Особенности психологического статуса больных бронхиальной астмой с алекситимией

One hundred and eighteen bronchial asthma (BA) patients were examined by means of the Toronto alexithymie scale (TAS), and a brief version of the personality multilateral investigation method (PMIM), and the Spilberg-Khanin’s anxiety scale. Among them 55.1% of the patients were recognized as alexithymie persons. Asthmatic patients with alexithymia were reliably more neurotized compared with non-alexithymic ones. The revealed peculiarities of an actual personal condition of the alexithymie bronchial asthma patients cause a necessity of including methods of psychotherapeutic correction of alexithymia to a prevention measures system.Обследовано 118 больных бронхиальной астмой (БА) с помощью Торонтской апекситимической шкалы (TAS), сокращенного варианта методики многостороннего исследования личности (СМОЛ), шкалы тревоги Спилберга-Ханина. Алекситимичными признаны 55,1% пациентов с БА. Больные БА с алекситимией имели достоверно более высокий уровень невротизации личности, чем неалекситимичные индивиды. Выявленные нами особенности актуального личностного состояния алекситимичных больных бронхиальной астмой обуславливают необходимость включения в систему профилактических мероприятий методов психотерапевтической коррекции алекситимии

Research of functional respiratory status in rehabilitation and prevention of the patients with Industrially Conditioned Chronic Bronchitis

The functional respiratory status of patients with industrially conditioned chronic bronchitis was researched. The use of reflexotherapy and magnetotherapy in rehabilitations programs lead to prevention of chronic bronchitis

Clinical and immunological analysis of the effectiveness of local application of vitamin D₃ in experimental colitis

The pathogenesis of inflammatory bowel diseases has not been fully studied, and the therapies used have side effects that limit their use.The purpose of this study is to conduct a clinical and immunological analysis of the effectiveness of vitamin D3 in the original rectal suppositories in experimental colitis (EC).EC was modeled with oxazolone. Original suppositories with vitamin D3 in group 3 and 5-ASA in group 4 were used per rectum. The clinic was evaluated on the Disease activity index scale. The expression of MPO and TNFa, the content of neutrophils, lymphocytes, eosinophils, histiocytes, plasmocytes, fibroblasts, ulcerative defect, tissue damage index were determined in the focus of colon injury. The study was carried out on days 2, 4 and 6.With EC, DAI increases for the entire day, MPO and TNFa increase in the lesion, ulcerative defect isfixed, neutrophil-lymphocytic infiltration increases, and TDI increases. When comparing the morphometric parameters of the alteration zone in EC under the conditions of vitamin D3 use, in contrast to the use of 5-ASA, a decrease in the number of lymphocytes, an increase in fibroblasts was revealed on day 2, a decrease in the number of plasmocytes and an increase in fibroblasts on day 4, an increase in the number of histiocytes and fibroblasts on day 6. The diameter of the ulcerative defect and the TDI index have no significant differences between the compared groups. When comparing the effectiveness of vitamin D3, in contrast to the use of 5-ASA, the MPO content is higher on day 6; the TNFa content is higher on day 4.In EC, the effects of using rectal suppositories with vitamin D3 on clinical signs, the size of the ulcerative defect, the content of MPO and TNFa in the lesion are comparable to the effects of using rectal suppositories with 50 mg of 5-ASA; more pronounced with respect to the dynamics of the cellular composition of the lesion of the colon

Early vascular remodeling role in arterial hypertension pathogenesis among young patients

Aim. To investigate vascular wall stiffness in young patients, for examining early vascular remodeling role in arterial hypertension (AH) pathogenesis in young age. Material and methods. The study included 291 individuals: 169 normotensives and 122 AH patients aged 16-34 years. All participants underwent volume sphygmography (VaSera-1000, «Fukuda Denshi», Japan), blood pressure (BP) measurement in upper and lower extremity basins, elastic and muscular vessel elasticity assessment. Results. In young age, high elastic vessel stiffness was observed in 13.6% of normotensives, and in 50% of AH patients. For muscular vessels, this parameter was 11.2% and 35%, respectively. In systolo-diastolic AH, muscular vessel stiffness increased, in isolated systolic AH (ISAH) – elastic or elastic and muscular vessel stiffness is increased. About 50% of young ISAH individuals had increased BP on upper extremities only – «pseudo-hypertension». Conclusion. Early vascular remodeling plays an important role in AH pathogenesis among young people

Research of functional respiratory status in rehabilitation and prevention of the patients with industrially conditioned chronic bronchitis

Исследованы показатели функции внешнего дыхания у больных с производственно обусловленным хроническим бронхитом при проведении медицинской реабилитации с использованием магнитотерапии и рефлексотерапии. The functional respiratory status of patients with industrially conditioned chronic bronchitis was researched. The use of reflexotherapy and magnetotherapy in rehabilitations programs lead to prevention of chronic bronchitis

ИССЛЕДОВАНИЕ ФУНКЦИИ ВНЕШНЕГО ДЫХАНИЯ У БОЛЬНЫХ С ПРОИЗВОДСТВЕННО ОБУСЛОВЛЕННЫМ ХРОНИЧЕСКИМ БРОНХИТОМ ПРИ ПРОВЕДЕНИИ МЕДИЦИНСКОЙ РЕАБИЛИТАЦИИ

The functional respiratory status of patients with industrially conditioned chronic bronchitis was researched. The use of reflexotherapy and magnetotherapy in rehabilitations programs lead to prevention of chronic bronchitis.Исследованы показатели функции внешнего дыхания у больных с производственно обусловленным хроническим бронхитом при проведении медицинской реабилитации с использованием магнитотерапии и рефлексотерапии

Research of functional respiratory status in rehabilitation and prevention of the patients with industrially conditioned chronic bronchitis

Исследованы показатели функции внешнего дыхания у больных с производственно обусловленным хроническим бронхитом при проведении медицинской реабилитации с использованием магнитотерапии и рефлексотерапии. The functional respiratory status of patients with industrially conditioned chronic bronchitis was researched. The use of reflexotherapy and magnetotherapy in rehabilitations programs lead to prevention of chronic bronchitis

The new differential diagnostic test for the lichenoid drug eruption

The differential diagnosis between lichenoid drug eruption (LDE) and lichen planus (LP) is difficult due to similar clinical and histological signs, but important for treatment and prognosis. The purpose of this study was to propose the new diagnosis method for differentiate LDE from lichen planus. During 2015-2018, 20 patients with confirmed LDE, 13 patients with LP and 134 controls were examined and treated at the Lenoblcenter. All enrolled patients were underwent the injection of 0.5 mL of the 2% lidocaine solution by insulin syringe into the papule with following histological examination. The formation of a blister (bulla) at the site of injection was considered a positive test result. Among LDE 18/20 patients were found positive for developing blister (bulla), 2 results were questionable. In 12 of 13 LP patents, bulla on the site of injection was not identified, the result of 1 patient was non-specific. All control patients were negative for the proposed test. The histological sections showed that the bulla has corresponded to the separation of the epidermis from the dermis. Intracutaneous injection of 0.5 mL of lidocaine into the papule is an easy highly specific and sensitive method to differentiate LDE from LP. This article is protected by copyright. All rights reserved