МЕТОДЫ ДИАГНОСТИКИ СТОРОЖЕВОГО ЛИМФАТИЧЕСКОГО УЗЛА У БОЛЬНЫХ РАКОМ МОЛОЧНОЙ ЖЕЛЕЗЫ

Objective: to provide various methods for sentinel lymph node detection considering their advantages and disadvantages.Material and Methods. The search of the relevant articles published in Pubmed, MedLine, RINTs, etc. database was conducted. 49 publications from 1970 to 2018 were analyzed.Results. Currently, sentinel lymph node biopsy (SLN biopsy) has become a worthy alternative to traditional lymphatic surgery for early breast cancer. SLN biopsy significantly decreases the number of postoperative complications caused by lymphadenectomy and improves the quality of life of cancer patients. So far, a large number of SLN detection techniques have accumulated. Each of these techniques has its own advantages and disadvantages.Conclusion. Despite a large number of SLN detection methods, the question of the optimal technique is currently debatable. Цель исследования – представить различные методы диагностики сторожевых лимфатических узлов, рассмотрев их достоинства и недостатки.Материал и методы. Проведен поиск статей, опубликованных в базах Pubmed, MedLine, РИНЦ, РГБ за 1970–2018 гг. Из 150 проанализированных публикаций в обзор вошли 50.Результаты. В настоящее время биопсия сторожевого лимфатического узла (СЛУ) стала достойной альтернативой традиционной хирургии на лимфатических путях при раннем раке молочной железы (РМЖ). Благодаря данной методике снизилось количество послеоперационных осложнений, вызванных лимфодиссекцией, а качество жизни больных значительно возросло. С момента появления и до настоящего времени накопилось большое количество техник определения СЛУ, каждая из которых имеет свои плюсы и минусы.Заключение. Несмотря на большое количество методов детекции СЛУ, вопрос об оптимальной технике в настоящее время остается дискуссионным.

Strategies of developers to housing supply within framework of project financing

The problem of providing comfortable and affordable housing for Russian citizens as a national goal has gained an impetus to solution after the introduction at the legislative level of project financing for housing construction using escrow accounts. The application of this new method of financing to the decision-making algorithm of a developer requires mathematical modeling of the economic ratios of the main indicators of the developer’s activities, taking into account the interests of other subjects in the housing construction sector: banks and population. The approach proposed by the authors is aimed primarily at expanding the supply in the housing market. We have formalized the possible sale strategies of the developer using a matrix approach in varying prices and the number of meters sold at different stages of construction, as well as interest rates for bank crediting, depending on the degree of escrow accounts accumulation. Testing the model has shown that developers should face serious problems related to increasing the cost of replenishing working capital for the construction process, which will inevitably be included in the price per square meter of housing and paid by the consumer (population). At the same time, banks become the main controllers and beneficiaries of the project financing. The model developed and tested by the authors will allow construction organizations to overcome the first difficulties of project financing application and competently and consistently make a choice of a strategy for offering housing to buyers, taking into account the variability of the economic parameters of all parties

GREEN TECHNOLOGIES OF URAL INDUSTRIAL COMPANIES: ON THE WAY TO SUSTAINABLE DEVELOPMENT

The article shows the main provisions on the "green" economy and "green" technologies. The review of the largest industrial units of the Ural Federal District is carried out, as well as data on the costs of enterprises aimed at reducing the harmful effects of production. As a result of the study, it is concluded about the effectiveness of the introduction of "green" technologies in production, as well as the benefits of the transition to a "green" economy both for one district and for the whole country.В статье показаны основные положения о «зеленой» экономике и «зеленых» технологиях. Проведен обзор крупнейших промышленных единиц Уральского Федерального Округа, а также представлены данные по расходам предприятий, направленных на снижение вредного воздействия от производств. В результате исследования делается вывод об эффективности внедрения эко-технологий в производство, а также о пользе перехода к «зеленой» экономике как для одного округа, так и для всей страны

METHODS FOR SENTINEL LYMPH NODE DETECTION IN PATIENTS WITH BREAST CANCER

Objective: to provide various methods for sentinel lymph node detection considering their advantages and disadvantages.Material and Methods. The search of the relevant articles published in Pubmed, MedLine, RINTs, etc. database was conducted. 49 publications from 1970 to 2018 were analyzed.Results. Currently, sentinel lymph node biopsy (SLN biopsy) has become a worthy alternative to traditional lymphatic surgery for early breast cancer. SLN biopsy significantly decreases the number of postoperative complications caused by lymphadenectomy and improves the quality of life of cancer patients. So far, a large number of SLN detection techniques have accumulated. Each of these techniques has its own advantages and disadvantages.Conclusion. Despite a large number of SLN detection methods, the question of the optimal technique is currently debatable