Review of acute rheumatic fever and rheumatic heart disease among Indigenous Australians

This review is intended to provide an authoritative, up-to-date account of acute rheumatic fever and rheumatic heart disease among Indigenous people.PrefaceThis review of acute rheumatic fever and rheumatic heart disease among Indigenous Australians has been prepared by the Australian Indigenous HealthInfoNet as a part of our contributions to ‘closing the gap’ in health between Indigenous people and other Australians by making relevant, high quality knowledge and information easily accessible to policy makers, health service providers, program managers, clinicians, researchers and the general community. The review is an example of the HealthInfoNet’s translational research, defined as ‘comprehensive applied research that strives to translate the available knowledge and render it operational’.The main purpose of the review, which follows the model of narrative reviews/syntheses, is to provide an authoritative, up-to-date review of acute rheumatic fever and rheumatic heart disease among Indigenous people that: (1) is a valuable overview for people working in the area; and (2) assists in the development/refinement of policies, strategies and programs.Research for the review involved the collection, collation, and analysis of a wide range of relevant information, including both published and unpublished material. Sources include the full range of relevant literature, including journal articles and other relevant publications, the vast majority of which are accessible via the HealthInfoNet’s Australian Indigenous HealthBibliography. This bibliography, with more than more 20,000 entries, captures all relevant journal articles, books, book chapters and reports (including the ‘grey’ literature).As well as the relevant journal literature, the HealthInfoNet’s reviews draw on important government reports, particularly those produced by the Australian Bureau of Statistics (ABS), the Australian Institute of Health and Welfare (AIHW) and the Steering Committee for the Review of Government Service Provision (SCRGSP), and reports in the Aboriginal and Torres Strait Islander health performance framework series. These reports, prepared by the Australian Health Ministers’ Advisory Council (AHMAC) in 2006, 2008, 2011 and 2012, are accompanied by substantial detailed analyses, which are accessible on the AIHW website. The HealthInfoNet’s reviews also draw on information from the main administrative data collections (such as the birth and death registration systems and the hospital inpatient collections) and national surveys. Information from these sources has been published mainly in government reports, particularly those produced by the ABS and the AIHW.After providing the context of acute rheumatic fever and rheumatic heart disease, the body of the review outlines the extent of acute rheumatic fever and rheumatic heart disease among Indigenous people, provides an overview of the various contributing factors, considers prevention and management, summarises a number of relevant policies and strategies, and provides some brief concluding comments. Rather than commence with an executive summary, the review is preceded by a section devoted to ‘Key facts’, which presents the summarised information in a more concise form. &nbsp

Plain language review of physical activity among Indigenous Australians

This review provides information on physical activity among Aboriginal and Torres Strait Islander people. It is a valuable overview for people working in the area and aims to assists in the development/refinement of policies, strategies and programs. This review of physical activity among Aboriginal and Torres Strait Islander Australians has been prepared by the Australian Indigenous HealthInfoNet as a part of our contributions to \u27closing the gap\u27 in health between Aboriginal and Torres Strait Islander people and other Australians by making relevant, high quality knowledge and information easily accessible to policy makers, health service providers, program managers, clinicians, researchers and the general community. This Plain language review of physical activity among Aboriginal and Torres Strait Islander Australians is based on the Review of physical activity among Indigenous Australians (2013) by Caitlin Gray, Rona Macniven and Neil Thomson

Plain language review of cardiovascular health among Indigenous Australians

This document summarises, in plain language, information about the cardiovascular health status of Aboriginal and Torres Strait Islander peoples. It provides information about : the various cardiovascular diseases and their risk factors the extent of cardiovascular disease (CVD) among Aboriginal and Torres Strait Islander people, including prevalence, hospitalisation and death rates types and levels of care for Aboriginal and Torres Strait Islander CVD patients strategies and programs that aim to improve the cardiovascular health status of Aboriginal and Torres Strait Islander people. The publication is a plain language summary of the Review of cardiovascular health among Indigenous Australians (2013) by Caitlin Gray, Alex Brown and Neil Thomson

