1,909 research outputs found
Some Effects of Methyl Green on Expression of Damage Induced in G1 Xenopus Cells by Ultraviolet Light
A design handbook for phase change thermal control and energy storage devices
Comprehensive survey is given of the thermal aspects of phase change material devices. Fundamental mechanisms of heat transfer within the phase change device are discussed. Performance in zero-g and one-g fields are examined as it relates to such a device. Computer models for phase change materials, with metal fillers, undergoing conductive and convective processes are detailed. Using these models, extensive parametric data are presented for a hypothetical configuration with a rectangular phase change housing, using straight fins as the filler, and paraffin as the phase change material. These data are generated over a range of realistic sizes, material properties, and thermal boundary conditions. A number of illustrative examples are given to demonstrate use of the parametric data. Also, a complete listing of phase change material property data are reproduced herein as an aid to the reader
Behavioral self-management in organizational settings
The intent of this study was to examine the effectiveness of behavioral self-management for mid-level managers in a variety of organizational settings. Behavioral self-management combines some of the current techniques found in behavioral psychology and management research. The present approach uses behavioral self-control and certain aspects of time management in a four-term contingency analysis (SOBC) to systematically control work-related problems that result in less than optimal performance. Eight individuals who occupied middle-management positions participated in the study. The behavioral self-management approach was used to successfully manage a total of about 20 out of 23 target behaviors associated with on-the-job performance. Each manager selected, modified, and evaluated each of their chosen problem events. Seven participants worked on three target behaviors each and one participant worked on two. Results were highly favorable, indicating that the approach can be successfully used by middle-managers in various settings to increase the effectiveness of their own performance. It was concluded that the possibility of success with several types of work-related problems is high, provided the manager is committed to following the program and that the problems have been adequately identified. An exit interview revealed that seven of the eight managers were convinced of the program\u27s effectiveness and usefulness in managing the target behaviors. Ratings of each manager\u27s graphed results were made by nine individuals who were knowledgeable in the techniques of behavior analysis. Their ratings, which were very similar to the exit interview results, suggest a medium to considerable amount of behavior change on almost all target behaviors
Corporation Law: Delaware Supreme Court Exercises Its Own Business Judgment
Zapata Corporation v. Maldonado, 430 A.2d 779 (Del. 1981).
The derivative suit is a device by which minority shareholders can enforce corporate rights that are violated by corporate management. The business judgment rule is the defense mechanism asserted by the board of directors to compel dismissal of the shareholder\u27s suit. The continued vitality of derivative suits has been seriously threatened by state and federal decisions which have consistently upheld reliance on the business judgment rule as a grounds for disinterested directors to dismiss derivative actions they deem detrimental to the corporation.
Provided the directors do not stand in a dual relation creating the risk of biased decisions, the traditional application of the rule bars judicial inquiry into actions of directors taken in good faith and in honest pursuit of the legitimate purposes of the corporation.
This long line of precedent was broken in May, 1981, with the Supreme Court of Delaware decision Zapata Corp. v. Maldonado. In this decision, the Delaware court created a new two prong test to be employed when deciding whether directors\u27 dismissal of a derivative suit is proper. The change of precedent occurs in the test\u27s second step, which calls upon the trial court to exercise its own business judgment to decide whether the board\u27s motion to dismiss a shareholder\u27s derivative suit should be granted. This means, of course, that instances could arise where a committee can establish its independence and sound basis for its good faith decisions and still have the corporation\u27s motion denied. This note outlines the reasoning behind the Zapata court\u27s new approach, and discusses its potential impact on future appeals determining the validity of an independent board\u27s decision not to sue
Thermoregulatory responses of athletes with a spinal cord injury during rest and exercise
Following on from Rio de Janeiro 2016, the Tokyo 2020 Paralympic Games will present a unique challenge for athletes, needing to prepare and adapt to the potential challenging environmental conditions of 20-27°C and ~73% relative humidity. It is well known that during exercise in hot and/or humid climates, able-bodied athletes experience an increase in thermal strain and a reduction in performance compared to cooler/drier conditions. Yet these conditions prove even more problematic for athletes, who as a consequence of their impairment have a dysfunctional thermoregulatory system, such as athletes with a spinal cord injury (SCI). To date, the thermoregulatory responses of athletes with an SCI have been an under-studied area of research. To gain a greater understanding of how heat balance is altered in individuals with an SCI and the thermoregulatory consequences as a result, studies need to first be conducted at rest, removing the additional metabolic heat production from exercise.
