Human acclimation and acclimatization to heat A compendium of research

Annotated bibliography on human acclimation and acclimatization to hea

Adaptation to prolonged bedrest in man: A compendium of research

A compilation of major studies that describe the clinical observations and elucidate the physiological mechanisms of the adaptive process of man undergoing prolonged bed rest is presented. Additional studies are included that provide background information in the form of reviews or summaries of the process. Wherever possible a detailed annotation is provided under the subheadings: (1) purpose, (2) procedure and methods, (3) results, and (4) conclusions. Additional references are provided in a selected bibliography

Effects of dehydration on performance in man: Annotated bibliography

A compilation of studies on the effect of dehydration on human performance and related physiological mechanisms. The annotations are listed in alphabetical order by first author and cover material through June 1973

Thermistor holder for skin-temperature measurements

Sensing head of thermistor probe is supported in center area of plastic ring which has tabs so that it can be anchored in place by rubber bands or adhesive tapes. Device attaches probes to human subjects practically, reliably, and without affecting characteristics of skin segment being measured

Sweat collection capsule

A sweat collection capsule permitting quantitative collection of sweat is described. The device consists of a frame held immobile on the skin, a closure secured to the frame and absorbent material located next to the skin in a cavity formed by the frame and the closure. The absorbent material may be removed from the device by removing the closure from the frame while the frame is held immobile on the skin

The physiology and biochemistry of total body immobilization in animals: A compendium of research

Major studies that describe the physiological and biochemical mechanisms which operate during total body restraint (confinement in cages for example) are presented. The metabolism and behavior of various animals used in medical research (dogs, monkeys, rats, fowl) was investigated and wherever possible a detailed annotation for each study is provided under the subheadings: (a) purposes, (b) procedures and methods, (c) results, and (d) conclusions. Selected references are also included

New system for bathing bedridden patients

Multihead shower facility can be used with minimal patient handling. Waterproof curtain allows patient to bathe with his head out of shower. He can move completely inside shower to wash his face and hair. Main advantage of shower system is time saved in giving bath

High-resolution mapping of cancer cell networks using co-functional interactions.

Powerful new technologies for perturbing genetic elements have recently expanded the study of genetic interactions in model systems ranging from yeast to human cell lines. However, technical artifacts can confound signal across genetic screens and limit the immense potential of parallel screening approaches. To address this problem, we devised a novel PCA-based method for correcting genome-wide screening data, bolstering the sensitivity and specificity of detection for genetic interactions. Applying this strategy to a set of 436 whole genome CRISPR screens, we report more than 1.5 million pairs of correlated "co-functional" genes that provide finer-scale information about cell compartments, biological pathways, and protein complexes than traditional gene sets. Lastly, we employed a gene community detection approach to implicate core genes for cancer growth and compress signal from functionally related genes in the same community into a single score. This work establishes new algorithms for probing cancer cell networks and motivates the acquisition of further CRISPR screen data across diverse genotypes and cell types to further resolve complex cellular processes

Physiologic responses to water immersion in man: A compendium of research

A total of 221 reports published through December 1973 in the area of physiologic responses to water immersion in man were summarized. The author's abstract or summary was used whenever possible. Otherwise, a detailed annotation was provided under the subheadings: (1) purpose, (2) procedures and methods, (3) results, and (4) conclusions. The annotations are in alphabetical order by first author; author and subject indexes are included. Additional references are provided in the selected bibliography