4 research outputs found

    Renal morphometric evaluation by ultrasonographic techniques in normal female Saanen goats (Capra hircus)

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    A utilização de tĂ©cnicas ultrassonogrĂĄficas na ĂĄrea de Medicina VeterinĂĄria estĂĄ cada vez mais presente e a capacitação nesta ĂĄrea tornou-se indispensĂĄvel para o clĂ­nico, auxiliando-o na obtenção de informaçÔes rĂĄpidas e valiosas das afecçÔes patolĂłgicas que podem acometer os animais. O exame ultrassonogrĂĄfico renal revelou-se de grande importĂąncia neste Ăąmbito, com o objetivo de avaliar e mensurar os parĂąmetros morfomĂ©tricos renais normais de fĂȘmeas caprinas (Capra hircus). Por meio de tĂ©cnicas ultrassonogrĂĄficas procedeu-se o estudo de 30 fĂȘmeas da raça Saanen, divididas em trĂȘs grupos: fĂȘmeas com idade inferior a 6 meses (3,0±1,0 meses), de 6-18 meses (9,0±4,3 meses) e com idade superior a 18 meses (46,3±17,4 meses). Realizaram-se imagens dos rins, em secçÔes longitudinais, medidas de comprimento e largura e, em secçÔes transversais, medidas de altura (ou espessura). Com estes valores calcularam-se volumes renais, corticais e medulares, alĂ©m da relação cortico-medular. Com relação ao comprimento renal os grupos com idade inferior a 6 meses, de 6-18 meses e com idade superior a 18 meses obtiveram mĂ©dia e desvio padrĂŁo de 4,20±0,36cm, 5,56±0,40cm e 6,77±0,64cm, respectivamente. Tratando-se do volume renal, estes grupos apresentaram mĂ©dia e desvio padrĂŁo de 17,02±3,99cmÂł, 19,99±5,86cmÂł; e, 41,23±13,05cmÂł. Comparou-se a equivalĂȘncia mĂ©trica das mĂ©dias entre os dois rins de forma que os parĂąmetros volumĂ©tricos e lineares renais com diferença entre si sĂŁo comprimento renal, volume renal e volume cortical para o grupo de fĂȘmeas com idade de 6-18 meses, e comprimento renal e comprimento medular para o grupo com idade superior a 18 meses. Entre diferentes grupos observou-se que somente o comprimento medular esquerdo apresentou mĂ©dia equivalente em todos os grupos, ou seja, entre o grupo com idade inferior a 6 meses e o grupo com idade de 6-18 meses e, entre este Ășltimo e o grupo com idade superior a 18 meses. Os resultados mostraram correlaçÔes diretas e positivas entre peso corporal e idade com os parĂąmetros lineares e volumĂ©tricos, a relação cortico-medular esquerda foi a Ășnica que apresentou correlação significativa com o peso (r= -0,365; P = 0,047). Para aqueles parĂąmetros que apresentaram correlação significativa foi realizada anĂĄlise de regressĂŁo, obtendo-se a linha de melhor ajuste das variĂĄveis

    Agenesis of the seventh cervical vertebra with spinal cord compression in a goat

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    A 4-year-old male goat was presented to the Hospital of Bovines and Small Ruminants, University of SĂŁo Paulo - Brazil, showing fasciculation in all limbs, ataxia progressing to paralysis and opisthotonos. After determination of the vital parameters and the specific evaluation of the nervous system, sensitivity in the region corresponding to the sixth cervical vertebrae (C6) and first thoracic vertebrae (T1) was observed on palpation. Further investigation using X-ray, myelography, and ultrasound revealed the decrease of the intervertebral space between C6 and T1, the presence of spondylosis and the absence of the seventh cervical vertebra (C7), which contained only the vertebral arch and local spinous process and the compression of the spinal cord. Goat congenital malformations are underdiagnosed, therefore, requires further discussion, and studies regarding the genetic variations

    Evaluation of a quality improvement intervention to reduce anastomotic leak following right colectomy (EAGLE): pragmatic, batched stepped-wedge, cluster-randomized trial in 64 countries

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    Background Anastomotic leak affects 8 per cent of patients after right colectomy with a 10-fold increased risk of postoperative death. The EAGLE study aimed to develop and test whether an international, standardized quality improvement intervention could reduce anastomotic leaks. Methods The internationally intended protocol, iteratively co-developed by a multistage Delphi process, comprised an online educational module introducing risk stratification, an intraoperative checklist, and harmonized surgical techniques. Clusters (hospital teams) were randomized to one of three arms with varied sequences of intervention/data collection by a derived stepped-wedge batch design (at least 18 hospital teams per batch). Patients were blinded to the study allocation. Low- and middle-income country enrolment was encouraged. The primary outcome (assessed by intention to treat) was anastomotic leak rate, and subgroup analyses by module completion (at least 80 per cent of surgeons, high engagement; less than 50 per cent, low engagement) were preplanned. Results A total 355 hospital teams registered, with 332 from 64 countries (39.2 per cent low and middle income) included in the final analysis. The online modules were completed by half of the surgeons (2143 of 4411). The primary analysis included 3039 of the 3268 patients recruited (206 patients had no anastomosis and 23 were lost to follow-up), with anastomotic leaks arising before and after the intervention in 10.1 and 9.6 per cent respectively (adjusted OR 0.87, 95 per cent c.i. 0.59 to 1.30; P = 0.498). The proportion of surgeons completing the educational modules was an influence: the leak rate decreased from 12.2 per cent (61 of 500) before intervention to 5.1 per cent (24 of 473) after intervention in high-engagement centres (adjusted OR 0.36, 0.20 to 0.64; P < 0.001), but this was not observed in low-engagement hospitals (8.3 per cent (59 of 714) and 13.8 per cent (61 of 443) respectively; adjusted OR 2.09, 1.31 to 3.31). Conclusion Completion of globally available digital training by engaged teams can alter anastomotic leak rates. Registration number: NCT04270721 (http://www.clinicaltrials.gov)
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