Dielectric properties of Mars' surface: Proposed measurement on a Mars lander

Recent studies of missions to Mars (MESUR by NASA and Marsnet by ESA) have suggested the development of semihard landers. One type was to be extremely basic, consisting mainly of a meteorological package, but with the possibility of other small, low-mass, low-power instruments. In particular, this type of lander was also considered for the exploration of the polar regions. Two methods to investigate the surface material at the landing site are discussed. Both measure the dielectric constant epsilon of the ground material. This information can then be used to elucidate the surface composition and structure. The determination of the permittivity would be of high scientific value, especially in the case of a landing on the polar ice

The flight of the bumblebee: vacuum solutions of a gravity model with vector-induced spontaneous Lorentz symmetry breaking

We study the vacuum solutions of a gravity model where Lorentz symmetry is spontaneously broken once a vector field acquires a vacuum expectation value. Results are presented for the purely radial Lorentz symmetry breaking (LSB), radial/temporal LSB and axial/temporal LSB. The purely radial LSB result corresponds to new black hole solutions. When possible, Parametrized Post-Newtonian (PPN) parameters are computed and observational boundaries used to constrain the Lorentz symmetry breaking scale.Comment: 12 pages, 2 figure

Solar wind control of auroral substorm onset locations observed with the IMAGE-FUV imagers

peer reviewedThe FUV imagers on board the IMAGE satellite provide multispectral snapshots of the polar region every 2 min. The combination of the Wide-Angle Imaging Camera (WIC) with SI12 (Doppler shifted Lyman-alpha) and SI13 (135.6 nm) spectral imagers is used to discriminate between the electron and the proton aurora. We describe a statistical study of the location of 78 substorms observed close to the 2000-2001 winter solstice. The latitudinal distribution of the onsets observed with WIC is asymmetric with a median at 65.6° MLAT and a full width at half maximum (FWHM) of 3.5°. Their local time distribution is concentrated between 2000 and 0200 MLT with a median at 23.4 +/- 0.3 hours MLT and a FWHM of 1.8 hours. No statistically significant difference is found in the spatial distribution of the proton and electron onsets. All onsets take place within a region of preexisting proton precipitation, indicating that substorm initiation occurs in regions of stretched but dipole-like field lines that cross the equatorial plane close to the Earth. Latitudes of substorm onsets are located at a variable distance from the poleward FUV auroral boundary but remain at a nearly constant distance from the equatorward limit of both proton and electron auroral ovals. The magnetic latitudes of the onsets are correlated with some of the solar wind plasma properties measured by the ACE satellite prior to the substorm breakup. In particular, a clear anticorrelation is found between the onset MLAT and the 1-hour averaged solar wind dynamic pressure. A decrease of the onset latitude is also observed for larger B intensity values. No dependence of the onset MLT on the solar wind speed is observed, in contrast to the relationship expected from the thermal catastrophe model for substorm initiation. Our results are in agreement with models locating the initial instability in the near magnetosphere such as the near-Earth current disruption models

Kaluza-Klein towers for real vector fields in flat space

We consider a free real vector field propagating in a five dimensional flat space with its fifth dimension compactified either on a strip or on a circle and perform a Kalaza Klein reduction which breaks SO(4,1) invariance while reserving SO(3,1) invariance. Taking into account the Lorenz gauge condition, we obtain from the most general hermiticity conditions for the relevant operators all the allowed boundary conditions which have to be imposed on the fields in the extra-dimension. The physical Kaluza-Klein mass towers, which result in a four-dimensional brane, are determined in the different distinct allowed cases. They depend on the bulk mass, on the parameters of the boundary conditions and on the extra parameter present in the Lagrangian. In general, they involve vector states together with accompanying scalar states.Comment: 28 pages, 4 independent table

Gravitating dyons and the Lue-Weinberg bifurcation

Gravitating t'Hooft-Polyakov magnetic monopoles can be constructed when coupling the Georgi-Glashow model to gravitation. For a given value of the Higgs boson mass, these gravitating solitons exist up to a critical value of the ratio of the vector meson mass to the Planck mass. The critical solution is characterized by a degenerate horizon of the metric. As pointed out recently by Lue and Weinberg, two types of critical solutions can occur, depending on the value of the Higgs boson mass. Here we investigate this transition for dyons and show that the Lue and Weinberg phenomenon is favorized by the presence of the electric-charge degree of freedom.Comment: RevTeX, 6 pages, 8 figure

Zika virus in Gabon (Central Africa) - 2007 : a new threat from Aedes albopictus ?