Although a large majority of athletes with an SCI compete indoors in wheelchair court sports (e.g. wheelchair basketball and rugby), exercising even in these climate-controlled environments has been shown to place these athletes under considerable thermal strain. In light of this, it is remarkable that existing research on the thermoregulatory responses of athletes with an SCI during exercise is scarce, especially studies encompassing real-world sporting environments. Athletes with high level lesions (tetraplegia, TP) are a particularly under-studied population group shown to have a greater thermoregulatory impairment than individuals with low level lesions (paraplegia, PA) during continuous exercise. Thus the aim of this thesis was to investigate the thermoregulatory responses of athletes with an SCI at rest and during real-world sporting scenarios, with specific focus on athletes with TP.
Study 1 aimed to determine how evaporative heat loss is altered, as a result of an SCI, compared to the able-bodied (AB), and the effect lesion level has on this response. The results provide evidence that in individuals with TP, even at rest, evaporative heat loss is not large enough to balance the heat load, when evaporation is the primary source of heat dissipation. Even though in individuals with PA Tgi increased by a smaller magnitude and they possessed a greater sweating capacity than individuals with TP, at ambient temperatures above Tsk latent heat loss is insufficient to attain heat balance, compared to the AB.
To investigate the thermoregulatory responses of athletes with an SCI during real-world sporting scenarios Study 2 examined athletes with TP compared to athletes with PA during 60 min of intermittent sprint wheelchair exercise on a wheelchair ergometer. The study was conducted in conditions representative of an indoor playing environment for wheelchair rugby and basketball (~21°C, 40% relative humidity). Results demonstrated that, despite similar external work, athletes with TP were under greater thermal strain than athletes with PA.
Study 3 s novel approach investigated both physiological responses and activity profiles of wheelchair rugby players during competitive match play. Despite players with TP covering 17% less distance and pushing on average 10% slower, they were under a greater amount of thermal strain than players with non-spinal related physical impairments (NON-SCI). Furthermore, this study demonstrated that players with TP that had a larger body mass, larger lean mass, covered a greater relative distance and/or were a higher point player had a greater end Tgi. These data provide an insight for coaches and support staff regarding which players may need greater attention in regards to cooling strategies or breaks in play.
The effectiveness of cooling practices currently employed by athletes with TP has not been previously investigated. Study 4 determined the effectiveness of pre-cooling, using an ice vest alone and in combination with water sprays between quarters, at attenuating thermal strain in athletes with TP. Using the activity profile data from Study 3, an intermittent sprint protocol, conducted on a wheelchair ergometer, was used to represent a wheelchair rugby match. The combination of cooling methods lowered Tgi and Tsk to a greater extent than pre-cooling only, despite neither cooling condition having a positive or negative effect on performance. Unexpectedly, the pre-cooling only condition lowered Tgi, compared to no cooling, throughout the subsequent exercise protocol, even though the reduction in Tsk was not long lasting.
This thesis provides comprehensive evidence that athletes with TP experience heightened thermal strain during both rest and real-world sporting scenarios compared to the AB, athletes with PA, and within the sport of wheelchair rugby. Athletes with TP should employ practices, such as appropriate cooling methods or alter playing tactics to reduce thermal strain and the likelihood of attaining a heat related injury
Rate dependent shear bands in a shear transformation zone model of amorphous solids
We use Shear Transformation Zone (STZ) theory to develop a deformation map
for amorphous solids as a function of the imposed shear rate and initial
material preparation. The STZ formulation incorporates recent simulation
results [Haxton and Liu, PRL 99 195701 (2007)] showing that the steady state
effective temperature is rate dependent. The resulting model predicts a wide
range of deformation behavior as a function of the initial conditions,
including homogeneous deformation, broad shear bands, extremely thin shear
bands, and the onset of material failure. In particular, the STZ model predicts
homogeneous deformation for shorter quench times and lower strain rates, and
inhomogeneous deformation for longer quench times and higher strain rates. The
location of the transition between homogeneous and inhomogeneous flow on the
deformation map is determined in part by the steady state effective
temperature, which is likely material dependent. This model also suggests that
material failure occurs due to a runaway feedback between shear heating and the
local disorder, and provides an explanation for the thickness of shear bands
