B-vitamin consumption and the prevalence of diabetes and obesity among the US adults: population based ecological study

<p>Abstract</p> <p>Background</p> <p>The global increased prevalence of obesity and diabetes occurred after the worldwide spread of B-vitamins fortification, in which whether long-term exposure to high level of B vitamins plays a role is unknown. Our aim was to examine the relationships between B-vitamins consumption and the obesity and diabetes prevalence.</p> <p>Methods</p> <p>This population based ecological study was conducted to examine possible associations between the consumption of the B vitamins and macronutrients and the obesity and diabetes prevalence in the US population using the per capita consumption data from the US Economic Research Service and the prevalence data from the US Centers for Disease Control and Prevention.</p> <p>Results</p> <p>The prevalences of diabetes and adult obesity were highly correlated with per capita consumption of niacin, thiamin and riboflavin with a 26-and 10-year lag, respectively (<it>R</it>²= 0.952, 0.917 and 0.83 for diabetes, respectively, and <it>R</it>²= 0.964, 0.975 and 0.935 for obesity, respectively). The diabetes prevalence increased with the obesity prevalence with a 16-year lag (<it>R</it>²= 0.975). The relationships between the diabetes or obesity prevalence and per capita niacin consumption were similar both in different age groups and in male and female populations. The prevalence of adult obesity and diabetes was highly correlated with the grain contribution to niacin (<it>R</it>²= 0.925 and 0.901, respectively), with a 10-and 26-year lag, respectively. The prevalence of obesity in US adults during 1971-2004 increased in parallel with the increase in carbohydrate consumption with a 10-year lag. The per capita energy and protein consumptions positively correlated with the obesity prevalence with a one-year lag. Moreover, there was an 11-year lag relationship between per capita energy and protein consumption and the consumption of niacin, thiamin and riboflavin (<it>R</it>²= 0.932, 0.923 and 0.849 for energy, respectively, and <it>R</it>²= 0.922, 0.878 and 0.787 for protein, respectively).</p> <p>Conclusions</p> <p>Long-term exposure to high level of the B vitamins may be involved in the increased prevalence of obesity and diabetes in the US in the past 50 years. The possible roles of B-vitamins fortification and excess niacin consumption in the increased prevalence of obesity and diabetes were discussed.</p

(Z)-5-(4-Fluoro­benzyl­idene)-1,3-thia­zolidine-2,4-dione

In the title compound, C10H6FNO2S, the benzene and thia­zolidine rings make a dihedral angle of 7.52 (3)°. Intra­molecular C—H⋯O and C—H⋯S hydrogen bonds result in the formation of nearly planar five- and six-membered rings; the adjacent rings are nearly coplanar. In the crystal structure, inter­molecular N—H⋯O hydrogen bonds link the mol­ecules

5-Bromo-2-methyl­pyridine N-oxide

In the mol­ecule of the title compound, C6H6BrNO, the methyl C and oxide O atoms lie in the pyridine ring plane, while the Br atom is displaced by 0.103 (3) Å. In the crystal structure, inter­molecular C—H⋯O hydrogen bonds link the mol­ecules into centrosymmetric dimers

A Search for Double-peaked narrow emission line Galaxies and AGNs in the LAMOST DR1

LAMOST has released more than two million spectra, which provide the opportunity to search for double-peaked narrow emission line (NEL) galaxies and AGNs. The double-peaked narrow-line profiles can be well modeled by two velocity components, respectively blueshifted and redshifted with respect to the systemic recession velocity. This paper presents 20 double-peaked NEL galaxies and AGNs found from LAMOST DR1 using a search method based on multi-gaussian fit of the narrow emission lines. Among them, 10 have already been published by other authors, either listed as genuine double-peaked NEL objects or as asymmetric NEL objects, the remaining 10 being first discoveries. We discuss some possible origins for double-peaked narrow-line features, as interaction between jet and narrow line regions, interaction with companion galaxies and black hole binaries. Spatially resolved optical imaging and/or follow-up observations in other spectral bands are needed to further discuss the physical mechanisms at work.Comment: 17 pages, 5figures, 4 tables, accepted by RA

Methyl 4-chloro-3-nitro­benzoate

In the title compound, C8H6ClNO4, the mol­ecules are linked by C—H⋯O inter­actions to form a chain parallel to the a axis. The chains are further connected by slipped π–π stacking between symmetry-related benzene rings, with a centroid-to-centroid distance of 3.646 (2) Å and an inter­planar distance of 3.474 Å, resulting in an offset of 1.106 Å