13 research outputs found

    Linguistic and Extralinguistic Aspects of Study of Modern Russian Rap Texts

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    An overview of modern domestic and foreign linguistic studies of rap texts is presented. The features of rap as part of the global hip-hop culture are considered. The proof is given that rap text as a component of rap culture is the dominant of the subculture, and domestic rap is an authentic phenomenon. It is shown that over the past twenty years, the subject of research in the field of studying Russian-language rap texts has become more diverse. The main linguistic aspects of the study of rap texts (lexicon of rappers, slangisms, intertextual inclusions, gender characteristics, paronymic attraction) are revealed. The novelty of the research is seen in the fact that the status of rap text as an object of linguistic research has been clarified, and guidelines have been created for further practical analysis of this type of text. For the first time, a number of works by foreign scientists that have not previously been presented in the domestic scientific space and which define new perspectives in the study of the Russian-language rap text are highlighted. Particular attention is paid to debatable issues about the status of rap text, its genre features. The authors of the article argue that the leading mechanism of text generation in Russian-language rap is paronymic attraction, which gives reason to consider rap text as a literary text

    Taxis in Text Structure (Based on B. Pasternak’s Letters from Tula)

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    Поступила в редакцию: 26.11.2020. Принята к печати: 14.03.2021.Submitted: 26.11.2020. Accepted: 14.03.2021.Статья посвящена проблеме анализа функционально-семантической категории таксиса как текстовой категории в структуре целостного текста монтажного типа. Материалом исследования стал рассказ Б. Пастернака «Письма из Тулы» (1918), выбор которого обусловлен спецификой текстовой структуры. В тексте монтажного типа функционально-семантическая категория таксиса отражает авторское представление о временнόй сопряженности действий в рамках целостного временнόго периода, темпоральной рамки, границы которой определяются перцептором. Основными методами лингвистического анализа стали описательно-аналитический, интерпретативный. В структуре текста монтажного типа становится очевидной связь категории таксиса с идеей семантической множественности ситуаций. Их погруженность в единую темпоральную рамку, а также система используемых синтаксических средств и связей позволяет снять изолированность и преодолеть симультанность текста. Особое внимание уделяется системе синтаксических средств реализации функционально-семантической категории таксиса. Такой подход позволяет выявить особенности пространственно-временной организации текста, обнаружить принципы сочетаемости компонентов текста и их обусловленность. Выражаемые системой грамматических средств актуальные элементы таксисной семантики отражают сопряженность действий и интенциональность таксисных значений. В структуре текста таксисные отношения возникают между соположенными, не обусловленными логическими связями фрагментами текста; дистантно расположенными фрагментами, связанными лишь рамками общего временнόго отрезка. Преобладающим типом отношений становится одновременность. Система грамматических средств организации таксиса: аспектуальная семантика глаголов и глагольных форм, параллелизм синтаксических структур, различные типы синтаксических повторов, — становится фактором, позволяющим объединить в тексте параллельно развивающиеся тематические линии, разные способы повествования, показать процесс перцептивной деятельности, сосредоточив читательское внимание на нескольких одновременно осмысляемых событиях как интегрированном фрагменте действительности и стабилизировать пространство монтажного текста. Связь таксиса с точкой зрения субъекта и конструируемой им ситуацией упорядочивает связи между субъективным и объективным, образным и логическим, усиливая интенциональность таксисной семантики, одной из функций которой становится организация читательской стратегии.This article is devoted to the problem of analysing the taxis as a text category in the structure of a consistent montage text. The research refers to Letters from Tula (1918), a novel by B. Pasternak. The choice of the text is due to the specifics of its structure. In a montage text, the functional-semantic category of the taxis reflects the author’s idea of the temporal correlation of actions within the framework of an integral period, a temporal frame. Its boundaries are determined by the perceiver. The main methods of linguistic analysis in the article are the descriptive, analytical, and interpretive. The connection between the taxis category and the idea of a semantic plurality of situations appears in the structure of the montage text. Their immersion in a single temporal frame and the system of syntactic means and connections allows them to overcome the simultaneity of the text. Special attention is paid to the system of syntactic means of taxis implementation. This approach makes it possible to reveal the features of the spatio-temporal organisation of the text and discover the principles of compatibility of the components of the text, and their conditionality. The system of grammatical means reflects the conjugation of actions and the intentionality of taxis meanings. In the structure of the text, taxis relations arise between juxtaposed and distantly located fragments of the text connected only by the framework of a common period. Simultaneity becomes the predominant type of the relationship. The system of grammatical means of taxis organisation made up by the unity of aspectual semantics, the parallelism of syntactic structures, and various types of syntactic repetitions becomes a factor that makes it possible to combine parallel developing thematic lines and different ways of narration in the text to show the process of perceptual activity, drawing the reader’s attention to several simultaneously comprehended events as an integrated fragment of reality and stabilising the space of the montage text. The connection between the taxis and the subject’s point of view organises the connections between the subjective and the objective, the figurative and the logical and strengthens the intentionality of taxis semantics, one of whose functions is the organisation of the reading strategy

    Carfilzomib and dexamethasone versus bortezomib and dexamethasone for patients with relapsed or refractory multiple myeloma (ENDEAVOR): And randomised, phase 3, open-label, multicentre study

