Breastfeeding and motor development: A longitudinal cohort study

Background: While there is a large body of work supporting the importance of early feeding practices on cognitive, immunity, behavioural and mental outcomes, few longitudinal studies have focused on motor development. The relationship between duration of breast feeding and motor development outcomes at 10, 14, and 17 years were examined. Methods: Data were obtained from the Western Australian Pregnancy (Raine) Study. There were 2868 live births recorded and children were examined for motor proficiency at 10 (M = 10.54, SD = 2.27), 14 (M = 14.02, SD = 2.33) and 17 (M = 16.99, SD = 2.97) years using the McCarron Assessment of Neuromuscular Development (MAND). Using linear mixed models, adjusted for covariates known to affect motor development, the influence of predominant breast feeding for⩾6 months on motor development outcomes was examined. Results: Breast feeding for ⩾6 months was positively associated with improved motor development outcomes at 10, 14 and 17 years of age (p = 0.019, β 1.38) when adjusted for child’s sex, maternal age, alcohol intake, family income, hypertensive status, gestational stress and mode of delivery. Conclusion: Early life feeding practices have an influence on motor development outcomes into late childhood and adolescence independent of sociodemographic factors. Abbreviations: MAND, McCarron Assessment of Neuromuscular Development; NDI, Neuromuscular Development Index; BP, Blood Pressure; APGAR, appearance pulse, grimace, activity, respiration; SRM, spontaneous rupture of membranes; LC-PUFA, long chain polyunsaturated fatty acids; AA, arachidonic acid; DA, docosahexaenoic aci

Testing limits to airflow perturbation device (APD) measurements

<p>Abstract</p> <p>Background</p> <p>The Airflow Perturbation Device (APD) is a lightweight, portable device that can be used to measure total respiratory resistance as well as inhalation and exhalation resistances. There is a need to determine limits to the accuracy of APD measurements for different conditions likely to occur: leaks around the mouthpiece, use of an oronasal mask, and the addition of resistance in the respiratory system. Also, there is a need for resistance measurements in patients who are ventilated.</p> <p>Method</p> <p>Ten subjects between the ages of 18 and 35 were tested for each station in the experiment. The first station involved testing the effects of leaks of known sizes on APD measurements. The second station tested the use of an oronasal mask used in conjunction with the APD during nose and mouth breathing. The third station tested the effects of two different resistances added in series with the APD mouthpiece. The fourth station tested the usage of a flexible ventilator tube in conjunction with the APD.</p> <p>Results</p> <p>All leaks reduced APD resistance measurement values. Leaks represented by two 3.2 mm diameter tubes reduced measured resistance by about 10% (4.2 cmH₂O·sec/L for control and 3.9 cm H₂O·sec/L for the leak). This was not statistically significant. Larger leaks given by 4.8 and 6.4 mm tubes reduced measurements significantly (3.4 and 3.0 cm cmH₂O·sec/L, respectively). Mouth resistance measured with a cardboard mouthpiece gave an APD measurement of 4.2 cm H₂O·sec/L and mouth resistance measured with an oronasal mask was 4.5 cm H₂O·sec/L; the two were not significantly different. Nose resistance measured with the oronasal mask was 7.6 cm H₂O·sec/L. Adding airflow resistances of 1.12 and 2.10 cm H₂O·sec/L to the breathing circuit between the mouth and APD yielded respiratory resistance values higher than the control by 0.7 and 2.0 cm H₂O·sec/L. Although breathing through a 52 cm length of flexible ventilator tubing reduced the APD measurement from 4.0 cm H₂O·sec/L for the control to 3.6 cm H₂O·sec/L for the tube, the difference was not statistically significant.</p> <p>Conclusion</p> <p>The APD can be adapted for use in ventilated, unconscious, and uncooperative patients with use of a ventilator tube and an oronasal mask without significantly affecting measurements. Adding a resistance in series with the APD mouthpiece has an additive effect on resistance measurements, and can be used for qualitative calibration. A leak size of at least the equivalent of two 3.2 mm diameter tubes can be tolerated without significantly affecting APD measurements.</p

Late Miocene to early Pliocene biofacies of Wanganui and Taranaki Basins, New Zealand: Applications to paleoenvironmental and sequence stratigraphic analysis

