Project Retrosight. Understanding the returns from cardiovascular and stroke research: Case Studies

Copyright @ 2011 RAND Europe. All rights reserved. The full text article is available via the link below.This project explores the impacts arising from cardiovascular and stroke research funded 15-20 years ago and attempts to draw out aspects of the research, researcher or environment that are associated with high or low impact. The project is a case study-based review of 29 cardiovascular and stroke research grants, funded in Australia, Canada and UK between 1989 and 1993. The case studies focused on the individual grants but considered the development of the investigators and ideas involved in the research projects from initiation to the present day. Grants were selected through a stratified random selection approach that aimed to include both high- and low-impact grants. The key messages are as follows: 1) The cases reveal that a large and diverse range of impacts arose from the 29 grants studied. 2) There are variations between the impacts derived from basic biomedical and clinical research. 3) There is no correlation between knowledge production and wider impacts 4) The majority of economic impacts identified come from a minority of projects. 5) We identified factors that appear to be associated with high and low impact. This report presents the key observations of the study and an overview of the methods involved. It has been written for funders of biomedical and health research and health services, health researchers, and policy makers in those fields. It will also be of interest to those involved in research and impact evaluation.This study was initiated with internal funding from RAND Europe and HERG, with continuing funding from the UK National Institute for Health Research, the Canadian Institutes of Health Research, the Heart and Stroke Foundation of Canada and the National Heart Foundation of Australia. The UK Stroke Association and the British Heart Foundation provided support in kind through access to their archives

Project Retrosight. Understanding the returns from cardiovascular and stroke research: Methodology Report

Copyright @ 2011 RAND Europe. All rights reserved. The full text article is available via the link below.This project explores the impacts arising from cardiovascular and stroke research funded 15-20 years ago and attempts to draw out aspects of the research, researcher or environment that are associated with high or low impact. The project is a case study-based review of 29 cardiovascular and stroke research grants, funded in Australia, Canada and UK between 1989 and 1993. The case studies focused on the individual grants but considered the development of the investigators and ideas involved in the research projects from initiation to the present day. Grants were selected through a stratified random selection approach that aimed to include both high- and low-impact grants. The key messages are as follows: 1) The cases reveal that a large and diverse range of impacts arose from the 29 grants studied. 2) There are variations between the impacts derived from basic biomedical and clinical research. 3) There is no correlation between knowledge production and wider impacts 4) The majority of economic impacts identified come from a minority of projects. 5) We identified factors that appear to be associated with high and low impact. This report presents the key observations of the study and an overview of the methods involved. It has been written for funders of biomedical and health research and health services, health researchers, and policy makers in those fields. It will also be of interest to those involved in research and impact evaluation.This study was initiated with internal funding from RAND Europe and HERG, with continuing funding from the UK National Institute for Health Research, the Canadian Institutes of Health Research, the Heart and Stroke Foundation of Canada and the National Heart Foundation of Australia. The UK Stroke Association and the British Heart Foundation provided support in kind through access to their archives

The NASA Astrophysics Data System: Architecture

The powerful discovery capabilities available in the ADS bibliographic services are possible thanks to the design of a flexible search and retrieval system based on a relational database model. Bibliographic records are stored as a corpus of structured documents containing fielded data and metadata, while discipline-specific knowledge is segregated in a set of files independent of the bibliographic data itself. The creation and management of links to both internal and external resources associated with each bibliography in the database is made possible by representing them as a set of document properties and their attributes. To improve global access to the ADS data holdings, a number of mirror sites have been created by cloning the database contents and software on a variety of hardware and software platforms. The procedures used to create and manage the database and its mirrors have been written as a set of scripts that can be run in either an interactive or unsupervised fashion. The ADS can be accessed at http://adswww.harvard.eduComment: 25 pages, 8 figures, 3 table

The NASA Astrophysics Data System: The Search Engine and its User Interface

The ADS Abstract and Article Services provide access to the astronomical literature through the World Wide Web (WWW). The forms based user interface provides access to sophisticated searching capabilities that allow our users to find references in the fields of Astronomy, Physics/Geophysics, and astronomical Instrumentation and Engineering. The returned information includes links to other on-line information sources, creating an extensive astronomical digital library. Other interfaces to the ADS databases provide direct access to the ADS data to allow developers of other data systems to integrate our data into their system. The search engine is a custom-built software system that is specifically tailored to search astronomical references. It includes an extensive synonym list that contains discipline specific knowledge about search term equivalences. Search request logs show the usage pattern of the various search system capabilities. Access logs show the world-wide distribution of ADS users. The ADS can be accessed at http://adswww.harvard.eduComment: 23 pages, 18 figures, 11 table

The NASA Astrophysics Data System: Data Holdings

Since its inception in 1993, the ADS Abstract Service has become an indispensable research tool for astronomers and astrophysicists worldwide. In those seven years, much effort has been directed toward improving both the quantity and the quality of references in the database. From the original database of approximately 160,000 astronomy abstracts, our dataset has grown almost tenfold to approximately 1.5 million references covering astronomy, astrophysics, planetary sciences, physics, optics, and engineering. We collect and standardize data from approximately 200 journals and present the resulting information in a uniform, coherent manner. With the cooperation of journal publishers worldwide, we have been able to place scans of full journal articles on-line back to the first volumes of many astronomical journals, and we are able to link to current version of articles, abstracts, and datasets for essentially all of the current astronomy literature. The trend toward electronic publishing in the field, the use of electronic submission of abstracts for journal articles and conference proceedings, and the increasingly prominent use of the World Wide Web to disseminate information have enabled the ADS to build a database unparalleled in other disciplines. The ADS can be accessed at http://adswww.harvard.eduComment: 24 pages, 1 figure, 6 tables, 3 appendice

Case study : a patient-clinician collaboration that identified and prioritized evidence gaps and stimulated research development

Copyright © 2013 Elsevier Inc. All rights reserved.Peer reviewedPostprin

Optical enhancement of sensitivity in laser Doppler velocity systems

Utilization of optical enhancement techniques prevents loss of light by reflections at the photocathode of a photomultiplier and increases signal detection sensitivity