874 research outputs found
Osaka’s Thirteen Buddhas: The Proliferation of Modern Japanese Pilgrimage Routes Extended Abstract
Osaka’s Thirteen Buddha Pilgrimage is a route through the greater Osaka area to Buddhist temples. Thirteen Buddha pilgrimage routes have experienced growth in participation over the past few years. This new popularity has increased the number of thirteen Buddha pilgrimages routes. This proliferation in routes are a phenomenon, which deserves attention because pilgrimage participation is often used not only as an illustration of a specific religious practice but also a significant variable in the continuing discourse about Japan’s secularization (Reader 2012). This study investigates more specifically Osaka’s thirteen Buddha pilgrimage sites and how each has become a location for multiple pilgrimage routes of various types as well as single-site pilgrimage miniaturizations. This proliferation of pilgrimage routes illustrates the complicated modern landscape of Japanese pilgrimage where interest in pilgrimage may be out paced by keen competition among increasing pilgrimage route possibilities
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Terasaki spiral ramps and intracellular diffusion
The sheet-like endoplasmic reticulum (ER) of eukaryotic cells has been found to be riddled with spiral dislocations, known as 'Terasaki ramps', in the vicinity of which the doubled bilayer membranes which make up ER sheets can be approximately modeled by helicoids. Here we analyze diffusion on a surface with locally helicoidal topological dislocations, and use the results to argue that the Terasaki ramps facilitate a highly efficient transport of water-soluble molecules within the lumen of the endoplasmic reticulum
The Proliferation, Commercialization, and Secularization of the Seven Gods of Good Fortune Pilgrimages in Modern Japan
Osaka’s Thirteen Buddha Pilgrimage is a route through the greater Osaka area to Buddhist temples. Thirteen Buddha pilgrimage routes have experienced growth in participation over the past few years. This new popularity has increased the number of thirteen Buddha pilgrimages routes. This proliferation in routes are a phenomenon, which deserves attention because pilgrimage participation is often used not only as an illustration of a specific religious practice but also a significant variable in the continuing discourse about Japan’s secularization (Reader 2012). This study investigates more specifically Osaka’s thirteen Buddha pilgrimage sites and how each has become a location for multiple pilgrimage routes of various types as well as single-site pilgrimage miniaturizations. This proliferation of pilgrimage routes illustrates the complicated modern landscape of Japanese pilgrimage where interest in pilgrimage may be out paced by keen competition among increasing pilgrimage route possibilities
Aggregation-fragmentation-diffusion model for trail dynamics
We investigate statistical properties of trails formed by a random process incorporating aggregation, fragmentation, and diffusion. In this stochastic process, which takes place in one spatial dimension, two neighboring trails may combine to form a larger one, and also one trail may split into two. In addition, trails move diffusively. The model is defined by two parameters which quantify the fragmentation rate and the fragment size. In the long-time limit, the system reaches a steady state, and our focus is the limiting distribution of trail weights. We find that the density of trail weight has power-law tail P(w)~w-γ for small weight w. We obtain the exponent γ analytically and find that it varies continuously with the two model parameters. The exponent γ can be positive or negative, so that in one range of parameters small-weight trails are abundant and in the complementary range they are rare
Achieving Canada-United States Economic Competitiveness through Regulatory Convergence - A Common Cause Agency
Persistent stability of a chaotic system
We report that trajectories of a one-dimensional model for inertial particles in a random velocity field can remain stable for a surprisingly long time, despite the fact that the system is chaotic. We provide a detailed quantitative description of this effect by developing the large-deviation theory for fluctuations of the finite-time Lyapunov exponent of this system. Specifically, the determination of the entropy function for the distribution reduces to the analysis of a Schrödinger equation, which is tackled by semi-classical methods. The system has generic instability properties, and we consider the broader implications of our observation of long-term stability in chaotic systems
Achieving Canada-United States Economic Competitiveness through Regulatory Convergence - A Common Cause Agency
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Persistent features of intermittent transcription
Single-cell RNA sequencing is a powerful tool for exploring gene expression heterogeneity, but the results may be obscured by technical noise inherent in the experimental procedure. Here we introduce a novel parametrisation of sc-RNA data, giving estimates of the probability of activation of a gene and its peak transcription rate, which are agnostic about the mechanism underlying the fluctuations in the counts. Applying this approach to single cell mRNA counts across different tissues of adult mice, we find that peak transcription levels are approximately constant across different tissue types, in contrast to the gene expression probabilities which are, for many genes, markedly different. Many genes are only observed in a small fraction of cells. An investigation of correlation between genes activities shows that this is primarily due to temporal intermittency of transcription, rather than some genes being expressed in specialised cell types. Both the probability of activation and the peak transcription rate have a very wide ranges of values, with a probability density function well approximated by a power law. Taken together, our results indicate that the peak rate of transcription is a persistent property of a gene, and that differences in gene expression are modulated by temporal intermittency of the transcription
Polysomally protected viruses
It is conceivable that an RNA virus could use a polysome, that is, a string of ribosomes covering the RNA strand, to protect the genetic material from degradation inside a host cell. This paper discusses how such a virus might operate, and how its presence might be detected by ribosome profiling. There are two possible forms for such a polysomally protected virus, depending upon whether just the forward strand or both the forward and complementary strands can be encased by ribosomes (these will be termed type 1 and type 2, respectively). It is argued that in the type 2 case the viral RNA would evolve an ambigrammatic property, whereby the viral genes are free of stop codons in a reverse reading frame (with forward and reverse codons aligned). Recent observations of ribosome profiles of ambigrammatic narnavirus sequences are consistent with our predictions for the type 2 case
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