near the onset of material failure. We find that this model, which resolves
dynamics within a sheared material interface, predicts that the stress weakens
with strain much more rapidly than a similar model which uses a single state
variable to specify internal dynamics on the interface.Comment: 10 pages, 13 figures, corrected typos, added section on rate
strengthening vs. rate weakening material
Spontaneous thermal runaway as an ultimate failure mechanism of materials
The first theoretical estimate of the shear strength of a perfect crystal was
given by Frenkel [Z. Phys. 37, 572 (1926)]. He assumed that as slip occurred,
two rigid atomic rows in the crystal would move over each other along a slip
plane. Based on this simple model, Frenkel derived the ultimate shear strength
to be about one tenth of the shear modulus. Here we present a theoretical study
showing that catastrophic material failure may occur below Frenkel's ultimate
limit as a result of thermal runaway. We demonstrate that the condition for
thermal runaway to occur is controlled by only two dimensionless variables and,
based on the thermal runaway failure mechanism, we calculate the maximum shear
strength of viscoelastic materials. Moreover, during the thermal
runaway process, the magnitude of strain and temperature progressively localize
in space producing a narrow region of highly deformed material, i.e. a shear
band. We then demonstrate the relevance of this new concept for material
failure known to occur at scales ranging from nanometers to kilometers.Comment: 4 pages, 3 figures. Eq. (6) and Fig. 2a corrected; added references;
improved quality of figure
-free families in the Boolean lattice
For a family of subsets of [n]=\{1, 2, ..., n} ordered by
inclusion, and a partially ordered set P, we say that is P-free
if it does not contain a subposet isomorphic to P. Let be the
largest size of a P-free family of subsets of [n]. Let be the poset with
distinct elements a, b, c, d, a<b, c<d; i.e., the 2-dimensional Boolean
lattice. We show that where . We also prove that the largest -free
family of subsets of [n] having at most three different sizes has at most
2.20711N members.Comment: 18 pages, 2 figure
The contribution of helicopter emergency medical services in the pre-hospital care of penetrating torso injuries in a semi-rural setting
BACKGROUND: Although the merit of pre-hospital critical care teams such as Helicopter Emergency Medical Services (HEMS) has been universally recognized for patients with penetrating torso injuries who present with unstable physiology, the potential merit in patients initially presenting with stable physiology is largely undetermined. The ability to predict the required pre-hospital interventions patients may have important implications for HEMS tasking, especially when transport times to definitive care are prolonged. METHODS: We performed a retrospective cohort study of patients who sustained a penetrating torso injury and were attended by the Air Ambulance Kent Surrey Sussex (AAKSS) over a 6-year period. Primary outcome was defined as the percentage of patients with penetrating torso injuries requiring HEMS-specific interventions anytime between HEMS arrival and arrival at hospital. Secondary outcomes were the association of individual patient- and injury characteristics with the requirement for HEMS interventions. RESULTS: During the study period 363 patients met inclusion criteria. 90% of patients were male with a median age of 30 years. 99% of penetrating trauma incident occurred more than 10-min drive from a Major Trauma Centre (MTC). Presenting GCS was > 13 in 83% of patients. Significant hemodynamic- or ventilatory compromise was present in more than 25% of the patients. Traumatic cardiac arrest was present in 34 patients (9.4%), profound hypotension with SBP < 80 mmHg in 30 (8.3%) and oxygen saturations < 92% in 30 (8.3%). A total of 121 HEMS-specific interventions were performed. Although HEMS-specific interventions were associated with presenting physiology (TCA OR 1.75 [1.41–2.16], SBP < 80 mmHg (OR 1.40 [1.18–1.67] and SpO(2) < 92% (OR 1.39 [1.17–1.65], a minority of the patients presented initially with stable physiology but deteriorated on route to hospital and required HEMS interventions (n = 9, 3.3%). CONCLUSION: HEMS teams provide potentially important contribution to the pre-hospital treatment of patients with penetrating torso injuries in rural and semi-rural areas, especially when they present with unstable physiology. A certain degree of over-triage is inevitable in these patients, as it is hard to predict which patients will deteriorate on route to hospital and will need HEMS interventions. The results of this study showing a potentially predictable geographical dispersion of penetrating trauma could inform multi-agency knife crime prevention strategy
Improved fluid dynamics similarity, analysis and verification. Part 4 - Acoustic velocities in two-phase mixtures of some cryogenic fluids Final report, 29 Jun. 1965 - 28 Jun. 1968
Model calculations and graphical presentation of acoustic velocities in two-phase mixtures of some cryogenic fluid
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