1,122 research outputs found
Condition-specific outcome measures for low back pain: Part I: Validation
A literature review of the nine most widely used, condition-specific, self-administered assessment questionnaires for low back pain has been undertaken. General and historic aspects, reliability, responsiveness and minimum clinically important difference, external validity, floor and ceiling effects and available languages were analysed for the nine most-used outcome tools. When considering which condition-specific measure to employ, the present overview on assessment tools should provide the necessary information to define the technical aspects of the nine questionnaires. These criteria, however, are only part of the consideration. In part II the construction of these scales in relationship to the measurement domains will be evaluate
Condition-specific outcome measures for low back pain: Part II: Scale construction
A literature review of the most widely used, condition-specific, self-administered assessment questionnaires for low back pain has been undertaken. In part I, technical issues such as validity, reliability, availability and comparability were analyzed for the nine most widely used outcome tools. This second part focuses on the content and wording of questions and answers in each of the nine questionnaires, and an analysis of the different score results is performed. The issue of score bias is discussed and suggestions are given in order to increase the construct validity in the practical use of the individual questionnaire
Postnatal corticosteroid usage in United Kingdom and Ireland neonatal units:Postnatal corticosteroid usage
Corticosteroids in infant chronic lung disease
Chronic lung disease (CLD), defined as chronic oxygen dependency at 36 weeks postmenstrual age, is increasing and associated with chronic respiratory morbidity and high health care utilisation at follow up. Many strategies, tested in randomised trials, have failed to reduce CLD. In contrast, corticosteroids if given systemically within the first two weeks after birth reduce CLD and may also favourably influence survival. Unfortunately, systemically administered corticosteroids have many acute side-effects and adversely affect long term neurodevelopmental outcome. If given by inhalation, corticosteroids have fewer adverse effects, but are less efficacious. Further research is required to accurately identify infants at highest risk of developing CLD, the corticosteroid dosage associated with a positive risk: benefit ratio and preferably a safer and more effective alternative therapy
Dehiscence of detached internal limiting membrane in eyes with myopic traction maculopathy with spontaneous resolution
Background: Idjwi, an island of approximately 220,000 people, is located in eastern DRC and functions semi-autonomously under the governance of two kings (mwamis). At more than 8 live births per woman, Idjwi has one of the highest total fertility rates (TFRs) in the world. Rapid population growth has led to widespread environmental degradation and food insecurity. Meanwhile family planning services are largely unavailable.Methods: At the invitation of local leaders, we conducted a representative survey of 2,078 households in accordance with MEASURE DHS protocols, and performed ethnographic interviews and focus groups with key informants and vulnerable subpopulations. Modelling proximate determinates of fertility, we evaluated how the introduction of contraceptives and/or extended periods of breastfeeding could reduce the TFR.Results: Over half of all women reported an unmet need for spacing or limiting births, and nearly 70% named a specific modern method of contraception they would prefer to use; pills (25.4%) and injectables (26.5%) were most desired. We predicted that an increased length of breastfeeding (from 10 to 21 months) or an increase in contraceptive prevalence (from 1% to 30%), or a combination of both could reduce TFR on Idjwi to 6, the average desired number of children. Increasing contraceptive prevalence to 15% could reduce unmet need for contraception by 8%.Conclusions: To meet women’s need and desire for fertility control, we recommend adding family planning services at health centers with NGO support, pursuing a community health worker program, promoting extended breastfeeding, and implementing programs to end sexual- and gender-based violence toward women
A comparison of analytical and numerical model predictions of shallow soil temperature variation with experimental measurements
The file attached to this record is the author's final peer reviewed version. The Publisher's final version can be found by following the DOI link.In several fields of enquiry such as geothermal energy, geology and agriculture, it is of interest to study the thermal behaviour of shallow soils. For this, several analytical and numerical methodologies have been proposed to analyse the temperature variation of the soil in the short and long term. In this paper, a comparative study of different models (sinusoidal, semi-infinite and finite difference method) is conducted to estimate the shallow soil temperature variation in the short and long term. The models were compared with hourly experimental measured data of soil temperature in Leicester, UK, at depths between 0.75 and 2.75 m. The results show that the sinusoidal model is not appropriate to evaluate the short-term temperature variations, such as hourly or daily fluctuations. Likewise, this model is highly affected by the undisturbed ground temperature and can lead to very high errors. Regarding the semi-infinite model, it is accurate enough to predict the short-term temperature variation. However, it is useless to predict the long-term variation at depths greater than 1 m. The finite difference method (FDM) considering the air temperature as a boundary condition for the soil surface is the most accurate approach for estimating both short and long-term temperature variations while the FDM with heat flux as boundary condition is the least accurate approach due to the uncertainty of the assumed parameters. The ranges of errors for the sinusoidal, semi-infinite and FDM are found to be from 76.09 to 142.13%, 12.11 to 104.88% and 1.82 to 28.14% respectively
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