25,352 research outputs found
The educational turn in art: rewriting the hidden curriculum
Around 2006, the art world developed a prolonged fascination with questions of education, pedagogy and the art school. ‘The Educational Turn’ (Rogoff, 2008) as it became known, produced a plethora of artistic and curatorial practices that engage with educational paradigms and problematics. Prompted in part by the European Union Bologna Process, the Educational Turn provided a critique of education as one-directional knowledge transfer, and the framing of education as a commercialised industry, reduced to the utilitarianism of training for working life. At the same time, it established ‘education’ as a thematic for the art world, in most cases divorced from its capacity for producing change in the fields of art or education. This article asks, what is the hidden curriculum (Illich) of this Educational Turn? Drawing from the writings of Colin Crouch, Wolfgang Streeck and Paulo Virno among others, it suggests that such ‘turns’ without a vital link to the realm of action, contribute to the broader problematic of public programming without a public sphere, through which formerly democratic institutions (like art galleries) operate as shells in a capitalist environment that is increasingly incompatible with democracy. We read The Education Turn here as a missed opportunity to re-shape art curricula and institutions, to develop a movement to oppose the Bologna Accord and the brutal changes imposed on art education through austerity politics. Finally, we argue - citing the writings of Paulo Friere, the mutualist movements in Europe of the 18th and 19th centuries, the educational experiments of Celestin Freinet in and Fernand Oury in France in the 1950s and the pedagogies of feminist and post-colonial struggle - for a deeper connection to radical education genealogies and their contemporary counterparts in contemporary public programming today
Noise-Activated Escape from a Sloshing Potential Well
We treat the noise-activated escape from a one-dimensional potential well of
an overdamped particle, to which a periodic force of fixed frequency is
applied. We determine the boundary layer behavior, and the physically relevant
length scales, near the oscillating well top. We show how stochastic behavior
near the well top generalizes the behavior first determined by Kramers, in the
case without forcing. Both the case when the forcing dies away in the weak
noise limit, and the case when it does not, are examined. We also discuss the
relevance of various scaling regimes to recent optical trap experiments.Comment: 9 pages, no figures, REVTeX, expanded versio
Finite Size Effect on Correlation Functions of a Bose Gas in a Trap and Destruction of the Order Parameter by Phase Fluctuations
The influence of the finite sizes on the coherent properties of 3D Bose
systems is considered. As is shown, the correlation functions of a Bose gas in
a trap have essential differences from analogous correlation functions in an
infinite system. Thus, the anomalous correlation function vanishes due to the
divergency of phase fluctuations which destruct the order parameter too. The
normal correlation function decays exponentially in time for sufficiently large
time interval.Comment: 10 pages, RevTex4, some references have been added some changes in
text are mad
Reduction in jejunal fluid absorption in vivo through distension and cholinergic stimulation not attributable to enterocyte secretion
Jejunal fluid absorption in vivo was reduced by distension and by hydrostatic pressure and further declined on adding E. coli STa enterotoxin but no net fluid secretion was detected. Luminal atropine reduced pressure mediated reductions in fluid absorption to normal values but intravenous hexamethonium was without effect. A neural component to inhibition of absorption by pressure (though not stretch) may be mediated by axon reflexes within cholinergic neurons.Perfusion of cholinergic compounds also reduced net fluid absorption but did not cause secretion. In order to show that these actions were not secretory processes stimulated by cholinergic compounds that offset normal rates of absorption, these compounds were tested for their ability to cause net secretion in loops that were perfused with solutions in which choline substituted for sodium ion. In addition, these perfusates additionally contained E. coli STa enterotoxin or EIPA (ethyl-isopropyl-amiloride) to minimize absorption.In these circumstances, where it might be expected to do so if it were acting through a secretory rather than an absorptive mechanism, carbachol did not cause net fluid secretion. Cholinergic stimulation and pressure induced distension are thought to reduce net fluid absorption through inducing secretion but are found only to reduce fluid absorption.In conclusion, distension and cholinergic stimulation of the small intestine are two further circumstances in which fluid secretion is assumed to explain their action on fluid movement, as required by the enterocyte secretion model of secretion but, which like STa enterotoxin, instead are only able to reduce fluid absorption. This casts further doubt on the widespread validity of the enterocyte secretion model for fluid appearance in the lumen in diarrhoeal diseases
