9,202 research outputs found
LaRC design analysis report for National Transonic Facility for 304 stainless steel tunnel shell. Volume 4S: Thermal analysis
For abstract, see N76-33552
LaRC design analysis report for National Transonic Facility for 304 stainless steel tunnel shell. Volume 7S: Special studies
For abstract, see N76-33552
LaRC design analysis report for national transonic facility for 9% nickel tunnel shell. Volume 7: Special studies
For abstract, see N76-33543
LaRC design analysis report for National Transonic Facility for 9% nickel tunnel shell. Volume 3: Finite element analysis of plenum region including side access reinforcement, side access door and angle of attack penetration
For abstract, see N76-33543
LaRC design analysis report for National Transonic Facility for 304 stainless steel tunnel shell. Volume 2S: Finite element analysis of corners no. 3 and no. 4
For abstract, see N76-33552
Design considerations for attaining 250-knot test velocities at the aircraft landing dynamics facility
Preliminary design studies are presented which consider the important parameters in providing 250 knot test velocities at the Aircraft Landing Dynamics Facility. Four major components of this facility are: the hydraulic jet catapult, the test carriage structure, the reaction turning bucket, and the wheels. Using the hydraulic-jet catapult characteristics, a target design point was selected and a carriage structure was sized to meet the required strength requirements. The preliminary design results indicate that to attain 250 knot test velocities for a given hydraulic jet catapult system, a carriage mass of 25,424 kg (56,000 lbm.) cannot be exceeded
Scientific questions for the exploration of the terrestrial planets and Jupiter - Advanced planetary missions technology program Progress report
Scientific questions and experimental design for planetary exploration of Jupiter, Mars, Mercury, and Venu
Triadin Knockout Syndrome Is Absent in a Multi-Center Molecular Autopsy Cohort of Sudden Infant Death Syndrome and Sudden Unexplained Death in the Young and Is Extremely Rare in the General Population
Background:
Triadin knockout syndrome (TKOS) is a potentially lethal arrhythmia disorder caused by recessively inherited null variants in TRDN-encoded cardiac triadin. Despite its malignant phenotype, the prevalence of TKOS in sudden infant death syndrome and sudden unexplained death in the young is unknown.
Methods:
Exome sequencing was performed on 599 sudden infant death syndrome and 258 sudden unexplained death in the young cases. Allele frequencies of all TRDN null variants identified in the cardiac-specific isoform of TRDN in the Genome Aggregation Database were used to determine the estimated prevalence and ethnic distribution of TKOS.
Results:
No triadin null individuals were identified in 599 sudden infant death syndrome and 258 sudden unexplained death in the young exomes. Using the Genome Aggregation Database, we estimate the overall prevalence of TKOS to be ≈1:22.7 million individuals. However, TKOS prevalence is 5.5-fold higher in those of African descent (≈1:4.1 million).
Conclusions:
TKOS is an exceedingly rare clinical entity that does not contribute meaningfully to either sudden infant death syndrome or sudden unexplained death in the young. However, despite its rarity and absence in large sudden death cohorts, TKOS remains a malignant and potentially lethal disorder which requires further research to better care for these patients
LaRC design analysis report for national transonic facility for 9% nickel tunnel shell. Volume 6: Fatigue analysis
For abstract, see N76-33543
LaRC design analysis report for National Transonic Facility for 304 stainless steel tunnel shell. Volume 5S: Finite element and numerical integration analyses of the bulkhead region
For abstract, see N76-33552
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