233 research outputs found

    Balagueró, Plaza y Cerdá : La Nueva Escuela de Barcelona

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    Estudio de la descomposición térmica de residuos agrícolas de cultivo del banano

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    En este trabajo se ha realizado un estudio de las principales características que presenta el raquis de banano tras someterlo a diferentes experimentos de pirólisis

    Dimensionamiento de sistemas fotovoltaicos con baterías para Peak shaving en aplicaciones residenciales

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    El siguiente documento versa de un estudio del dimensionamiento de una instalación fotovoltaica con baterías en una vivienda, la cual está conectada a la red, con el fin de aplicar la técnica de Peak shaving. Esta técnica corresponde al recorte de picos en la demanda de energía a la red para reducir así los costes operacionales que pueden ir asociados en los periodos de mayor demanda, además de facilitar el control de los flujos de potencia en la red por parte del operador del sistema. Así pues, a lo largo del estudio se analizará la influencia que los tamaños de paneles fotovoltaicos y/o baterías tienen sobre los parámetros de red más característicos y se buscará los tamaños óptimos para la aplicación de Peak shaving. Para el caso de introducir baterías en la instalación se propondrán diferentes métodos de gestión de la carga y descarga de las mismas con el fin de aplicar de manera más eficaz el recorte de picos. Se comparará para los diferentes métodos la vida útil de las baterías mediante el modelo de conteo Rainflow. Por último, se extraerán las diferentes conclusiones que sirvan de base al diseño real de una instalación con el objetivo de aplicar el Peak shaving

    Sexual communication in day-flying Lepidoptera with special reference to castniids or 'butterfly-moths'

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    Butterflies and moths are subject to different evolutionary pressures that affect several aspects of their behaviour and physiology, particularly sexual communication. Butterflies are day-flying insects (excluding hedylids) whose partner-finding strategy is mainly based on visual cues and female butterflies having apparently lost the typical sex pheromone glands. Moths, in contrast, are mostly night-flyers and use female-released long-range pheromones for partner-finding. However, some moth families are exclusively day-flyers, and therefore subject to evolutionary pressures similar to those endured by butterflies. Among them, the Castniidae, also called 'butterfly-moths' or 'sun-moths', behave like butterflies and, thus, castniid females appear to have also lost their pheromone glands, an unparallel attribute in the world of moths. In this paper, we review the sexual communication strategy in day-flying Lepidoptera, mainly butterflies (superfamily Papilionoidea), Zygaenidae and Castniidae moths, and compare their mating behaviour with that of moth families of nocturnal habits, paying particular attention to the recently discovered butterfly-like partner-finding strategy of castniids and the fascinating facts and debates that led to its discovery

    Factores de riesgo asociados a desgarros Vulvoperineales en puérperas atendidas en el Hospital Regional de Loreto, Enero – Abril del 2013

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    This research entitled "Risk factors associated with postpartum tears in vulvoperineal treated at the Regional Hospital of Loreto, January-April 2013" ; retrospective correlational quantitative study aimed to identify risk factors associated with vulvoperineal tears, the population consisted of all Postpartum women who had diagnosis of vulvo-perineal tear postpartum amounting to 115. The information was obtained from perinatal clinical histories and 2000 Perinatal Information system recorded in formats adapted to the study and organized in a computerized database with Microsoft Excel 2011 software. The results, 115 vulvoperineal tears in four months, the study population was characterized as cohabiting 71.3 % (82 ) , complete primary education 37.3 % (43 ) 23.4 % and incomplete ( 27), 54.7 % of urban origin (urban ) housewife occupancy 84.3 % (97 ) . The salient maternal risk factors are age 21 to 30 years, mild anemia, the horizontal position and status of gilts, as risk factors for delivery I have instrumental delivery , episiotomy and weight to 4000g RN 3501 We conclude that maternal factors : age ( x2 = 14.03) , anemia ( x2 = 12.75) , maternal position ( x2 = 8.03) and parity ( x2 = 13.69 ); and delivery factors , use of episiotomy ( x2 = 17.84 ) and birth weight ( x2 = 13.91 ) , are associated with it Vulvo tear in puerperal women attended the Loreto Regional Hospital during the months of January to April 2013.La presente investigación titulada “Factores de Riesgo Asociados a Desgarros Vulvoperineales en Puérperas atendidas en el Hospital Regional de Loreto, Enero – Abril 2013”; estudio cuantitativo correlacional retrospectivo, cuyo Objetivo fue identificar los factores de riesgo asociados a desgarros Vulvoperineales, la población estuvo constituida por todas las puérperas que Presentaron diagnóstico de desgarro vulvoperineal post parto el mismo que Asciende a 115. La información fue obtenida de las historias clínicas perinatales Y el Sistema Información Perinatal 2000, se registró en los formatos adaptados Para el estudio y organizado en una base de datos automatizada con el Software Microsoft Excel 2011. Los resultados, 115 desgarros vulvoperineales en cuatro meses, la población Estudio se caracterizó por ser conviviente 71.3% (82), de educación primaria completa 37.3% (43) e incompleta 23.4% (27), de procedencia urbana 54.7% (urbana), de Ocupación ama de casa 84,3% (97). Los factores de riesgos maternos resaltantes son La edad de 21 a 30 años, anemia leve, la posición horizontal y la condición de Primíparas, como factores de riesgo del parto tenemos parto instrumental, episiotomía Y peso 3501 a 4000g del RN. Se concluye que los factores maternos: edad (x2=14.03), anemia (x2=12.75), Posición de la madre (x2=8.03) y paridad (x2=13.69); y los factores del parto, uso de Episiotomía media (x2=17.84) y peso del recién nacido (x2=13.91), están asociados Con él desgarro vulvoperineal en puérperas atendidas en el Hospital Regional de Loreto, durante los meses de enero a abril del 2013.Tesi