The Matemateaonga Formation is late Miocene to early Pliocene (upper Tongaporutuan to lower Opoitian New Zealand Stages) in age. The formation comprises chiefly shellbeds, siliciclastic sandstone, and siltstone units and to a lesser extent non-marine and shallow marine conglomerate and rare paralic facies. The Matemateaonga Formation accumulated chiefly in shelf paleoenvironments during basement onlap and progradation of a late Miocene to early Pliocene continental margin wedge in the Wanganui and Taranaki Basins. The formation is strongly cyclothemic, being characterised by recurrent vertically stacked facies successions, bounded by sequence boundaries. These facies accumulated in a range of shoreface to mid-outer shelf paleoenvironments during conditions of successively oscillating sea level. This sequential repetition of facies and the biofacies they enclose are the result of sixth-order glacio-eustatic cyclicity. Macrofaunal associations have been identified from statistical analysis of macrofossil occurrences collected from multiple sequences. Each association is restricted to particular lithofacies and stratal positions and shows a consistent order and/or position within the sequences. This pattern of temporal paleoecologic change appears to be the result of lateral, facies-related shifting of broad biofacies belts, or habitat-tracking, in response to fluctuations of relative sea level, sediment flux, and other associated paleoenvironmental variables. The associations also show strong similarity in terms of their generic composition to biofacies identified in younger sedimentary strata and the modern marine benthic environment in New Zealand

Nanosphere Synthesis Based on Ferrofluid and Poly Lactic Acid Using Sonication Method

Synthesis study ofmagnetic nanospheres involving wetting, emulsification using sonication and evaporation process have been done. Sonications time were varied for 3 minutes, 4 minutes, 5 minutes, 6 minutes and 7 minutes. Phase analysis result by X-Ray Diffractometer (XRD) showed that Poly Lactic Acid (PLA) tend to change to amorphous phase which become more significant with sonication time. There was no ferrofluid phase change. Size distribution analysis using Scanning Electron Microscope (SEM) showed for longer sonication time, size of nanospherewere decreasing and becomemore homogeneous. Hysteresis curve from measurement using Vibration Sample Magnetometer (VSM) showed increasing of magnetization value with decreasing of nanosphere size, which analized due to higher loading factor of ferrofluid within nanosphere. From these three characterization results, it can be concluded that sample with sonication time of 4 minutes give an optimum nanosphere with respect to its size, homogeneity and the magnetic properties

Pengendalian Suhu Ultrasonikasi pada Pelapisan Nanopartikel Magnet (Fe3O4) dengan Kitosan

Telah dilakukan pelapisan nanopartikel magnetik Fe3O4 dengan proses ultrasonikasi terkendali. Pengendalian ultrasonikasi dilakukan dengan menambahkan fasilitas pendingin baik menggunakan air maupun es serta dengan pengaturan suhu pembatas pada fasilitas ultrasonikasi untuk memastikan suhu sampel maksimal 50 oC selama proses pelapisan kitosan. Nanopartikel hasil pelapisan dianalisis sifat magnetik dan distribusi ukuran partikelnya masing-masing menggunakan VSM (Vibrating Sample Magnetometer) serta PSA (Particle Size Analyzer). Hasil sintesis menunjukkan bahwa penambahan sistem pendingin cukup efektif dalam mengendalikan suhu dan menurunkan waktu total proses pelapisan serta ukuran nanopartikel terlapis kitosan. Namun pola Perubahan ukuran yang terjadi tidak mengikuti sepenuhnya kaidah standar karena adanya proses re-aglomerasi nanopartikel magnetik akibat interaksi magnetik antar nanopartikel yang cukup kuat. Diperoleh hasil pelapisan optimum dengan ukuran nanopartikel magnetik terlapis kitosan sebesar ~ 36,5 nm dan nilai magnetisasi 45 emu/gram pada proses dengan sistem pendingin air. Kondisi ini dicapai dengan waktu total proses pelapisan 60 menit untuk waktu efektif proses ultrasonikasi 10 menit

Pastoralism: Animal health and food safety situation analysis, Kenya and Tanzania

Pastoralism is a farming system in societies that derive majority of their food and income from livestock production. This form of farming system is practised in the world’s arid and semi arid lands (ASALs). It is estimated that 70% of the landmass in the Horn of Africa is dry land; in Kenya 80% of the landmass is classified as ASAL while approximately half of Tanzania consists of dry land. These dry lands can only be effectively utilised when used for livestock rearing, supporting wildlife resource harvesting and tourism. In this paper we present a current situation analysis of animal health and its implication on food safety based on primary data collected from pastoralists in Kajiado County, Kenya and in Tanga and Morogoro regions in Tanzania. Less than 10% of pastoralists in these communities engage in crop farming to supplement household income, and with their high dependency on livestock rearing, animal health challenges are a significant problem. We report on the livestock diseases with high prevalence and postulate their effects on food safety and food security in pastoral communities. We also explore the extent of species rearing diversification, pastoralist trade orientation, and practices that may expose the community and their trading partners to animal and zoonotic infections. We also assess access to animal health service providers within these pastoral areas and veterinary drug usage that may have significant implications on animal health and food safety

Synthesize Modification and Magnetic Characteristic Improvement of Fe/fe Oxide Core/shell Nanopartcle Produce by Borohydryde Reduction Reaction

