2,732 research outputs found

    A geometric method for model reduction of biochemical networks with polynomial rate functions

    No full text

    The temperature dependence of the isothermal bulk modulus at 1 bar pressure

    Get PDF
    It is well established that the product of the volume coefficient of thermal expansion and the bulk modulus is nearly constant at temperatures higher than the Debye temperature. Using this approximation allows predicting the values of the bulk modulus. The derived analytical solution for the temperature dependence of the isothermal bulk modulus has been applied to ten substances. The good correlations to the experiments indicate that the expression may be useful for substances for which bulk modulus data are lacking

    Multi-rendezvous Spacecraft Trajectory Optimization with Beam P-ACO

    Full text link
    The design of spacecraft trajectories for missions visiting multiple celestial bodies is here framed as a multi-objective bilevel optimization problem. A comparative study is performed to assess the performance of different Beam Search algorithms at tackling the combinatorial problem of finding the ideal sequence of bodies. Special focus is placed on the development of a new hybridization between Beam Search and the Population-based Ant Colony Optimization algorithm. An experimental evaluation shows all algorithms achieving exceptional performance on a hard benchmark problem. It is found that a properly tuned deterministic Beam Search always outperforms the remaining variants. Beam P-ACO, however, demonstrates lower parameter sensitivity, while offering superior worst-case performance. Being an anytime algorithm, it is then found to be the preferable choice for certain practical applications.Comment: Code available at https://github.com/lfsimoes/beam_paco__gtoc

    Use of the two-level contact and distributive devices in reactors of trial installation productions of methyl air of fat acids

    Get PDF
    Justified by the value of dispersion and uniform distribution of flow in the apparatus for a liquidliquid interactions. Showing the relevance of phase dispersion and distribution of flows in the column reactor plants for fatty acid methyl esters. The design and principle of operation of the contact and switchgear for the esterification reactor, neutralization and washing of the plant. Based on the experience of the plant confirmed efficiency and effectiveness of the device, as well as recommendations for its wider use

    Integrative Modeling of Electrical Properties of Pacemaker Cardiac Cells

    Get PDF
    This work represents modeling of electrical properties of pacemaker (sinus) cardiac cells. Special attention is paid to electrical potential arising from transmembrane current of Na{+}, K{+} and Ca{2+} ions. This potential is calculated using the NaCaX model. In this respect, molar concentration of ions in the intercellular space which is calculated on the basis of the GENTEX model is essential. Combined use of two different models allows referring this approach to integrative modeling
    corecore