2 research outputs found
Kawasaki disease is more prevalent in rural areas of Catalonia (Spain)
INTRODUCTION: Kawasaki disease (KD) is an acute self-limited
systemic vasculitis relatively common in childhood. The etiology
of KD is still unknown, although clinical, laboratory and
epidemiological features suggest an infectious origin or
trigger. Differences on incidence between countries have been
related to specific genetic factors, ethnicity, country of birth
and some other sociocultural and environmental factors. We
present a population-based study on incidence of KD in Catalonia
(Spain), focusing on differences between patients in rural and
non-rural areas of the region. METHODS: Observational
population-based study including all Pediatric Units in Catalan
hospitals, between 2004 and 2014. A 12-month (March 2013-March
2014) prospective collection of new cases of KD was carried out
to determine the incidence of KD. The rest of the data was
retrieved retrospectively. RESULTS: Data from 399 patients over
the 10-year study period was analyzed. Among the total KD
patients, 353 (88.5%) lived in non-rural areas and 46 (11.5%) in
rural areas. It was found that there is a significant difference
(P<.001) between the percentage of rural population observed
in patients with KD (11.5%), and the expected 5% of the Catalan
population. CONCLUSION: This is the first population-based study
showing significant differences on KD incidence rates between
rural and non-rural areas
Kawasaki disease is more prevalent in rural areas of Catalonia (Spain)
INTRODUCTION: Kawasaki disease (KD) is an acute self-limited
systemic vasculitis relatively common in childhood. The etiology
of KD is still unknown, although clinical, laboratory and
epidemiological features suggest an infectious origin or
trigger. Differences on incidence between countries have been
related to specific genetic factors, ethnicity, country of birth
and some other sociocultural and environmental factors. We
present a population-based study on incidence of KD in Catalonia
(Spain), focusing on differences between patients in rural and
non-rural areas of the region. METHODS: Observational
population-based study including all Pediatric Units in Catalan
hospitals, between 2004 and 2014. A 12-month (March 2013-March
2014) prospective collection of new cases of KD was carried out
to determine the incidence of KD. The rest of the data was
retrieved retrospectively. RESULTS: Data from 399 patients over
the 10-year study period was analyzed. Among the total KD
patients, 353 (88.5%) lived in non-rural areas and 46 (11.5%) in
rural areas. It was found that there is a significant difference
(P<.001) between the percentage of rural population observed
in patients with KD (11.5%), and the expected 5% of the Catalan
population. CONCLUSION: This is the first population-based study
showing significant differences on KD incidence rates between
rural and non-rural areas