88 research outputs found
How Do Institutional Investors Interact With Sell-Side Analysts?
This paper examines how institutional investors interact with sell-side analysts (hereafter, SSAs) in Korean stock market. In particular, we examine the role of institutional investors as a more sophisticated mechanism which incorporates sell-side analysts’ stock recommendation, target price, and earnings forecast more rapidly than individual investors do. Moreover, we examine whether institutional investors differentiate the quality of sell-side analysts’ information. By using a sample of 1,421 firm-year observations in Korean stock market during 2001–2011, we find that the change of institutional investor’s ownership has a significantly positive association with the level of equity value estimates based on SSAs’ earnings forecasts relative to stock prices and their stock recommendation which are considered as SSAs’ indicator of stock market’s mispricing. In addition, we find that only when SSAs provide more accurate earnings forecasts, institutional investors incorporate SSA’s information into their stock trading. Thus, we conclude that institutional investors in Korean stock market contribute to the enhancement of stock market efficiency by incorporating SSAs’ information into their stock trading more rapidly than individual investors. Our findings add to the literature by shedding a light on the unobserved interaction among more sophisticated stock market participants, such as institutional investors and sell-side analysts
Moving In Out and Around the Home: Solutions from Older Adults with Long-term Mobility Impairment
Presented at the 2015 annual conference of Rehabilitative Engineering and Assistive Technology Society of North America (RESNA) in Denver, CO.The purpose of this study was to explore how older adults aging with long-term mobility impairment have adapted to mobility challenges in the home. Through in-home interviews, participants discussed their experience moving in, out and around their home with regard to challenges, solutions, barriers, and changes with age. This paper provides a characterization of the solutions used by participants to overcome in-home mobility challenges as well as unresolved barriers they faced. These themes illustrate the ingenuity of the participants as well as opportunities to support aging in place via design to better match a person’s environment to his/her capabilities
The Student Movement Volume 108 Issue 2: World Changers Assemble!
HUMANS
Meet Pastor Taurus Montgomery, Colin Cha
Uniting AULA with Sofia Oudri, Grace No
World Changers Take On Changing the World, Savannah Tyler
ARTS & ENTERTAINMENT
Bewitched: An Album for the Fall Season, Lexie Dunham
Music Notes for Change Day, Aiko J. Ayala Rios
Processing Through Poetry: Raw & Real, Madison Vath
NEWS
Being Unstoppable: AU Fall Week of Prayer, Jonathan Clough
FIBA Games Spark Questions for Competing Nations Ahead of the \u2724 Summer Olympics, Andrew Francis
Honors\u27 Agape Feast Starts New Year of Faith and Fellowship, Andrew Francis
IDEAS
A Life Worth Living, Reagan Westerman
The Victoria\u27s Secret Fashion Show Returns: Is it a Marketing Tactic or Genuine Change?, Daena Holbrook
PULSE
AU Sports, Alyssa Caruthers
More Change Day Experiences, Various Students
The Strange Thing About Service, Wambui Karanja
Uplifting Spaces on Campus: Reflections from Nicole Compton-Gray, Nicole Compton-Gray
LAST WORD
An Advertising-Free Zone, Scott Moncrieffhttps://digitalcommons.andrews.edu/sm-108/1001/thumbnail.jp
The Student Movement Volume 108 Issue 8: Conducting Us Into The Season
HUMANS
Eating Healthier at Andrews, Brooklyn Anderson
Honors Research with Shania Watts, Grace No
Social Media: Is It Really Social?, Colin Cha
ARTS & ENTERTAINMENT
Journey to the Marvelous God - A double conducting recital, Aiko J. Ayala Rios
Love, Murder, and Secrets: A Night At The MSU French Film Festival, Amelia Stefanescu
What To Do About National Clean Out Your Refrigerator Day, Nate Miller
Places to Go: The Lake Michigan College Mendel Center, Madison Vath
NEWS
Argentina Election Article, Regan McCain
Qualitative Research Writing Group: Your Research Accountability Partner, Melissa Moore
Self-Driving Taxis, Katie Davis
Students\u27 reactions to Andrews\u27s National Ranking, Kiheon Chung
Upcoming Winter Events, Melissa Moore
IDEAS
Morally Gray, Katie Davis
Red and Green Flags, Ruben ColĂłn
Remembering Matthew Perry, Corinna Bevier
SDAs and The Big Bang: A Survey, Erin Beers
Shoot Your Shot - Or Maybe Not?, Regan Westerman
PULSE
Burnout vs. Laziness: What\u27s The Difference?, Lexie Dunham
How Habits Happen, Anna Rybachek