Background Chikungunya and dengue viruses emerged in Gabon in 2007, with large outbreaks primarily affecting the capital Libreville and several northern towns. Both viruses subsequently spread to the south-east of the country, with new outbreaks occurring in 2010. The mosquito species Aedes albopictus, that was known as a secondary vector for both viruses, recently invaded the country and was the primary vector involved in the Gabonese outbreaks. We conducted a retrospective study of human sera and mosquitoes collected in Gabon from 2007 to 2010, in order to identify other circulating arboviruses. Methodology/Principal Findings Sample collections, including 4312 sera from patients presenting with painful febrile disease, and 4665 mosquitoes belonging to 9 species, split into 247 pools (including 137 pools of Aedes albopictus), were screened with molecular biology methods. Five human sera and two Aedes albopictus pools, all sampled in an urban setting during the 2007 outbreak, were positive for the flavivirus Zika (ZIKV). The ratio of Aedes albopictus pools positive for ZIKV was similar to that positive for dengue virus during the concomitant dengue outbreak suggesting similar mosquito infection rates and, presumably, underlying a human ZIKV outbreak. ZIKV sequences from the envelope and NS3 genes were amplified from a human serum sample. Phylogenetic analysis placed the Gabonese ZIKV at a basal position in the African lineage, pointing to ancestral genetic diversification and spread. Conclusions/Significance We provide the first direct evidence of human ZIKV infections in Gabon, and its first occurrence in the Asian tiger mosquito, Aedes albopictus. These data reveal an unusual natural life cycle for this virus, occurring in an urban environment, and potentially representing a new emerging threat due to this novel association with a highly invasive vector whose geographic range is still expanding across the globe. Author Summary Not previously considered an important human arboviral pathogen, the epidemic capacity of Zika virus (ZIKV, a dengue-related flavivirus) was revealed by the Micronesia outbreak in 2007, which affected about 5000 persons. Widely distributed throughout tropical areas of Asia and Africa, ZIKV is transmitted by a broad range of mosquito species, most of which are sylvatic or rural, Aedes aegypti, an anthropophilic and urban species, being considered the main ZIKV epidemic vector. In a context of emerging arbovirus infections (chikungunya (CHIKV) and dengue (DENV)) in Gabon since 2007, we conducted a retrospective study to detect other, related viruses. In samples collected during the concurrent CHIKV/DENV outbreaks that occurred in the capital city in 2007, we detected ZIKV in both humans and mosquitoes, and notably the Asian mosquito Aedes albopictus that recently invaded the country and was the main vector responsible for these outbreaks. We found that the Gabonese ZIKV strain belonged to the African lineage, and phylogenetic analysis suggested ancestral diversification and spread rather than recent introduction. These findings, showing for the first time epidemic ZIKV activity in an urban environment in Central Africa and the presence of ZIKV in the invasive mosquito Aedes albopictus, raise the possibility of a new emerging threat to human health

Energy-flux relationship in the FUV Jovian aurora deduced from HST-STIS spectral observations

