One or many project offices in educational organization of tertiary education: advantages and disadvantages

The article is devoted to the creating and management expediency of several project offices in an educational organization of tertiary education (hereinafter – OTE). The topic relevance is due to the growing number and types of ongoing projects that require proper organization and management and, consequently, governance of project management offices. The article presents the features of educational projects and the role of the project management office in the OTE system. The main types of project management offices at universities and their functions and tasks are described. Common elements of successful project management offices from around the world are highlighted based on a global study conducted by the Project Management Institute (PMI) together with PricewaterhouseCoopers (PwC) in 2021. The advantages and disadvantages of creating a single system of several project offices of different orientation and a single project management office at the university are discussed. Based on the information from the scientific literature and the conducted research, the authors conclude that in order to use all the advantages of the project office in full, it is necessary to create one project office in OTE. However, the authors also claim the need for further research to assess the feasibility of the practical implementation of their proposed solution

Role of membrane lipids in the regulation of erythrocytic oxygen-transport function in cardiovascular diseases

The composition and condition of membrane lipids, the morphology of erythrocytes, and hemoglobin distribution were explored with the help of laser interference microscopy (LIM) and Raman spectroscopy. It is shown that patients with cardiovascular diseases (CVD) have significant changes in the composition of their phospholipids and the fatty acids of membrane lipids. Furthermore, the microviscosity of the membranes and morphology of the erythrocytes are altered causing disordered oxygen transport by hemoglobin. Basic therapy carried out with the use of antiaggregants, statins, antianginals, beta-blockers, and calcium antagonists does not help to recover themorphofunctional properties of erythrocytes. Based on the results the authors assume that, for the relief of the ischemic crisis and further therapeutic treatment, it is necessary to include, in addition to cardiovascular disease medicines, medication that increases the ability of erythrocytes’ hemoglobin to transport oxygen to the tissues. We assume that the use of LIM and Raman spectroscopy is advisable for early diagnosis of changes in the structure and functional state of erythrocytes when cardiovascular diseases develop

Magnetospheric convection from Cluster EDI measurements compared with the ground-based ionospheric convection model IZMEM

Cluster/EDI electron drift observations above the Northern and Southern polar cap areas for more than seven and a half years (2001–2008) have been used to derive a statistical model of the high-latitude electric potential distribution for summer conditions. Based on potential pattern for different orientations of the interplanetary magnetic field (IMF) in the GSM y-z-plane, basic convection pattern (BCP) were derived, that represent the main characteristics of the electric potential distribution in dependence on the IMF. The BCPs comprise the IMF-independent potential distribution as well as patterns, which describe the dependence on positive and negative IMF<I>B<sub>z</sub></I> and IMF<I>B<sub>y</sub></I> variations. The full set of BCPs allows to describe the spatial and temporal variation of the high-latitude electric potential (ionospheric convection) for any solar wind IMF condition near the Earth's magnetopause within reasonable ranges. The comparison of the Cluster/EDI model with the IZMEM ionospheric convection model, which was derived from ground-based magnetometer observations, shows a good agreement of the basic patterns and its variation with the IMF. According to the statistical models, there is a two-cell antisunward convection within the polar cap for northward IMF<I>B<sub>z</sub></I>+≤2 nT, while for increasing northward IMF<I>B<sub>z</sub></I>+ there appears a region of sunward convection within the high-latitude daytime sector, which assumes the form of two additional cells with sunward convection between them for IMF<I>B<sub>z</sub></I>+≈4–5 nT. This results in a four-cell convection pattern of the high-latitude convection. In dependence of the ±IMF<I>B<sub>y</sub></I> contribution during sufficiently strong northward IMF<I>B<sub>z</sub></I> conditions, a transformation to three-cell convection patterns takes place

The roles of vitamin D in the prevention and the therapy of male infertility

The results of fundamental and clinical studies show the importance of providing males with vitamin D in order to (1) assist the formation of the testicles, (2) maintain the steroid-synthesizing and other functions of the testicles, (3) maintain the functioning of the spermatozoa and, in general, maintain the male fertility

2-aminoaethanesulfonic acid compounds possess protective property in reperfusion-induced heart jnjury

The study aim was to explore pharmacological effects of 2-aminoaethansulfonic acid compounds in reperfusion-induced heart injury. The study was performed on rats and dogs of both sexes, isolated rats’ hearts. Two compounds of 2-aminoethanesulfonic acid, magnesium-containing (LBK-527) and phenylacetamide-containing (LKhT-317) were investigate

Characteristics of the electrojet during intense magnetic disturbances

Hall current variations in different time sectors during six magnetic storms from the summer seasons in 2003 and 2005 (Ritter, 2018) are examined, namely three storms in the day–night meridional sector and three storms in the dawn–dusk sector. The sequence of the phenomena, their structure and positions, and the strength of the polar (PE) and the auroral (AE) Hall electrojets were investigated using scalar magnetic field measurements obtained from the CHAllenging Minisatellite Payload (CHAMP) satellite in accordance with the study of Ritter et al. (2004a). We analyzed the correlations of the PE and AE as well as the obtained regression relations of the magnetic latitude MLat and the electrojet current intensity I with auroral and ring current activity, the interplanetary magnetic field, and the Newell et al. (2007) coupling function for the state of the solar wind. The following typical characteristics of the electrojets were revealed:The PE appears in the daytime sector at MLat&thinsp; ∼ 80°–73°, with a westward or an eastward direction depending on the interplanetary magnetic field (IMF) By component (By&thinsp; &lt; &thinsp;0&thinsp;nT or By&thinsp; &gt; &thinsp;0&thinsp;nT). Changes in the current flow direction in the PE can occur repeatedly during the storm, but only due to changes in the IMF By orientation. The PE increases with the intensity of the IMF By component from I ∼ 0.4&thinsp;A&thinsp;m−1 for By ∼ 0&thinsp;nT up to I ∼ 1.0&thinsp;A&thinsp;m−1 for By ∼ 23&thinsp;nT. The MLat position of the PE does not depend on the direction and intensity of the By component.There is no connection between MLat and I in the PE and the symmetric part of the magnetospheric ring current (index SymH). There is a correlation between I in the PE and the AsyH index, but only a very weak interconnection of this index with the MLat of the PE.Substorms occurring before the storm's main phase are accompanied by the appearance of an eastward electrojet (EE) at MLat&thinsp; ∼ 64° as well as that of a westward electrojet (WE). In the nighttime sector, a WE appears at MLat&thinsp; ∼ 64°. During the main phase both electrojets persist. The daytime EE and the nighttime WE shift toward sub-auroral latitudes of MLat&thinsp; ∼ 56° and grow in intensity up to I ∼ 1.5&thinsp;A&thinsp;m−1. The WE is then located about 6° closer to the pole than the EE during evening hours and about 2°–3° closer during daytime hours.</p