The Mauricio Fund, Elianna Fisher
LAST WORD
Reality for a Second-Generation Immigrant, Gio Leehttps://digitalcommons.andrews.edu/sm-108/1007/thumbnail.jp
Translation, Cultural Adaptation, and Validation of a Korean Version of the Information Needs in Cardiac Rehabilitation Scale
Objective To translate and culturally adapt the Information Needs in Cardiac Rehabilitation (INCR) questionnaire into Korean and perform psychometric validation. Methods The original English version of the INCR, in which patients are asked to rate the importance of 55 topics, was translated into Korean (INCR-K) and culturally adapted. The INCR-K was tested on 101 cardiac rehabilitation (CR) participants at Kangwon National University Hospital and Seoul National University Bundang Hospital in Korea. Structural validity was assessed using principal component analysis, and Cronbach’s alpha of the areas was computed. Criterion validity was assessed by comparing information needs according to CR duration and knowledge sufficiency according to receipt of education. Half of the participants were randomly selected for 1 month of re-testing to assess their responsiveness. Results Following cognitive debriefing, the number of items was reduced to 41 and ratings were added to assess participants’ sufficient knowledge of each item. The INCR-K structure comprised eight areas, each with sufficient internal consistency (Cronbach’s alpha>0.7). Criterion validity was supported by significant differences in mean INCR-K scores based on CR duration and knowledge sufficiency ratings according to receipt of education (p<0.05). Information needs and knowledge sufficiency ratings increased after 1 month of CR, thus supporting responsiveness (p<0.05). Conclusion The INCR-K demonstrated adequate face, content, cross-cultural, structural, and criterion validities, internal consistency, and responsiveness. Information needs changed with CR, such that multiple assessments of information needs may be warranted as rehabilitation progresses to facilitate patient-centered education
β-N-Methylamino-L-alanine Induces Neurological Deficits and Shortened Life Span in Drosophila
The neurotoxic non-protein amino acid, β-N-methylamino-L-alanine (BMAA), was first associated with the high incidence of Amyotrophic Lateral Sclerosis/Parkinsonism Dementia Complex (ALS/PDC) in Guam. Recently, BMAA has been implicated as a fierce environmental factor that contributes to the etiology of Alzheimer’s and Parkinson’s diseases, in addition to ALS. However, the toxicity of BMAA in vivo has not been clearly demonstrated. Here we report our investigation of the neurotoxicity of BMAA in Drosophila. We found that dietary intake of BMAA reduced life span, locomotor functions, and learning and memory abilities in flies. The severity of the alterations in phenotype is correlated with the concentration of BMAA detected in flies. Interestingly, developmental exposure to BMAA had limited impact on survival rate, but reduced fertility in females, and caused delayed neurological impairment in aged adults. Our studies indicate that BMAA exposure causes chronic neurotoxicity, and that Drosophila serves as a useful model in dissecting the pathogenesis of ALS/PDC
Toward the development of transcriptional biodosimetry for the identification of irradiated individuals and assessment of absorbed radiation dose
Components of the LINC and NPC complexes coordinately target and translocate a virus into the nucleus to promote infection.
Nuclear entry represents the final and decisive infection step for most DNA viruses, although how this is accomplished by some viruses is unclear. Polyomavirus SV40 transports from the cell surface through the endosome, the endoplasmic reticulum, and the cytosol from where it enters the nucleus to cause infection. Here we elucidate the nuclear entry mechanism of SV40. Our results show that cytosol-localized SV40 is targeted to the nuclear envelope by directly engaging Nesprin-2 of the linker of nucleoskeleton and cytoskeleton (LINC) nuclear membrane complex. Additionally, we identify the NUP188 subunit of the nuclear pore complex (NPC) as a new Nesprin-2-interacting partner. This physical proximity positions the NPC to capture SV40 upon release from Nesprin-2, enabling the channel to facilitate nuclear translocation of the virus. Strikingly, SV40 disassembles during nuclear entry, generating a viral genome-VP1-VP3 subcomplex that efficiently crosses the NPC to enter the nucleus. Our results reveal how two major nuclear membrane protein complexes are exploited to promote targeting and translocation of a virus into the nucleus
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