929 research outputs found
The Endoscopic Management of Pain in Chronic Pancreatitis
Pain resulting from chronic pancreatitis is often debilitating and difficult to manage. Many approaches have been used to treat these patients, including narcotic analgesia, antidepressants, pancreatic enzymes, octreotide, denervation procedures, such as celiac plexus block, and various palliative, decompression, or drainage procedures. Many of these procedures can be performed endoscopically, while others require a more invasive, surgical approach. The effectiveness of these therapies is not only highly variable but also often controversial. This review will discuss the endoscopic options for pain management in patients with chronic pancreatitis and their utility in treating this difficult disease
Лечение артериальной гипертензии в преклонном возрасте: от отрицания до признания необходимости
Представлен анализ результатов клинических исследований антигипертензивной терапии у пожилых пациентов, позволяющий сделать заключение о целесообразности ее проведения даже после достижения 80−летнего возраста.The analysis of the findings of clinical research of antihypertensive therapy in elderly patients, which allowed to conclude about the necessity about the expediency of its administration even in patients over 80, is presented
The Tunka Experiment: Towards a 1-km^2 Cherenkov EAS Array in the Tunka Valley
The project of an EAS Cherenkov array in the Tunka valley/Siberia with an
area of about 1 km^2 is presented. The new array will have a ten times bigger
area than the existing Tunka-25 array and will permit a detailed study of the
cosmic ray energy spectrum and the mass composition in the energy range from
10^15 to 10^18 eV.Comment: 3 pages, 2 figures, to be published in IJMP
"Last-Mile" preparation for a potential disaster
Extreme natural events, like e.g. tsunamis or earthquakes, regularly lead to catastrophes with dramatic consequences. In recent years natural disasters caused hundreds of thousands of deaths, destruction of infrastructure, disruption of economic activity and loss of billions of dollars worth of property and thus revealed considerable deficits hindering their effective management: Needs for stakeholders, decision-makers as well as for persons concerned include systematic risk identification and evaluation, a way to assess countermeasures, awareness raising and decision support systems to be employed before, during and after crisis situations. The overall goal of this study focuses on interdisciplinary integration of various scientific disciplines to contribute to a tsunami early warning information system. In comparison to most studies our focus is on high-end geometric and thematic analysis to meet the requirements of small-scale, heterogeneous and complex coastal urban systems. Data, methods and results from engineering, remote sensing and social sciences are interlinked and provide comprehensive information for disaster risk assessment, management and reduction. In detail, we combine inundation modeling, urban morphology analysis, population assessment, socio-economic analysis of the population and evacuation modeling. The interdisciplinary results eventually lead to recommendations for mitigation strategies in the fields of spatial planning or coping capacity
Search for Sub-TeV Gamma Rays Coincident with BATSE Gamma Ray Bursts
Project GRAND is a 100m x 100m air shower array of proportional wire chambers
(PWCs). There are 64 stations each with eight 1.29 m^2 PWC planes arranged in
four orthogonal pairs placed vertically above one another to geometrically
measure the angles of charged secondaries. A steel plate above the bottom pair
of PWCs differentiates muons (which pass undeflected through the steel) from
non-penetrating particles. FLUKA Monte Carlo studies show that a TeV gamma ray
striking the atmosphere at normal incidence produces 0.23 muons which reach
ground level where their angles and identities are measured. Thus,
paradoxically, secondary muons are used as a signature for gamma ray primaries.
The data are examined for possible angular and time coincidences with eight
gamma ray bursts (GRBs) detected by BATSE. Seven of the GRBs were selected
because of their good acceptance by GRAND and high BATSE Fluence. The eighth
GRB was added due to its possible coincident detection by Milagrito. For each
of the eight candidate GRBs, the number of excess counts during the BATSE T90
time interval and within plus or minus five degrees of BATSE's direction was
obtained. The highest statistical significance reported in this paper (2.7
sigma) is for the event that was predicted to be the most likely to be observed
(GRB 971110).Comment: To be presented at the XXVIII International Cosmic Ray Conference,
Tsukuba, Japa
Tunka-Rex: the Cost-Effective Radio Extension of the Tunka Air-Shower Observatory
Tunka-Rex is the radio extension of the Tunka cosmic-ray observatory in
Siberia close to Lake Baikal. Since October 2012 Tunka-Rex measures the radio
signal of air-showers in coincidence with the non-imaging air-Cherenkov array
Tunka-133. Furthermore, this year additional antennas will go into operation
triggered by the new scintillator array Tunka-Grande measuring the secondary
electrons and muons of air showers. Tunka-Rex is a demonstrator for how
economic an antenna array can be without losing significant performance: we
have decided for simple and robust SALLA antennas, and we share the existing
DAQ running in slave mode with the PMT detectors and the scintillators,
respectively. This means that Tunka-Rex is triggered externally, and does not
need its own infrastructure and DAQ for hybrid measurements. By this, the
performance and the added value of the supplementary radio measurements can be
studied, in particular, the precision for the reconstructed energy and the
shower maximum in the energy range of approximately eV. Here
we show first results on the energy reconstruction indicating that radio
measurements can compete with air-Cherenkov measurements in precision.
Moreover, we discuss future plans for Tunka-Rex.Comment: Proceeding of UHECR 2014, Springdale, Utah, USA, accepted by JPS
Conference Proceeding
Optical polarization observations with the MASTER robotic net
We present results of optical polarization observations performed with the
MASTER robotic net for three types of objects: gamma-ray bursts, supernovae,
and blazars. For the Swift gamma-ray bursts GRB100906A, GRB110422A, GRB121011A,
polarization observations were obtained during very early stages of optical
emission. For GRB100906A it was the first prompt optical polarization
observation in the world. Photometry in polarizers is presented for Type Ia
Supernova 2012bh during 20 days, starting on March 27, 2012. We find that the
linear polarization of SN 2012bh at the early stage of the envelope expansion
was less than 3%. Polarization measurements for the blazars OC 457, 3C 454.3,
QSO B1215+303, 87GB 165943.2+395846 at single nights are presented. We infer
the degree of the linear polarization and polarization angle. The blazars OC
457 and 3C 454.3 were observed during their periods of activity. The results
show that MASTER is able to measure substantially polarized light; at the same
time it is not suitable for determining weak polarization (less than 5%) of dim
objects (fainter than 16). Polarimetric observations of the optical
emission from gamma-ray bursts and supernovae are necessary to investigate the
nature of these transient objects.Comment: 31 pages, 12 figures, 4 tables; Exposure times in Table 2 have been
correcte
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