31,859 research outputs found

    Confocal laser scanning microscopy (CLSM) study of hepatocytes cultured on collagen films and gels

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    Summary of paper describing the process whereby primary hepatocyte cultures form an integral part of many hybrid artificial liver designs, and the extracellular matrix environment of the cultures is an important factor for optimal expression of hepatocyte-specific phenotype. This study investigates the effect of incorporating 20% chondroitin-6-sulphate (Ch6SO4), a glycosaminoglycan (GAG), into collagen films and gels, and crosslinking the films and the gels with 1,6-diaminohexane (DAH) on the viability of hepatocytes cultured for 48 hours

    Using ACIS on the Chandra X-ray Observatory as a particle radiation monitor

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    The Advanced CCD Imaging Spectrometer (ACIS) is one of two focal-plane instruments on the Chandra X-ray Observatory. During initial radiation-belt passes, the exposed ACIS suffered significant radiation damage from trapped soft protons scattering off the x-ray telescope's mirrors. The primary effect of this damage was to increase the charge-transfer inefficiency (CTI) of the ACIS 8 front-illuminated CCDs. Subsequently, the Chandra team implemented procedures to remove the ACIS from the telescope's focus during high-radiation events: planned protection during radiation-belt transits; autonomous protection triggered by an on-board radiation monitor; and manual intervention based upon assessment of space-weather conditions. However, as Chandra's multilayer insulation ages, elevated temperatures have reduced the effectiveness of the on-board radiation monitor for autonomous protection. Here we investigate using the ACIS CCDs themselves as a radiation monitor. We explore the 10-year database to evaluate the CCDs' response to particle radiation and to compare this response with other radiation data and environment models.Comment: 10 pages, 5 figures. To appear in Proc. SPIE vol. 773

    AFES Circular 127

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    Lunar sample analysis

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    The surface composition of two samples from the highly shocked, glass-coated lunar basalt (12054) and from four glass-coated fragments from the 1-2 mm (14161) fines were examined by X-ray photoemission spectroscopy to determine whether the agglutination process itself is responsible for the difference between their surface and bulk compositions. Auger electron spectroscopy of glass balls from the 15425 and 74001 fines were analyzed to understand the nature, extent, and behavior of volatile phases associated with lunar volcanism. Initial results indicate that (1) volatiles, in the outer few atomic layers sampled, vary considerably from ball to ball; (2) variability over the surface of individual balls is smaller; (3) the dominant volatiles on the balls are S and Zn; and (4) other volatiles commonly observed are P, Cl, and K

    Determining the Price-Responsiveness of Demands for Irrigation Water Deliveries versus Consumptive Use

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    A water-crop simulation/mathematical programming model of irrigation water demand in northeastern Colorado is formulated to develop an original concept of derived demand for consumptive use of water. Conventional demand functions for water deliveries are also developed, and the effect of hypothetical price increases on both consumption and delivery are illustrated. Findings indicate that demand elasticity estimates are quite sensitive to model specification, and consumptive use demand tends to be significantly less price-responsive than delivery demand. Thus price incentives are likely to have only limited impacts on basin-wide water consumption and would not make much additional water available for emerging demands.crop simulation, irrigation, mathematical programming, water conservation, water-demand elasticities, water policy, Demand and Price Analysis, Resource /Energy Economics and Policy,
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