Numerics of boundary-domain integral and integro-differential equations for BVP with variable coefficient in 3D

This is the post-print version of the article. The official published version can be accessed from the links below - Copyright @ 2013 Springer-VerlagA numerical implementation of the direct boundary-domain integral and integro-differential equations, BDIDEs, for treatment of the Dirichlet problem for a scalar elliptic PDE with variable coefficient in a three-dimensional domain is discussed. The mesh-based discretisation of the BDIEs with tetrahedron domain elements in conjunction with collocation method leads to a system of linear algebraic equations (discretised BDIE). The involved fully populated matrices are approximated by means of the H-Matrix/adaptive cross approximation technique. Convergence of the method is investigated.This study is partially supported by the EPSRC grant EP/H020497/1:"Mathematical Analysis of Localised-Boundary-Domain Integral Equations for Variable-Coefficients Boundary Value Problems"

Mechanics of lipid bilayer junctions affecting the size of a connecting lipid nanotube

In this study we report a physical analysis of the membrane mechanics affecting the size of the highly curved region of a lipid nanotube (LNT) that is either connected between a lipid bilayer vesicle and the tip of a glass microinjection pipette (tube-only) or between a lipid bilayer vesicle and a vesicle that is attached to the tip of a glass microinjection pipette (two-vesicle). For the tube-only configuration (TOC), a micropipette is used to pull a LNT into the interior of a surface-immobilized vesicle, where the length of the tube L is determined by the distance of the micropipette to the vesicle wall. For the two-vesicle configuration (TVC), a small vesicle is inflated at the tip of the micropipette tip and the length of the tube L is in this case determined by the distance between the two interconnected vesicles. An electrochemical method monitoring diffusion of electroactive molecules through the nanotube has been used to determine the radius of the nanotube R as a function of nanotube length L for the two configurations. The data show that the LNT connected in the TVC constricts to a smaller radius in comparison to the tube-only mode and that tube radius shrinks at shorter tube lengths. To explain these electrochemical data, we developed a theoretical model taking into account the free energy of the membrane regions of the vesicles, the LNT and the high curvature junctions. In particular, this model allows us to estimate the surface tension coefficients from R(L) measurements

Localized boundary-domain singular integral equations of Dirichlet problem for self-adjoint second order strongly elliptic PDE systems

The paper deals with the three dimensional Dirichlet boundary value problem (BVP) for a second order strongly elliptic self-adjoint system of partial di erential equations in the divergence form with variable coe cients and develops the integral potential method based on a localized parametrix. Using Green's representation formula and properties of the localized layer and volume potentials, we reduce the Dirichlet BVP to a system of localized boundary-domain integral equations (LBDIEs). The equivalence between the Dirichlet BVP and the corresponding LBDIE system is studied. We establish that the obtained localized boundary-domain integral operator belongs to the Boutet de Monvel algebra. With the help of the Wiener-Hopf factorization method we investigate corresponding Fredholm properties and prove invertibility of the localized operator in appropriate Sobolev (Bessel potential) spaces.This research was supported by the grants EP/H020497/1: "Mathematical Analysis of Localized Boundary-Domain Integral Equations for Variable-Coeff cient Boundary Value Problems" and EP/M013545/1: "Mathematical Analysis of Boundary-Domain Integral Equations for Nonlinear PDEs", from the EPSRC, UK, and by the grant of the Shota Rustaveli National Science Foundation FR/286/5-101/13, 2014- 2017: "Investigation of dynamical mathematical models of elastic multi-component structures with regard to fully coupled thermo-mechanical and electro-magnetic fields"

Analysis of segregated boundary-domain integral equations for BVPs with non-smooth coefficients on Lipschitz domains

Segregated direct boundary-domain integral equations (BDIEs) based on a parametrix and associated with the Dirichlet and Neumann boundary value problems for the linear stationary diffusion partial differential equation with a variable Hölder-continuous coefficients on Lipschitz domains are formulated. The PDE right-hand sides belong to the Sobolev (Bessel potential) space Hs−2(Ω ) or H˜s−2(Ω ) , 12<s<32, when neither strong classical nor weak canonical co-normal derivatives are well defined. Equivalence of the BDIEs to the original BVP, BDIE solvability, solution uniqueness/non-uniqueness, and the Fredholm property and invertibility of the BDIE operators are analysed in appropriate Sobolev spaces. It is shown that the BDIE operators for the Neumann BVP are not invertible; however, some finite-dimensional perturbations are constructed leading to invertibility of the perturbed (stabilised) operators.EPSR

A convolution thresholding scheme for the Willmore flow

A convolution thresholding scheme fro geometric Willmore flows is suggested and the consistency is proved