    Using dried orange pulp in the diet of dairy goats: effects on milk yield and composition and blood parameters of dams and growth performance and carcass quality of kids

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    Although dried orange pulp (DOP) may conveniently replace cereals in ruminant diets, few studies have considered similar diet substitution for goats. We hypothesised that DOP could replace cereal-based concentrate in goat diets without detrimental effects on growth performance and carcass quality of suckling kids and milk performance and blood biochemical parameters of dams in early lactation. We also hypothesised that DOP substitution may increase the levels of antioxidants, such as phenolic compounds and vitamin E, in milk and improve its total antioxidant capacity (TAC). Therefore, 44 primiparous Payoya dairy goats were allocated to three experimental groups, each fed a different diet: control (CD, n = 14) based on a commercial concentrate with alfalfa hay as forage; and DOP40 (n = 16) in which 40% and DOP80 (n = 14) in which 80% of the cereal in the concentrate were replaced by DOP. The experiment lasted from the final month of pregnancy to 55 days postpartum. The DOP diets did not affect suckling kids’ carcass quality, but at 28 days, led to improvement in live weight (LW) and average daily gain (ADG) from birth, although no differences were found between DOP40 and DOP80 (for CD, DOP40 and DOP80, LW at 28 days was 8.00, 8.58 and 8.34 kg and ADG was 184, 199 and 195 g/day, respectively). Diet had no significant effect on milk yield (average daily milk yield and total yield at 55 days were 1.66 l/day and 90.6 l, respectively) and commercial and fatty acid composition. Nevertheless, α-tocopherol, total phenolic compound (TPC) and TAC concentration in milk increased with substitution of cereals by DOP (for CD, DOP40 and DOP80, concentration of α-tocopherol was 21.7, 32.8 and 42.3 μg/100 g, TPCs was 63.5, 84.1 and 102 mg gallic acid equivalents/l, and TAC was 6.63, 11.1 and 12.8 μmol Trolox equivalents/ml, respectively). Every plasma biochemistry parameter considered was within reference values for healthy goats; therefore, no pathological effect was detected for these variables due to dietary treatment. However, DOP diets caused a reduction in plasmatic creatine kinase and aspartate aminotransferase, implying reduced oxidative damage to muscles. In conclusion, DOP may be an interesting alternative to cereals in early lactation goat diets for increasing farmers’ income and the healthy antioxidant capacity of milk

