A função de controle nos sistemas integrados de manufatura

Faz-se uma proposição de vários conceitos atinentes ao gerenciamento da produção, muitos dos quais são válidos também para os Sistemas de Manufatura Convencional, mas que estão aqui colocados dentro do contexto dos Sistemas Integrados de Manufatura (SIMs), que são os sistemas desenvolvidos sob a filosofia de fabricação CIM ('Computer Integrated Manufacturing = Manufatura Integrada por Computador). Mostra-se que a integração depende basicamente da função controle.<br>Manufacturing integration is reviewed and various concepts and definitions founded in literature are presented for conventional and automated manufacturing systems. The survey emphasizes information system management and control importance in order to improve manufacturing functions integration

Genetics of physical wood properties and early growth in a tropical pine hybrid

Quantitative trait locus (QTL) detection was carried out for physical wood properties and early growth traits in an interspecific hybrid between Pinus elliottii var. elliottii Engelm. and Pinus caribaea var. hondurensis (Senecl) Barr. et Golf. A pseudo-testcross QTL detection strategy was used to identify genome regions that influenced wood density, secondary growth, and dry wood mass index on each genetic map for the parents of a single F, family (n = 133). Traits were measured for annual ring and earlywood and latewood components and were based on both individual and average ring values from 1996 to 1999. A total of 12 significant putative QTLs were identified that clustered into four genomic regions in the P. elliottii var. elliottii parent and a single region in the P. caribaea var. hondurensis parent. The P. elliottii var. elliottii parent largely contributed putative QTLs for diameter growth and wood density, whereas the P caribaea var. hondurensis parent contributed a putative QTL for earlywood formed in 1997. Putative QTLs that influenced density and ring width did not colocate, suggesting independent inheritance of these characters. This was consistent with the lack of genetic correlation between wood density and diameter growth observed in quantitative studies in hybrid pines

Pines

Pinus is the most important genus within the Family Pinaceae and also within the gymnosperms by the number of species (109 species recognized by Farjon 2001) and by its contribution to forest ecosystems. All pine species are evergreen trees or shrubs. They are widely distributed in the northern hemisphere, from tropical areas to northern areas in America and Eurasia. Their natural range reaches the equator only in Southeast Asia. In Africa, natural occurrences are confined to the Mediterranean basin. Pines grow at various elevations from sea level (not usual in tropical areas) to highlands. Two main regions of diversity are recorded, the most important one in Central America (43 species found in Mexico) and a secondary one in China. Some species have a very wide natural range (e.g., P. ponderosa, P. sylvestris). Pines are adapted to a wide range of ecological conditions: from tropical (e.g., P. merkusii, P. kesiya, P. tropicalis), temperate (e.g., P. pungens, P. thunbergii), and subalpine (e.g., P. albicaulis, P. cembra) to boreal (e.g., P. pumila) climates (Richardson and Rundel 1998, Burdon 2002). They can grow in quite pure stands or in mixed forest with other conifers or broadleaved trees. Some species are especially adapted to forest fires, e.g., P. banksiana, in which fire is virtually essential for cone opening and seed dispersal. They can grow in arid conditions, on alluvial plain soils, on sandy soils, on rocky soils, or on marsh soils. Trees of some species can have a very long life as in P. longaeva (more than 3,000 years)

Prevention and Attenuation of Covid-19 with the BNT162b2 and mRNA-1273 Vaccines

BACKGROUND Information is limited regarding the effectiveness of the two-dose messenger RNA (mRNA) vaccines BNT162b2 (Pfizer-BioNTech) and mRNA-1273 (Moderna) in preventing infection with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and in attenuating coronavirus disease 2019 (Covid-19) when administered in realworld conditions. METHODS We conducted a prospective cohort study involving 3975 health care personnel, first responders, and other essential and frontline workers. From December 14, 2020, to April 10, 2021, the participants completed weekly SARS-CoV-2 testing by providing mid-turbinate nasal swabs for qualitative and quantitative reverse-transcriptase-polymerase-chain-reaction (RT-PCR) analysis. The formula for calculating vaccine effectiveness was 100% × (1 - hazard ratio for SARS-CoV-2 infection in vaccinated vs. unvaccinated participants), with adjustments for the propensity to be vaccinated, study site, occupation, and local viral circulation. RESULTS SARS-CoV-2 was detected in 204 participants (5%), of whom 5 were fully vaccinated (≥14 days after dose 2), 11 partially vaccinated (=14 days after dose 1 and <14 days after dose 2), and 156 unvaccinated; the 32 participants with indeterminate vaccination status (<14 days after dose 1) were excluded. Adjusted vaccine effectiveness was 91% (95% confidence interval [CI], 76 to 97) with full vaccination and 81% (95% CI, 64 to 90) with partial vaccination. Among participants with SARS-CoV-2 infection, the mean viral RNA load was 40% lower (95% CI, 16 to 57) in partially or fully vaccinated participants than in unvaccinated participants. In addition, the risk of febrile symptoms was 58% lower (relative risk, 0.42; 95% CI, 0.18 to 0.98) and the duration of illness was shorter, with 2.3 fewer days spent sick in bed (95% CI, 0.8 to 3.7). CONCLUSIONS Authorized mRNA vaccines were highly effective among working-age adults in preventing SARS-CoV-2 infection when administered in real-world conditions, and the vaccines attenuated the viral RNA load, risk of febrile symptoms, and duration of illness among those who had breakthrough infection despite vaccination. (Funded by the National Center for Immunization and Respiratory Diseases and the Centers for Disease Control and Prevention.) Copyright © 2021 Massachusetts Medical Society.No embargo COVID-19This item from the UA Faculty Publications collection is made available by the University of Arizona with support from the University of Arizona Libraries. If you have questions, please contact us at [email protected]