On eternal mean curvature flows of tori in perturbations of the unit sphere
We construct eternal mean curvature flows of tori in perturbations of the
standard unit sphere . This has applications to the study of the
Morse homologies of area functionals over the space of embedded tori in
Genome sequence of canine herpesvirus
Canine herpesvirus is a widespread alphaherpesvirus that causes a fatal haemorrhagic disease of neonatal puppies. We have used high-throughput methods to determine the genome sequences of three viral strains (0194, V777 and V1154) isolated in the United Kingdom between 1985 and 2000. The sequences are very closely related to each other. The canine herpesvirus genome is estimated to be 125 kbp in size and consists of a unique long sequence (97.5 kbp) and a unique short sequence (7.7 kbp) that are each flanked by terminal and internal inverted repeats (38 bp and 10.0 kbp, respectively). The overall nucleotide composition is 31.6% G+C, which is the lowest among the completely sequenced alphaherpesviruses. The genome contains 76 open reading frames predicted to encode functional proteins, all of which have counterparts in other alphaherpesviruses. The availability of the sequences will facilitate future research on the diagnosis and treatment of canine herpesvirus-associated disease
Human papillomavirus E2 regulates SRSF3 (SRp20) to promote capsid protein expression in infected differentiated keratinocytes
The human papillomavirus (HPV) life cycle is tightly linked to differentiation of the infected epithelial cell suggesting a sophisticated interplay between host cell metabolism and virus replication. Previously we demonstrated in differentiated keratinocytes in vitro and in vivo that HPV16 infection caused increased levels of the cellular SR splicing factors (SRSFs) SRSF1 (ASF/SF2), SRSF2 (SC35) and SRSF3 (SRp20). Moreover, the viral E2 transcription and replication factor that is expressed at high levels in differentiating keratinocytes could bind and control activity of the SRSF1 gene promoter. Here we reveal that E2 proteins of HPV16 and HPV31 control expression of SRSFs 1, 2 and 3 in a differentiation-dependent manner. E2 has the greatest trans-activation effect on expression of SRSF3. siRNA depletion experiments in two different models of the HPV16 life cycle (W12E and NIKS16) and one model of the HPV31 life cycle (CIN612-9E) revealed that only SRSF3 contributed significantly to regulation of late events in the virus life cycle. Increased levels of SRSF3 are required for L1 mRNA and capsid protein expression. Capsid protein expression was regulated specifically by SRSF3 and appeared independent of other SRSFs. Taken together these data suggest a significant role of the HPV E2 protein in regulating late events in the HPV life cycle through transcriptional regulation of SRSF3 expression.
IMPORTANCE Human papillomavirus replication is accomplished in concert with differentiation of the infected epithelium. Virus capsid protein expression is confined to the upper epithelial layers so as to avoid immune detection. In this study we demonstrate that the viral E2 transcription factor activates the promoter of the cellular SRSF3 RNA processing factor. SRSF3 is required for expression of the E4Ì‚L1 mRNA and so controls expression of the HPV L1 capsid protein. Thus we reveal a new dimension of virus-host interaction crucial for production of infectious virus. SRSF proteins are known drug targets. Therefore, this study provides an excellent basis for developing strategies to regulate capsid protein production in the infected epithelium and production of new virions
Casimir Effects in Renormalizable Quantum Field Theories
We review the framework we and our collaborators have developed for the study
of one-loop quantum corrections to extended field configurations in
renormalizable quantum field theories. We work in the continuum, transforming
the standard Casimir sum over modes into a sum over bound states and an
integral over scattering states weighted by the density of states. We express
the density of states in terms of phase shifts, allowing us to extract
divergences by identifying Born approximations to the phase shifts with low
order Feynman diagrams. Once isolated in Feynman diagrams, the divergences are
canceled against standard counterterms. Thus regulated, the Casimir sum is
highly convergent and amenable to numerical computation. Our methods have
numerous applications to the theory of solitons, membranes, and quantum field
theories in strong external fields or subject to boundary conditions.Comment: 27 pp., 11 EPS figures, LaTeX using ijmpa1.sty; email correspondence
to R.L. Jaffe ; based on talks presented by the authors at
the 5th workshop `QFTEX', Leipzig, September 200
Character formulas for the operad of two compatible brackets and for the bihamiltonian operad
We compute dimensions of the components for the operad of two compatible
brackets and for the bihamiltonian operad. We also obtain character formulas
for the representations of the symmetric groups and the group in these
spaces.Comment: 24 pages, accepted by Functional Analysis and its Applications, a few
typos correcte
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