    Desarrollo de geles bioactivos basados en residuos de la industria del arroz

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    La industria arrocera produce aproximadamente unos 100 millones de toneladas de residuos cada año. Aunque estos residuos tengan un alto contenido proteico, habitualmente se incineran debido a su alto poder calorífico. Sin embargo, existe una continua y creciente demanda de fuentes de proteína con el fin de poder satisfacer las necesidades de alimentación de la creciente población mundial. Una alternativa interesante sería el uso de concentrados proteicos provenientes de estos residuos para desarrollar productos alimentarios. En este sentido, se ha comprobado que la obtención de hidrolizados proteicos a partir de los concentrados proteicos puede ser una vía altamente interesante, aumentando la funcionalidad de estos sistemas. Por otra parte, en el caso de los productos alimentarios, las propiedades mecánicas no son las únicas que importan. De especial relevancia son las propiedades antioxidantes de estos productos. La evaluación de la capacidad antioxidante de estos sistemas puede llevarse a cabo mediante el empleo de diferentes técnicas. La presente contribución hace uso de un concentrado proteico de arroz (RPC) y dos hidrolizados (RPHA and RPHB) para el desarrollo de geles alimentarios. La caracterización llevada a cabo comprende tanto a la estructura de los sistemas, como a las de las propiedades antioxidantes de los mismos.Rice industry produces around 100 million tons of wastes every year. Although, these wastes generally exhibits a high protein content, they are burned due to its high calorific value. However, scientific community claims continuously for new protein sources in order to satisfy worldwide food requirements. In this sense, one alternative could be the use of protein concentrates from protein surpluses and wastes to develop new food products. Additionally, the use of protein hydrolysates could be very relevant since the functionality of protein may increase. Otherwise, not only the functionality of proteins is relevant in food products, but also the bioactive properties of them is a key factor. Among these bioactive properties, the evaluation of antioxidant properties of food products could involve the increase in value of these by-products. This work deals with the evaluation of a protein concentrate (RPC) and two different protein hydrolysates (RPHA and RPHB) in order to develop food-grade gels. The characterisation carried out include mechanical properties and antioxidant activity of the final gels.Plan Propio de la Universidad de Sevilla Proyecto: 2017/0000096

    Obatoclax and Paclitaxel Synergistically Induce Apoptosis and Overcome Paclitaxel Resistance in Urothelial Cancer Cells

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    Paclitaxel is a treatment option for advanced or metastatic bladder cancer after the failure of first-line cisplatin and gemcitabine, although resistance limits its clinical benefits. Mcl-1 is an anti-apoptotic protein that promotes resistance to paclitaxel in different tumors. Obatoclax, a BH3 mimetic of the Bcl-2 family of proteins, antagonizes Mcl-1 and hence may reverse paclitaxel resistance in Mcl-1-overexpressing tumors. In this study, paclitaxel-sensitive 5637 and -resistant HT1197 bladder cancer cells were treated with paclitaxel, obatoclax, or combinations of both. Apoptosis, cell cycle, and autophagy were measured by Western blot, flow cytometry, and fluorescence microscopy. Moreover, Mcl-1 expression was analyzed by immunohistochemistry in bladder carcinoma tissues. Our results confirmed that paclitaxel alone induced Mcl-1 downregulation and apoptosis in 5637, but not in HT1197 cells; however, combinations of obatoclax and paclitaxel sensitized HT1197 cells to the treatment. In obatoclax-treated 5637 and obatoclax + paclitaxel-treated HT1197 cells, the blockade of the autophagic flux correlated with apoptosis and was associated with caspase-dependent cleavage of beclin-1. Obatoclax alone delayed the cell cycle in 5637, but not in HT1197 cells, whereas combinations of both retarded the cell cycle and reduced mitotic slippage. In conclusion, obatoclax sensitizes HT1197 cells to paclitaxel-induced apoptosis through the blockade of the autophagic flux and effects on the cell cycle. Furthermore, Mcl-1 is overexpressed in many invasive bladder carcinomas, and it is related to tumor progression, so Mcl-1 expression may be of predictive value in bladder cancer.España, Sistema Público Andaluz Biobanco y ISCIII-Red de Biobancos PT17/0015/004

    Simulation of P systems with active membranes on CUDA

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    P systems or Membrane Systems provide a high-level computational modelling framework that combines the structure and dynamic aspects of biological systems in a relevant and understandable way. They are inherently parallel and non-deterministic computing devices. In this article, we discuss the motivation, design principles and key of the implementation of a simulator for the class of recognizer P systems with active membranes running on a (GPU). We compare our parallel simulator for GPUs to the simulator developed for a single central processing unit (CPU), showing that GPUs are better suited than CPUs to simulate P systems due to their highly parallel nature.Ministerio de Educación y Ciencia TIN2006-13425Junta de Andalucía P08–TIC-0420
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