci c needs of this weak segment of the population and should implement appropriate policies. This paper develops a GIS-based method to analyse public transport accessibility of elderly people to support policies and planning strategies. To test the proposed method, we propose an application to the city of Naples in Italy. We selected this study case because it represents an example of high population density, complex urban structure and low level of quality of life, especially for the elderly. The application to the city of Naples showed that the urban accessibility changes dramatically for different age segments. Results also reveal patterns of public transport coverage that are signi cantly low particularly in suburban settings. The structure of this paper is organised into four sections: in the rst section, we introduce the main topic of mobility of elderly; in the second section, we describe and discuss the GIS-based method proposed; in the third section, we report on the application to the city of Naples; in the last section, we analyse the results and discuss future research developments
Eradication of Candida albicans persister cell biofilm by the membranotropic peptide gH625
Biofilm formation poses an important clinical trouble due to resistance to antimicrobial agents; therefore, there is an urgent demand for new antibiofilm strategies that focus on the use of alternative compounds also in combination with conventional drugs. Drug-tolerant persisters are present in Candida albicans biofilms and are detected following treatment with high doses of amphotericin B. In this study, persisters were found in biofilms treated with amphotericin B of two clinical isolate strains, and were capable to form a new biofilm in situ. We investigated the possibility of eradicating persister-derived biofilms from these two Candida albicans strains, using the peptide gH625 analogue (gH625-M). Confocal microscopy studies allowed us to characterize the persister-derived biofilm and understand the mechanism of interaction of gH625-M with the biofilm. These findings confirm that persisters may be responsible for Candida biofilm survival, and prove that gH625-M was very effective in eradicating persister-derived biofilms both alone and in combination with conventional antifungals, mainly strengthening the antibiofilm activity of fluconazole and 5-flucytosine. Our strategy advances our insights into the development of effective antibiofilm therapeutic approaches
New Optimization Methods for Converging Perturbative Series with a Field Cutoff
We take advantage of the fact that in lambda phi ^4 problems a large field
cutoff phi_max makes perturbative series converge toward values exponentially
close to the exact values, to make optimal choices of phi_max. For perturbative
series terminated at even order, it is in principle possible to adjust phi_max
in order to obtain the exact result. For perturbative series terminated at odd
order, the error can only be minimized. It is however possible to introduce a
mass shift in order to obtain the exact result. We discuss weak and strong
coupling methods to determine the unknown parameters. The numerical
calculations in this article have been performed with a simple integral with
one variable. We give arguments indicating that the qualitative features
observed should extend to quantum mechanics and quantum field theory. We found
that optimization at even order is more efficient that at odd order. We compare
our methods with the linear delta-expansion (LDE) (combined with the principle
of minimal sensitivity) which provides an upper envelope of for the accuracy
curves of various Pade and Pade-Borel approximants. Our optimization method
performs better than the LDE at strong and intermediate coupling, but not at
weak coupling where it appears less robust and subject to further improvements.
We also show that it is possible to fix the arbitrary parameter appearing in
the LDE using the strong coupling expansion, in order to get accuracies
comparable to ours.Comment: 10 pages, 16 figures, uses revtex; minor typos corrected, refs. adde
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