[1] Far ultraviolet spectral observations of the Jovian aurora have been made since 1997 with the Space Telescope Imaging Spectrograph (STIS) on board the Hubble Space Telescope at low spectral resolution. The combination of the spectral resolution with the intensity variation along the STIS slit provides information on the latitudinal variation of the precipitating auroral electron energy flux and the mean electron energy, from which the electron current density at the top of the atmosphere can also be deduced. It is found that the mean electron energies associated with the main oval lie in the range 30 - 200 keV and show a tendency to increase with the precipitating energy flux. The current densities lie in the range similar to 0.04 - 0.4 muA m(-2), consistent with previous estimates, and are also positively correlated with the energy flux. The observed relationship between the auroral time-integrated energy fluxes and the electron energies in the main oval is compatible with that expected from Knight's theory of field-aligned currents. The best agreement between the observed data and the Knight curves is obtained for an electron temperature of T-e = 2.5 keV and a source density N = 0.003 cm(-3), that is within the range of values observed in the equatorial plane during the Voyager flybys. No systematic dependence of the electron energy with magnetic local time is found, but the morning sector around 0800 MLT shows greater variability than other regions of the oval. Analysis of time-tagged data shows that the main oval energy flux usually varies steadily over the several minute intervals of observation and that the mean electron energy usually undergoes correlated variations such that the current density remains relatively constant. It is shown that these overall properties are also consistent with Knight's theory of auroral electron acceleration associated with field-aligned current flow, from which it is inferred that the temporal variations observed are often due to slow changes in the magnetospheric "source'' electron parameters in the presence of near-steady magnetosphere-ionosphere coupling currents. By contrast, time-integrated emissions in the polar region are found to be associated with similar mean electron energies to the main oval but with typically smaller energy fluxes and current densities. Pressure balance arguments are advanced, which indicate that the brighter of these emissions must be associated with an auroral acceleration mechanism perhaps similar to that operative in the main oval, while it remains possible that the weaker emissions could result from precipitation from a quasi-isotropic hot magnetospheric electron source

The association between hospital variation in curative treatment for esophagogastric cancer and health-related quality of life and survival

Background: As previous studies showed significant hospital variation in curative treatment of esophagogastric cancer, this study assesses the association between this variation and overall, cancer-specific and recurrence-free survival, and Health-Related Quality of Life (HRQoL). Methods: Patients diagnosed with potentially curable esophageal or gastric cancer between 2015 and 2018 as registered in the Netherlands Cancer Registry were included. Data on overall survival was available for all patients, data on cancer-specific and recurrence-free survival and HRQoL was available for subgroups. Patients were classified according to diagnosis in hospitals with low, medium or high probability of treatment with curative intent (LP, MP or HP). Multivariable models were used to assess the association between LP, MP and HP hospitals and HRQoL and survival. Results: This study includes 7,199 patients with esophageal, and 2,407 with gastric cancer. Overall and cancer-specific survival was better for patients diagnosed in HP versus LP hospitals for both esophageal (HR = 0.82, 95%CI:0.77–0.88 and HR = 0.82, 95%CI:0.75–0.91, respectively), and gastric cancer (HR = 0.82, 95%CI:0.73–0.92 and HR = 0.74, 95%CI:0.64–0.87, respectively). These differences disappeared after adjustments for treatment. Recurrence-free survival was worse for gastric cancer patients diagnosed in HP hospitals (HR = 1.50, 95%CI:1.14–1.96), which disappeared after adjustment for radicality of surgery. Minor, but no clinically relevant, differences in HRQoL were observed.Conclusions: Patients diagnosed in hospitals with a high probability of treatment with curative intent have a better overall and cancer-specific but not recurrence-free survival, while minor differences in HRQoL were observed.</p

Management of emerging multidrug-resistant tuberculosis in a low-prevalence setting

AbstractMultidrug-resistant (MDR) tuberculosis (TB) is an emerging concern in communities with a low TB prevalence and a high standard of public health. Twenty-three consecutive adult MDR TB patients who were treated at our institution between 2007 and 2013 were reviewed for demographic characteristics and anti-TB treatment management, which included surgical procedures and long-term patient follow-up. This report of our experience emphasizes the need for an individualized approach as MDR TB brings mycobacterial disease management to a higher level of expertise, and for a balance to be found between international current guidelines and patient-tailored treatment strategies