Review of physical activity among Indigenous people

Physical activity is important for all Australians, particularly in the prevention, management and treatment of chronic conditions, and for social and emotional wellbeing. Chronic health conditions, including cardiovascular conditions, endocrine conditions (such as diabetes), and certain cancers, account for 70% of the observed difference in the burden of disease between the Indigenous and non-Indigenous populations. Modifiable risk factors, particularly behavioural determinants such as physical activity, can help to reduce the extent and impact of these conditions, and assist in the prevention, management and treatment of disease. The levels and impacts of physical inactivity are greater for Indigenous people than they are for other Australians. Physical inactivity has been cited as the second leading cause of disease burden in Australia, and the third leading cause of disease burden for Indigenous people

Industry‐Dominated Science Advisory Boards Are Perceived To Be Legitimate…But Only When They Recommend More Stringent Risk Management Policies

In 2017, the US Environmental Protection Agency (EPA) was criticized for two controversial directives that restricted the eligibility of academic scientists to serve on the agency’s key science advisory boards (SABs). The EPA portrayed these directives as necessary to ensure the integrity of the SAB. Critics portrayed them as a tactic by the agency to advance a more industry‐friendly deregulatory agenda. With this backdrop, this research examined board composition and its effect on the perceived legitimacy of risk management recommendations by the SAB. In an experiment, we presented participants with hypothetical EPA SABs composed of different proportions of academic and industry scientists. We then asked participants to rate their satisfaction with, and the legitimacy of, these boards in light of their decisions in scenarios based on actual EPA SAB deliberations. Participants perceived higher levels of satisfaction and legitimacy when SABs made more stringent risk management recommendations. While SABs dominated by industry scientists were perceived to be more strongly motivated to protect business interests, we found no effect of board composition on perceptions of satisfaction and legitimacy. These results are consistent with prior research on decision quality that suggests people use normative outcomes as a heuristic for assessing the quality of deliberations. Moreover, these results suggest that members of the public are supportive of federal SABs regardless of their composition, but only if they take actions that are consistent with normative expectations.Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/163630/2/risa13540.pdfhttp://deepblue.lib.umich.edu/bitstream/2027.42/163630/1/risa13540_am.pd

Toll-like receptor gene variants and bacterial vaginosis among HIV-1 infected and uninfected African women.

Bacterial vaginosis (BV) is a common vaginal syndrome associated with altered microflora that increases the risk of preterm delivery and acquisition of sexually transmitted diseases. The cause of BV is unknown although toll-like receptors (TLRs), that are central to innate immune responses, may be important. We evaluated associations between TLR SNPs and BV among HIV-1 infected and uninfected African women. Logistic regression was used to assess associations between SNPs (N=99) in TLRs 2-4, 7-9 and BV (as classified by Nugent's criteria). Among HIV-1 uninfected women, TLR7 rs5743737 and TLR7 rs1634323 were associated with a decreased risk of BV, whereas TLR7 rs179012 was associated with an increased risk. TLR2 SNP rs3804099 was associated with a decreased risk of BV among HIV-1 infected women. Our findings indicate that there may be differences in TLR association with BV among HIV-1 infected and HIV-1 uninfected women

Potential changes in the distribution of Carnegiea gigantea under future scenarios

Over the last decades several studies have identified that the directional changes in climate induced by anthropogenic emissions of greenhouse gases are affecting the ecology of desert ecosystems. In the Southwest United States, the impacts of climate change to plant abundance and distribution have already been reported, including in the Sonoran Desert ecosystem, home of the iconic Saguaro (Carnegiea gigantea). Hence, there is an urgent need to assess the potential impacts of climate change on the saguaro. The goals of this study are to provide a map of actual habitat suitability (1), describe the relationships between abiotic predictors and the saguaro distribution at regional extents (2), and describe the potential effect of climate change on the spatial distribution of the saguaro (3). Species Distribution Modeling (SDM) was used to investigate the relationships between abiotic variables and the Saguaro distribution. SDMs were calibrated using presence records, 2,000 randomly-generated pseudo absences, and ten abiotic variables. Of these, annual precipitation and max temperature of the warmest month was found to have the greatest relative influence on saguaro distribution. SDMs indicated that 6.9% and 8.1% of the current suitable habitat is predicted to be lost by 2050 and 2070, respectively. Therefore, predicted changes in climate may result in a substantial contraction of the suitable habitat for saguaro over the next century. By identifying the drivers of saguaro distribution and assessing potential changes in habitat suitability due to climate change, this study will help practitioners to design more comprehensive strategies to conserve the saguaro in the face of climate change