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    Background: Bortezomib with dexamethasone is a standard treatment option for relapsed or refractory multiple myeloma. Carfilzomib with dexamethasone has shown promising activity in patients in this disease setting. The aim of this study was to compare the combination of carfilzomib and dexamethasone with bortezomib and dexamethasone in patients with relapsed or refractory multiple myeloma. Methods: In this randomised, phase 3, open-label, multicentre study, patients with relapsed or refractory multiple myeloma who had one to three previous treatments were randomly assigned (1:1) using a blocked randomisation scheme (block size of four) to receive carfilzomib with dexamethasone (carfilzomib group) or bortezomib with dexamethasone (bortezomib group). Randomisation was stratified by previous proteasome inhibitor therapy, previous lines of treatment, International Staging System stage, and planned route of bortezomib administration if randomly assigned to bortezomib with dexamethasone. Patients received treatment until progression with carfilzomib (20 mg/m2 on days 1 and 2 of cycle 1; 56 mg/m2 thereafter; 30 min intravenous infusion) and dexamethasone (20 mg oral or intravenous infusion) or bortezomib (1·3 mg/m2; intravenous bolus or subcutaneous injection) and dexamethasone (20 mg oral or intravenous infusion). The primary endpoint was progression-free survival in the intention-to-treat population. All participants who received at least one dose of study drug were included in the safety analyses. The study is ongoing but not enrolling participants; results for the interim analysis of the primary endpoint are presented. The trial is registered at ClinicalTrials.gov, number NCT01568866. Findings: Between June 20, 2012, and June 30, 2014, 929 patients were randomly assigned (464 to the carfilzomib group; 465 to the bortezomib group). Median follow-up was 11·9 months (IQR 9·3-16·1) in the carfilzomib group and 11·1 months (8·2-14·3) in the bortezomib group. Median progression-free survival was 18·7 months (95% CI 15·6-not estimable) in the carfilzomib group versus 9·4 months (8·4-10·4) in the bortezomib group at a preplanned interim analysis (hazard ratio [HR] 0·53 [95% CI 0·44-0·65]; p<0·0001). On-study death due to adverse events occurred in 18 (4%) of 464 patients in the carfilzomib group and in 16 (3%) of 465 patients in the bortezomib group. Serious adverse events were reported in 224 (48%) of 463 patients in the carfilzomib group and in 162 (36%) of 456 patients in the bortezomib group. The most frequent grade 3 or higher adverse events were anaemia (67 [14%] of 463 patients in the carfilzomib group vs 45 [10%] of 456 patients in the bortezomib group), hypertension (41 [9%] vs 12 [3%]), thrombocytopenia (39 [8%] vs 43 [9%]), and pneumonia (32 [7%] vs 36 [8%]). Interpretation: For patients with relapsed or refractory multiple myeloma, carfilzomib with dexamethasone could be considered in cases in which bortezomib with dexamethasone is a potential treatment option. Funding: Onyx Pharmaceuticals, Inc., an Amgen subsidiary

    NECESSITY OF PROFESSIONAL PEDAGOGICAL COMPETENCE FOR NURSING CARE SPECIALISTS

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    Recently, there is a rising research interest in the issue of professional competence as a whole and of nursing care specialists` competence involved in medical education and social work. That is why professional competence transforms into a basic element of the university medical education under these conditions. It incorporates not only knowledge in the field of medicine but also formation of a variety of communicative skills ensuring a qualitative care to the patients. Contemporary medical staff should be capable of solving the health problems based on ethical work standards. This is due to the fact that nursing care specialists are responsible for the maintenance, promotion, rehabilitation and provision of care for rehabilitation and treatment as well as for education of the patients and their relatives

    Designing trainer’s manual for the ISG for competence project

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    The two-volume set LNCS 10896 and 10897 constitutes the refereed proceedings of the 16th International Conference on Computers Helping People with Special Needs, ICCHP 2018, held in Linz, Austria, in July 2018. The 101 revised full papers and 78 short papers presented were carefully reviewed and selected from 356 submissions. The papers are organized in the following topical sections: Web accessibility in the connected world; accessibility and usability of mobile platforms for people with disabilities and elderly persons: design, development and engineering; accessible system/information/document design; accessible e-learning - e-learning for accessibility/AT; personalized access to TV, film, theatre, and music; digital games accessibility; accessibility and usability of self-service terminals, technologies and systems; universal learning design; motor and mobility disabilities: AT, HCI, care; empowerment of people with cognitive disabilities using digital technologies; augmented and alternative communication (AAC), supported speech; Art Karshmer lectures in access to mathematics, science and engineering; environmental sensing technologies for visual impairment; 3D printing in the domain of assistive technologies (AT) and do it yourselves (DIY) AT; tactile graphics and models for blind people and recognition of shapes by touch; access to artworks and its mediation by and for visually impaired people; digital navigation for people with visual impairments; low vision and blindness: human computer interaction; future perspectives for aging well: AAL tools, products, devices; mobile healthcare and m-health apps for people with disabilities; and service and information provision

    Hemolytic Anemia as a Presenting Feature of Wilson’s Disease: A Case Report

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    Wilson’s disease is a rare inherited disorder of copper metabolism causing severe damage to vital organs. Liver and brain disorders are the main manifestations. Severe hemolytic anemia is an unusual complication of Wilson’s disease. We present a case who developed spherocytic acute hemolytic anemia (Coomb’s negative) as the initial manifestation of Wilson’s disease. On examination Kayser- Fleischer ring was found. Laboratory data supported a diagnosis of Wilson’s disease
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