Nanoparticle of Fe/Fe oxide core/shell structure with high magnetization values has been successfully sinthesized through reduction of FeCl3 by NaBH4 reductor, repeat washing in ethanol, heat treatment at 75 °C and vacuum atmosphere, followed by controlled oxidation with Trimethylamine N-Oxide (TMNO). Morphological structure of the core/shell nanoparticles were evaluated from the image observed with Transmission Electron Microscope (TEM), magnetic properties through the hysteresis curve measured by Vibrating Sample Magnetometer (VSM) while the phase were analysed fromits X-Ray diffraction patterns. Magnetic characteristics of the nanoparticles are found to be affected by the condition of washing process to remove residual phase reactants and heat treatment conditions for the completion of core formation. Too long heating tend to lowered the magnetic properties due to increasing of FeB and Fe2B minor phases. During oxidation process, beside formation of Fe oxide shell on the surface of Fe core, reduction of these minor phases was also proceed and resulted in enhanced ofmagnetic properties. Optimal characteristics of nanoparticle with a crystalline size of ~ 8 nm within Fe core of < 30 nm particle size and Fe oxide shell of ~ 3 nm thickness with saturation magnetization Ms ~ 130 emu/g obtained in the synthesis with 15x washing steps followed by heat treatment at 4 hours

Endoscopic ultrasound is highly accurate and directs management in patients with neuroendocrine tumors of the pancreas

Preoperative localization of pancreatic neuroendocrine tumors with traditional imaging fails in 40–60% of patients. Endoscopic ultrasound (EUS) is highly sensitive in the detection of these tumors. Previous reports included relatively few patients or required the collaboration of multiple centers. We report the results of EUS evaluation of 82 patients with pancreatic neuroendocrine tumors. METHODS : We prospectively used EUS early in the diagnostic evaluation of patients with biochemical or clinical evidence of neuroendocrine tumors. Patients had surgical confirmation of tumor localization or clinical follow-up of >1 yr. RESULTS : Eighty-two patients underwent 91 examinations (cases). Thirty patients had multiple endocrine neoplasia syndrome type I. One hundred pancreatic tumors were visualized by EUS in 54 different patients. The remaining 28 patients had no pancreatic tumor or an extrapancreatic tumor. Surgical/pathological confirmation was obtained in 75 patients. The mean tumor diameter was 1.51 cm and 71% of the tumors were ≤2.0 cm in diameter. Of the 54 explorations with surgical confirmation of a pancreatic tumor, EUS correctly localized the tumor in 50 patients (93%). Twenty-nine insulinomas, 18 gastrinomas, as well as one glucagonoma, one carcinoid tumor, and one somatostatinoma were localized. The most common site for tumor localization was the pancreatic head (46 patients). Most tumors were hypoechoic, homogenous, and had distinct margins. EUS of the pancreas was correctly negative in 20 of 21 patients (specificity, 95%). EUS was more accurate than angiography with or without stimulation testing (secretin for gastrinoma, calcium for insulinoma), transcutaneous ultrasound, and CT in those patients undergoing further imaging procedures. EUS was not reliable in localizing extrapancreatic tumors. CONCLUSIONS : In this series, the largest single center experience reported to date, EUS had an overall sensitivity and accuracy of 93% for pancreatic neuroendocrine tumors. Our results support the use of EUS as a primary diagnostic modality in the evaluation and management of patients with neuroendocrine tumors of the pancreas.Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/75174/1/j.1572-0241.2000.02480.x.pd

Social Forestry - Why and for Whom? a Comparison of Policies in Vietnam and Indonesia

Community forestry or social forestry (henceforth referred collectively as SF) programs have become new modes of forest management empowering local managers and hence, allowing integration of diverse local practices and support of local livelihoods. Implementation of these initiatives, however, face multiple challenges. State-prescribed community programs, for example, will remain isolated efforts if changes in the overall economic and social governance frameworks, including the devolution of rights to local users is lacking. Financial sustainability of these measures remains often uncertain and equity issues inherent to groups and communities formed for SF, can be exacerbated. In this article, we pose the question: Whose interests do SF policies serve? The effectiveness of SF would depend on the motivations and aims for a decentralization of forest governance to the community. In order to understand the underlying motivations behind the governments' push for SF, we examine national policies in Vietnam and Indonesia, changes in their policies over time and the shift in discourses influencing how SF has evolved. Vietnam and Indonesia are at different sides of the spectrum in democratic ambitions and forest abundance, and present an intriguing comparison in the recent regional push towards SF in Southeast Asia. We discuss the different interpretations of SF in these two countries and how SF programs are implemented. Our results show that governments, influenced by global discourse, are attempting to regulate SF through formal definitions and regulations. Communities on the other hand, might resist by adopting, adapting or rejecting formal schemes. In this tension, SF, in general adopted to serve the interest of local people, in practice SF has not fulfilled its promise